Physical activity support for prostate cancer patients
Official title: Title Impact of a Physical Activity Intervention With Motivational Support From Peers for Prostate Cancer Patients - ACTI-PAIR 2 Multicenter, Randomized Stepped-wedge Study
Run by Centre Hospitalier Universitaire de Saint Etienne · NCT05739565 · Data updated 2026-11-12
This study is trying to see if a personalized support program can help prostate cancer patients become more active by encouraging them to walk more, which may improve their health and reduce cancer risks.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | Men only |
| Enrollment | 850 (estimated) |
| Sponsor | Centre Hospitalier Universitaire de Saint Etienne Academic / other |
| Locations | 25 sites (Chambéry and 24 other locations) |
| Status | Recruiting |
| Started | April 25, 2023 |
| Main results expected | September 30, 2027 |
| Study ends | September 30, 2028 |
| Registry record updated | November 24, 2025 |
| Trial ID | NCT05739565 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are prostate cancer patients aged 18 and older who are currently inactive and have been diagnosed for at least one year.
✕Probably not a fit
Patients undergoing treatment for prostate cancer (except hormone therapy) or those with significant comorbidities that prevent physical activity may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to improve physical activity levels among prostate cancer patients by implementing a personalized intervention program that combines support from health professionals and peers. The program encourages patients to engage in at least 150 minutes of brisk walking per week, which is linked to reduced cancer mortality and recurrence. By utilizing physical activity support devices and personalized coaching, the study seeks to initiate and sustain regular physical activity over the long term. The intervention targets patients who are currently insufficiently active and have been diagnosed with prostate cancer for at least one year.
Why it matters
Potential benefit: If successful, this intervention could significantly enhance the quality of life and survival rates for prostate cancer patients through increased physical activity.
How similar studies have gone: Previous studies have shown that personalized physical activity interventions can be effective, but this approach aims to establish long-term sustainability, making it a novel contribution to the field.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Patients: * Age ≥ 18 years * Diagnosed with prostate cancer for at least 1 year * PA practice \< 150 minutes per week (considered inactive according to WHO) * Affiliated or entitled to a social security scheme * Having received informed information about the study and having co-signed, with the investigator, a consent to participate in the study Exclusion Criteria: For patients: * Undergoing treatment (except hormone therapy) * Significant comorbidities contraindicating the practice of physical activity: associated cardiac pathologies, respiratory pathologies, disabling joint pathologies * Deprived of liberty or under guardianship
Where it's running
-
CHU Saint-Etienne - Oncologie
Saint-Etienne, France Recruiting -
Hôpital Privé de la Loire
Saint-Etienne, France Recruiting -
Activité Physique Adaptée - CDOS Savoie
Chambéry, France Not yet recruiting -
CH Chambéry
Chambéry, France Not yet recruiting -
Activité Physique Adaptée - DAHLIR 63
Clermont-Ferrand, France Not yet recruiting -
CHU Clermont-Ferrand - ONCOLOGIE
Clermont-Ferrand, France Not yet recruiting
Show 19 more locations
-
CHU Clermont-Ferrand - Urologie
Clermont-Ferrand, France Not yet recruiting -
Activité Physique Adaptée - CDOS Isère
Grenoble, France Not yet recruiting -
CHU Grenoble - Urologie
Grenoble, France Not yet recruiting -
Activité Physique Adaptée - DAHLIR 43
Le Puy-en-Velay, France Not yet recruiting -
CH Le Puy en Velay
Le Puy-en-Velay, France Not yet recruiting -
HCL - Hôpital Edouard Herriot
Lyon, France Not yet recruiting -
HCL - Hôpital Croix Rousse
Lyon, France Not yet recruiting -
Activité Physique Adaptée - DAHLIR 69
Lyon, France Not yet recruiting -
CLB - Oncologie
Lyon, France Not yet recruiting -
CLB - Radiothérapie
Lyon, France Not yet recruiting -
HCL - CH Lyon Sud
Lyon, France Not yet recruiting -
Activité Physique Adaptée - CDOS Ardèche
Privas, France Not yet recruiting -
CH Roanne
Roanne, France Not yet recruiting -
Activité Physique Adaptée - DAPAP 42
Saint-Etienne, France Not yet recruiting -
CHU Saint-Etienne - Radiothérapie
Saint-Etienne, France Not yet recruiting -
Clinique du parc
Saint-Priest-en-Jarez, France Not yet recruiting -
Activité Physique Adaptée - CDOS Drôme
Valence, France Not yet recruiting -
Hôpitaux Drôme Nord - Valence
Valence, France Not yet recruiting -
Radiologie Drôme-Ardèche - Valence
Valence, France Not yet recruiting
Study contacts
- Principal investigator: David HUPIN, MD PhD — CHU de Saint-Etienne
- Study coordinator: Hupin David, Md
- Email: David.Hupin@chu-st-etienne.fr
- Phone: (0)477828413
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Targeted alpha therapy for B7-H3 expressing solid tumors using AKY-2519
This phase 1b trial tests a radiolabeled drug (AKY-2519) to see if it's safe and tolerable in adults with B7-H3 positive advanced solid tumors, including NSCLC and SCLC, with imaging to help guide use.
-
PSMA-guided surgery and tissue-resident T cells in node-positive prostate cancer
This study tests whether PSMA-guided surgery can help identify and study tissue-resident T cells in prostate cancer that has spread to lymph nodes.
-
Predictive factors for response to Lu-177 PSMA therapy in metastatic castration-resistant prostate cancer
This study tests whether imaging, dose measurements, and blood tests can predict which men with metastatic castration-resistant prostate cancer will respond to Lu-177 PSMA therapy.
-
Salvage high-dose-rate brachytherapy for locally recurrent prostate cancer
This observational study tests whether salvage HDR brachytherapy can help men with locally recurrent prostate cancer after initial radiotherapy, using advanced imaging and biopsy to guide treatment.
-
Multi-peptide Vaccination and PSMAxCD3 Antibody Therapy for Prostate Cancer with Biochemical Recurrence
This phase 2 trial tests whether a PSMA-targeted bispecific antibody (CC-1), a prostate cancer peptide vaccine (VAC-XS15-PC01), or both can be given safely and help control biochemical recurrence after local therapy in men with prostate cancer.
-
Lutetium-177 Ludotadipep for advanced prostate cancer
This study tests whether adding Lu-177 Ludotadipep to standard care helps men with metastatic castration-resistant prostate cancer live longer without their disease getting worse.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.