Examining the effects of frailty and ICU-acquired weakness on fatigue after ICU discharge
Official title: Impact of Frailty and ICU-AW on Post-ICU Fatigue Self-reported
Run by Centre Hospitalier Universitaire de Saint Etienne · NCT05984069 · Data updated 2026-11-12
This study is trying to see how being weak from a long stay in the ICU affects tiredness after leaving the hospital for people who have been in the ICU for a while.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | Centre Hospitalier Universitaire de Saint Etienne Academic / other |
| Locations | 2 sites (Saint-Etienne and 1 other locations) |
| Status | Recruiting |
| Started | July 1, 2022 |
| Main results expected | December 2025 |
| Study ends | December 2025 |
| Registry record updated | March 18, 2025 |
| Trial ID | NCT05984069 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients who have had a prolonged stay in the ICU or have required mechanical ventilation.
✕Probably not a fit
Patients scheduled for surgery with ICU admission, pregnant individuals, or those under guardianship may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to explore the relationship between frailty, ICU-acquired weakness (ICU-AW), and self-reported fatigue in patients who have experienced prolonged stays in the Intensive Care Unit (ICU). By collecting prospective data from patients who have been in the ICU for at least 7 days or on mechanical ventilation for 5 days, the study seeks to identify risk factors associated with post-ICU fatigue. The findings could help in understanding how frailty impacts recovery and fatigue levels after ICU discharge, potentially leading to improved patient care strategies.
Why it matters
Potential benefit: If successful, this study could provide insights that lead to better management of fatigue in post-ICU patients, enhancing their recovery and quality of life.
How similar studies have gone: While the specific relationship between frailty and post-ICU fatigue is not extensively studied, related research on post-ICU syndrome has shown promising results in understanding patient recovery.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with a length of stay in intensive care \> or equal to 7 days, or mechanical ventilation \> or equal to 5 days Exclusion Criteria: * Scheduled surgery with admission in ICU * Pregnancy * Guardianship
Where it's running
-
Chu Saint-Etienne
Saint-Etienne, France Recruiting -
Hôpital Privé de la Loire
Saint-Etienne, France Recruiting
Study contacts
- Principal investigator: Jérôme MOREL, MD PhD — Centre Hospitalier Universitaire de Saint Etienne
- Study coordinator: Jérôme MOREL, MD PhD
- Email: jerome.morel@chu-st-etienne.fr
- Phone: (0)477828553
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.