Clinical trial Recruiting at 1 site Interventional Ages 30 to 65 Women only

Using first-void urine for HPV testing in cervical cancer screening

Official title: Evaluation of First-void Urine as an Alternative to Cervical Sampling for Human Papillomavirus (HPV) Testing in Cervical Cancer Screening (Single-center Study).

Run by Centre Hospitalier Universitaire de Saint Etienne · NCT06254846 · Data updated 2026-11-12

This study is testing whether using urine samples instead of traditional methods for HPV testing can help more women in France get screened for cervical cancer.

Quick facts

Study typeInterventional
Ages30 Years to 65 Years
SexWomen only
Enrollment350 (estimated)
SponsorCentre Hospitalier Universitaire de Saint Etienne
Academic / other
Locations1 site (Saint-Etienne)
StatusRecruiting
StartedMay 23, 2024
Main results expectedMay 2027
Study endsMay 2027
Registry record updatedMay 6, 2026
Trial IDNCT06254846 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are women aged 30 to 65 who are seeking primary cervical cancer screening.

Probably not a fit

Patients outside the age range of 30 to 65 or those not consulting for cervical cancer screening may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of using first-void urine samples as an alternative to traditional cervical sampling for HPV testing in cervical cancer screening. The research aims to address the low screening rates in France, where invasive cervical sampling is a significant barrier. By implementing a standardized urine collection protocol, the study seeks to determine the sensitivity of HPV PCR tests on urine samples and assess the acceptability of this method through participant questionnaires.

Why it matters

Potential benefit: If successful, this approach could make cervical cancer screening more accessible and comfortable for women.

How similar studies have gone: While some studies have explored urine testing for HPV, this specific approach with standardized collection is novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Female
* Age between 30 and 65
* Consulting in the Gynecology-Obstetrics department for primary cervical cancer screening
* Patient affiliated or entitled to a social security regimen
* Patient who has received information about the study and expressed non-opposition

Exclusion Criteria:

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Where it's running

  • Service de Gynécologie Obstétrique - CHU Saint-Etienne
    Saint-Etienne, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.