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Clinical trials and research at Centre Hospitalier Universitaire de Saint Etienne
As of November 12, 2026, Find a Trial lists 91 clinical trials run by Centre Hospitalier Universitaire de Saint Etienne that are recruiting, at sites in 2 countries (most in France (91), Switzerland (2)). By phase: Phase 4 (4), Phase 3 (2), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 91Clinical trials
- 2Countries
Newest trials
All recruiting trials (91)
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Single Port Robotic System for Pediatric Surgery
This study tests whether the Single Port robotic system can be safely used to perform certain pediatric abdominal surgeries (like pyeloplasty and reflux procedures) in children aged 1 to 17.
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Sensory neuronopathy: finding the best disease scales for tracking progression
This study tests which clinical scales best measure disease severity and progression in adults with sensory neuronopathy.
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Multimodal approach to reduce urinary incontinence in young female athletes
A multimodal program combining pelvic health education and core stability training is tested to see if it reduces urinary incontinence in young nulliparous female athletes.
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Remediation of memory impairments using motor encoding and dynamic imagery in Alzheimer’s disease
This trial tests whether combining real action, motor imagery, and dynamic video cues can help memory in people with early Alzheimer’s disease and compares it to a control group without Alzheimer’s.
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Autologous Serum Eye Drops for Severe Dry Eye: Protein Factors and Response
This study tests whether the protein makeup of a patient’s own serum eye drops explains how well those drops work for severe dry eye.
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Video therapy to help leg movement after stroke
A pilot study tests whether intensive video therapy added to usual rehabilitation can boost lower-limb recovery in people a month to a year after stroke.
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Endurance Challenge: Can sedentary adults complete extreme endurance training
A group of previously inactive adults will try an 18-month intensive endurance program to see if a very ambitious training goal can help them start and stick with gradual, strenuous exercise.
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Measuring skin damage in systemic sclerosis with ADHELASKIN
ADHELASKIN will be tried to measure skin thickness and firmness in people with systemic sclerosis.
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Polishing the Descemet membrane before endothelial keratoplasty for Fuchs endothelial corneal dystrophy
This trial tests whether polishing the diseased Descemet membrane before injecting cultured endothelial cells helps improve graft adhesion and outcomes for people with Fuchs endothelial corneal dystrophy.
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Do fewer long workouts improve resilience to endurance exercise compared with more frequent short workouts?
We will test whether doing fewer long workouts instead of more frequent short workouts helps recreational endurance athletes resist performance decline during prolonged exercise.
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Muscle along the spine on a CT scan to predict 3-month survival after septic shock
This study tests whether measurements from a CT scan of the lower back muscles taken around ICU admission can help predict mortality 3 months after discharge for patients with septic shock.
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Evening Music-Based Intervention for Sleep and Behavior in Alzheimer's Patients
Researchers will test a therapist-led evening music program to help people with Alzheimer’s or related disorders in secure care units see if it reduces sundowning and improves behavior, compared to listening to an audiobook.
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Heart-rate and sweat testing for autonomic problems in children with type 1 diabetes
This study will test whether 24-hour heart-rate monitoring and a skin conductance device can detect autonomic nerve dysfunction in children with type 1 diabetes compared with same-age healthy children.
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Mind-body therapies to help anxiety in young cancer survivors
This study tests whether hypnosis and relaxation, added to usual care, can reduce anxiety in children, teens, and young adults who have survived cancer.
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Does shorter local vibration improve knee muscle function?
This trial tests whether short local vibration sessions on the knee can improve neuromuscular function in healthy adults aged 18–45.
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Morning versus late-afternoon aerobic exercise: effects on sleep in endurance athletes and inactive people
This trial will test if doing aerobic exercise in the morning versus the late afternoon changes deep sleep, how quickly you fall asleep, and core body temperature in endurance athletes and inactive adults.
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Insole Optimization for Rheumatoid Arthritis Patients
We’re testing a digital model to design better orthopedic insoles to help people with rheumatoid arthritis who have foot pain and forefoot involvement.
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Evening caregiver-led music sessions to help sleep and behavior in people with Alzheimer’s in protected living
This project will test whether ritualized, familiar music sessions led by caregivers after meals help people with Alzheimer's in a protected living unit fall asleep faster and have fewer behavioral problems.
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rTMS over the motor cortex for cancer-related neuropathic pain
This trial will try high-frequency rTMS over the primary motor cortex to relieve chronic neuropathic pain in adults with cancer who have not responded to standard drug treatments.
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How blood vessel walls age
This project will test how arteries and veins age by collecting graft tissue from adults having coronary artery bypass grafting (CABG).
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Imaging and follow-up of pigmented tumors on the front of the eye in children
This project will use painless imaging to see if watching pigmented tumors on the front of the eye can guide follow-up and reduce unnecessary surgery for children under 18.
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Rapid screening for anxiety and depression in children, teens, and young adults treated for cancer
This study tests a short questionnaire to quickly find anxiety or depression in children, adolescents, and young adults who were treated for cancer.
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Personalized 6-month program to reduce frailty around bladder or kidney cancer surgery
This program will try personalized exercise, education workshops, and referral to a rehabilitation service before and after surgery to reduce frailty in older people having bladder or kidney cancer operations.
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Outdoor versus indoor exercise to reduce negative symptoms in schizoaffective disorder
This project will test whether 8 weeks of outdoor exercise helps adults (18–55) with schizoaffective disorder and persistent negative symptoms more than the same exercise done indoors.
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Focal muscle vibration to limit leg muscle weakness during reduced use
This trial will see if a 10-day program of focal muscle vibration can limit strength loss in healthy adults whose one leg is temporarily unloaded.
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Understanding vaccination attitudes during mild fever
This study looks at how healthcare workers and the general public feel about getting vaccinated when they have a mild fever to see what might help or stop them from getting vaccinated in those situations.
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Skin effects of D-penicillamine in people with Wilson disease
This project will use silicone molds and confocal imaging to see if D-penicillamine changes skin elasticity in people with Wilson disease compared with matched healthy volunteers.
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Combining visual and proprioceptive feedback during motor imagery after hemiparetic stroke
This test will see if using a computerized mirror and tendon vibration during motor imagery changes brain activity in adults with hemiparetic stroke.
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Sleep extension to reduce performance loss from sleep deprivation
This trial tests whether adding extra sleep in the days before long runs helps healthy adult runners resist the fatigue and performance decline caused by partial or total sleep deprivation.
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Exploring the connection between brain tumor patients and their pets
This study looks at how having a brain tumor affects patients' ability to care for their pets and how it impacts both the patients and their pets emotionally.
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Adapted exercise plus targeted nutrition to help women with constitutional thinness gain muscle
This trial will test whether a tailored physical activity program combined with compensatory nutrition helps adult women with constitutional thinness gain lean (muscle) mass.
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Three approaches to reduce fatigue in Sjögren's syndrome
This trial will try adapted physical activity alone, adapted physical activity plus acupuncture, and adapted physical activity plus transcutaneous vagal nerve stimulation to see if they reduce chronic fatigue in adults with Sjögren's syndrome.
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Purine-rich diet for patients with AICA-ribosiduria
This study is testing whether a purine-rich diet can help people with AICA-ribosiduria feel better by reducing their symptoms.
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Combining motor imagery and tendon vibration to boost motor pathway activation
This project will test whether adding tendon vibration to imagined movements helps increase motor system activation in healthy adults.
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PCV-20 vaccination for adults during a short febrile illness
This test sees if giving the PCV-20 pneumococcal vaccine to adults hospitalized with a short, non-severe fever produces the same immune response and safety as giving it after the fever has resolved.
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Characterizing extracellular vesicles and blood–brain barrier changes during CAR‑T therapy to understand ICANS
This research will try to see if tracking extracellular vesicles in blood and MRI markers of blood–brain barrier change can help detect or explain ICANS in adults receiving CAR‑T cell therapy.
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Investigating Staphylococcus aureus in the nose of patients with bacteremia
This study is trying to see if Staphylococcus aureus bacteria found in the nose of patients with blood infections can affect their treatment and recovery.
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DBT group program for adults with emotional dysregulation across different diagnoses
This program tries a shortened (4–5 month) DBT group course to see if it improves emotion regulation in adults (18–65) with conditions like borderline personality disorder, bipolar disorder, PTSD, addictions, or eating disorders.
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Testing fatigue levels in patients with spinal muscular atrophy
This study is testing new ways to measure fatigue in people with spinal muscular atrophy to help them manage their daily activities better.
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Comparing high-resolution and pQCT scans to view bone and muscle structure
This study will try high-resolution CT (HR-pQCT), pQCT, and DXA scans to see if they reveal bone and muscle microarchitecture changes in adults at risk of osteoporosis or muscle loss.
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Individualized tapering strategy for rheumatoid arthritis treatment
This study is testing a personalized plan for reducing medication in people with rheumatoid arthritis who are in remission to see if it helps prevent flare-ups.
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Apixaban's effect on blood clotting in newly diagnosed multiple myeloma
This test sees if apixaban lowers blood clotting more in people with newly diagnosed multiple myeloma than in people taking apixaban after knee replacement.
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Evaluating residual embolism using advanced imaging techniques
This study is testing new imaging techniques to see if they can better measure leftover blood clots in the lungs of patients with chronic blood vessel blockages.
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Strengthening muscles to help with moderate obstructive sleep apnea
This study is testing whether a special exercise program that strengthens breathing muscles can help people with moderate sleep apnea sleep better and have fewer breathing issues at night.
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Thrombin generation testing to predict bleeding in cancer patients on anticoagulants for thrombosis
This project will test whether a thrombin generation blood test can help predict which cancer patients treated with anticoagulants for a recent deep vein thrombosis or pulmonary embolism are more likely to have bleeding within six months.
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Evaluating ACL revision surgery practices in France
This study looks at how ACL revision surgeries are done in France to see what works best and how patients are doing afterward.
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Evaluating patient information in interventional radiology
This study is testing different ways to provide information to patients about interventional radiology procedures, like cementoplasty, to see how well they understand their treatment options.
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Hydroxychloroquine for IgA Nephropathy: See If It Helps Manage the Disease
This study tests whether hydroxychloroquine can help people with IgA nephropathy, to see if it reduces kidney damage and protein in the urine.
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Evaluating infant crying as a predictor of neurodevelopment
This study is trying to see if the sounds of crying from newborns can help predict how well they will develop by the time they are two years old.
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Using first-void urine for HPV testing in cervical cancer screening
This study is testing whether using urine samples instead of traditional methods for HPV testing can help more women in France get screened for cervical cancer.
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Comparing Vedolizumab and Adalimumab for Crohn's Disease Treatment
This study is testing whether switching to Vedolizumab or increasing the dose of Adalimumab works better for people with Crohn's disease who aren't responding to their current Adalimumab treatment.
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Managing alarm noise in intensive care units to improve patient safety
This study is testing a new way to manage alarm sounds in intensive care units to see if it can make the environment safer and less stressful for patients and staff.
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Using vagus nerve stimulation with exercise to help chronic fatigue
This study is testing if using a special nerve stimulation along with a tailored exercise program can help people with chronic fatigue from fibromyalgia or long Covid feel better and recover faster.
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Evaluating the elasticity of the mitral valve in living humans
This study is trying to see how stretchy the mitral valve chords are in people who need mitral valve replacement, comparing those with mitral valve prolapse to those with a different heart condition.
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Neuromodulation for treating neuropathic pain and depression
This study is testing if a special brain treatment can help people with both nerve pain and depression feel better when regular pain medications haven't worked.
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Having your pet visit you while you're in intensive care
This trial will test whether visits from a patient's own dog or cat help reduce anxiety, improve mood, and lower stress in conscious adults recovering in the ICU.
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Analysis of end-of-life care practices in elderly patients
This study looks at how doctors care for elderly patients in their last week of life to see when they switch from active treatments to comfort care.
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Examining the effects of frailty and ICU-acquired weakness on fatigue after ICU discharge
This study is trying to see how being weak from a long stay in the ICU affects tiredness after leaving the hospital for people who have been in the ICU for a while.
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Local vibrations to improve recovery in stroke patients
This study is testing if adding local vibrations to regular rehab can help stroke patients recover their walking speed better than rehab alone.
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Monitoring opioids and sedatives to prevent organ dysfunction and mortality after surgery
This study tests if closely watching pain and sedation levels during surgery can help older patients avoid serious complications and live longer after high-risk operations.
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Comparing two methods for performing hysterectomy
This study is testing whether a new way of doing hysterectomy through the vagina is safer and easier for women with larger uteri compared to the traditional laparoscopic method.
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Evaluating cement treatment for pelvic bone lesions in elderly patients
This study looks at whether a minimally invasive cement treatment can help older patients with pelvic bone fractures or tumors feel better and recover safely.
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Early identification program for first-episode psychosis
This study tests a program that helps people with early signs of psychosis get the care they need faster to improve their chances of recovery.
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Integrating nursing care to enhance patient partnership in managing chronic diseases
This study is testing a new way for nurses to work with patients who have chronic diseases to create personalized care plans that help them manage their health better.
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Analyzing genetic and clinical factors in Fuchs' Corneal Endothelial Dystrophy
This study is trying to see how genetic and clinical differences in people with Fuchs' Corneal Endothelial Dystrophy can help improve diagnosis and treatment options.
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Physical activity support for prostate cancer patients
This study is trying to see if a personalized support program can help prostate cancer patients become more active by encouraging them to walk more, which may improve their health and reduce cancer risks.
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Combining physical activity and education for patients with chronic Lyme disease symptoms
This study tests whether a program that combines exercise and education can help people with chronic Lyme disease symptoms feel better.
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Comparing antithrombotic therapies for patients with acute venous thromboembolism and a history of cardiovascular disease
This study is testing if combining blood thinners with another type of medication can help people with blood clots and a history of heart disease stay safe and healthy.
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Impact of Mother-of-pearl Supplement on Preventing Osteoporosis in Post-menopausal Women
This study tests whether taking mother-of-pearl supplements can help prevent osteoporosis in post-menopausal women aged 50 to 65 who are at risk for the condition.
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Identifying a proteomic pattern for diagnosing chronic thromboembolic pulmonary hypertension
This study is trying to find a specific pattern in blood proteins to help doctors better diagnose chronic thromboembolic pulmonary hypertension in patients who have symptoms like shortness of breath.
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Optimized rehabilitation program for ACL recovery before returning to sports
This study tests if a personalized rehab program with regular check-ins can help people recover better from ACL surgery and safely get back to sports.
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Understanding how nonverbal sounds affect our body and mind
This study is testing how different nonverbal sounds, like screams and laughter, affect how our minds and bodies respond.
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Understanding nonverbal vocal signals and their effects on the body
This study looks at how different sounds we make, like screams and laughter, affect our bodies to better understand their meaning and purpose.
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Combining screw fixation and cement injection for bone metastases
This study is testing if combining screw fixation with cement injection can help people with painful bone metastases manage their pain better and reduce the chance of fractures.
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Rituximab treatment for patients with anti-MAG neuropathy who are likely to respond
This study is testing if rituximab can help people with anti-MAG neuropathy who have had the disease for less than two years and have high anti-MAG levels.
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Understanding Drug Interactions in Chronic Myeloid Leukemia Treatment
This study is testing how different treatments work together for people with Chronic Myeloid Leukemia who are taking Tyrosine Kinase Inhibitors to see if adjusting their medications can help them do better.
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Examining platelet structure in ischemic stroke patients before and after antiplatelet treatment
This study is testing how antiplatelet treatment affects the structure of blood platelets in patients who have had an ischemic stroke to see if it can help prevent future strokes.
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Using brain stimulation to reduce cannabis use in patients with schizophrenia
This study is testing if brain stimulation can help people with schizophrenia who also use cannabis to reduce their cannabis use and improve their daily functioning.
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Combining rTMS with virtual reality mirror therapy for neuropathic pain relief
This study is testing if combining a brain stimulation technique with virtual reality therapy can help people with nerve pain feel better.
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Using ultrasound to assess the severity of lateral ankle sprains
This study is testing if ultrasound can better show how bad a lateral ankle sprain is compared to just a physical exam for people who have recently injured their ankle.
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Follow-up on ACL reconstruction outcomes
This study looks at how well people recover after having surgery to fix their torn ACL, to see what works best for their healing and recovery.
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Evaluating biomarkers' effects on immune response after stem cell transplants
This study is testing how certain markers in the blood can help us understand the immune response in adults receiving stem cell transplants for blood cancers.
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Understanding factors affecting treatment for pectus carinatum using a compression system
This study looks at how different factors like age and gender affect the success of a chest compression treatment for people with pectus carinatum.
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Examining how nonverbal vocalizations affect pain tolerance
This study tests how making sounds like screaming or laughing while your hand is in cold water can change how much pain you can handle in healthy adults.
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Examining how non-verbal vocalizations affect pain tolerance
This study tests whether listening to sounds like babies crying can change how much pain healthy adults can handle when their hand is in cold water.
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Creating a serum bank to find early markers for pancreatic cancer
This study is trying to collect blood samples from people with pancreatic cancer to see if certain markers can help catch the disease earlier.
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Using atropine eyedrops to treat myopia in children
This study tests whether daily atropine eyedrops can help children with worsening nearsightedness see better.
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Detecting urinary exosomes in patients with clear cell renal cell carcinoma
This study is testing a new way to find cancer markers in urine from patients with clear cell kidney cancer to see if it can help with early diagnosis.
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Testing a blood assay to predict Cytomegalovirus reactivation in Ulcerative Colitis patients
This study is testing a blood test to see if it can help predict when people with Ulcerative Colitis might have a Cytomegalovirus reactivation, so they can avoid unnecessary biopsies.
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Evaluating a Biomarker for Disease Activity in Primary Sjögren's Syndrome
This study is testing if measuring a specific type of antibody in the blood can help doctors understand how active the disease is in people with Primary Sjögren's Syndrome.
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Identifying first-episode psychosis patients who do not respond to first-line treatment
This project will try to see if MRI brain markers and machine-learning methods can predict which people aged 18–35 with a first episode of psychosis will not have symptom remission after three months.
Quick answers
How many clinical trials run by Centre Hospitalier Universitaire de Saint Etienne are recruiting right now?
91, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in France (91 trials), Switzerland (2 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 4: 4, Phase 3: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.