Evaluating the elasticity of the mitral valve in living humans

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the mechanobiological and histological characteristics of mitral valve chords in living humans, a topic that has not been previously explored in the literature. The study will involve 20 patients scheduled for mitral valve replacement, who will be grouped based on their specific mitral valve conditions. Data will be collected on patient history and intraoperative results, with a focus on comparing the elasticity of mitral valve chords between patients with mitral valve prolapse and those with restrictive ischemic mitral valve. The harvested tissue will be preserved in natural conditions to ensure accurate analysis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

All patients programmed for mitral valve replacement who have more than 45 years old

Exclusion Criteria:

* Patients with mitral calcification
* Mitral valve rheumatic disease
* Mitral valve infections
* Redo surgery on the mitral valve

Where it's running

• CHU Saint-Etienne
  Saint-Etienne, France Recruiting

Study contacts

• Principal investigator: Andranik PETROSYAN, MD — Centre Hospitalier Universitaire de Saint Etienne
• Study coordinator: Andranik PETROSYAN, MD
• Email: andranik.petrosyan@chu-st-etienne.fr
• Phone: (0)477829505

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Using the CoolCryo System to treat Atrial Fibrillation during Mitral Valve Surgery

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.