Using first-void urine for HPV testing in cervical cancer screening
Evaluation of First-void Urine as an Alternative to Cervical Sampling for Human Papillomavirus (HPV) Testing in Cervical Cancer Screening (Single-center Study).
NA · Centre Hospitalier Universitaire de Saint Etienne · NCT06254846
This study is testing whether using urine samples instead of traditional methods for HPV testing can help more women in France get screened for cervical cancer.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 350 (estimated) |
| Ages | 30 Years to 65 Years |
| Sex | Female |
| Sponsor | Centre Hospitalier Universitaire de Saint Etienne (other) |
| Locations | 1 site (Saint-Etienne) |
| Trial ID | NCT06254846 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of using first-void urine samples as an alternative to traditional cervical sampling for HPV testing in cervical cancer screening. The research aims to address the low screening rates in France, where invasive cervical sampling is a significant barrier. By implementing a standardized urine collection protocol, the study seeks to determine the sensitivity of HPV PCR tests on urine samples and assess the acceptability of this method through participant questionnaires.
Who should consider this trial
Good fit: Ideal candidates for this study are women aged 30 to 65 who are seeking primary cervical cancer screening.
Not a fit: Patients outside the age range of 30 to 65 or those not consulting for cervical cancer screening may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could make cervical cancer screening more accessible and comfortable for women.
How similar studies have performed: While some studies have explored urine testing for HPV, this specific approach with standardized collection is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Female * Age between 30 and 65 * Consulting in the Gynecology-Obstetrics department for primary cervical cancer screening * Patient affiliated or entitled to a social security regimen * Patient who has received information about the study and expressed non-opposition Exclusion Criteria: \-
Where this trial is running
Saint-Etienne
- Service de Gynécologie Obstétrique - CHU Saint-Etienne — Saint-Etienne, France (RECRUITING)
Study contacts
- Principal investigator: Louise MONIOD, MD — Centre Hospitalier Universitaire de Saint Etienne
- Study coordinator: Louise MONIOD, MD
- Email: louise.moniod@chu-st-etienne.fr
- Phone: (0)4 77 82 83 83
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Uterine Cervical Cancer, HPV, Cervical cancer, Cancer screening