Clinical trial Recruiting at 2 sites Observational Ages 18 and up

Examining the effects of frailty and ICU-acquired weakness on fatigue after ICU discharge

Official title: Impact of Frailty and ICU-AW on Post-ICU Fatigue Self-reported

Run by Centre Hospitalier Universitaire de Saint Etienne · NCT05984069 · Data updated 2026-11-12

This study is trying to see how being weak from a long stay in the ICU affects tiredness after leaving the hospital for people who have been in the ICU for a while.

More Post Intensive Care Syndrome (PICS) trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment150 (estimated)
SponsorCentre Hospitalier Universitaire de Saint Etienne
Academic / other
Locations2 sites (Saint-Etienne and 1 other locations)
StatusRecruiting
StartedJuly 1, 2022
Main results expectedDecember 2025
Study endsDecember 2025
Registry record updatedMarch 18, 2025
Trial IDNCT05984069 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients who have had a prolonged stay in the ICU or have required mechanical ventilation.

Probably not a fit

Patients scheduled for surgery with ICU admission, pregnant individuals, or those under guardianship may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the relationship between frailty, ICU-acquired weakness (ICU-AW), and self-reported fatigue in patients who have experienced prolonged stays in the Intensive Care Unit (ICU). By collecting prospective data from patients who have been in the ICU for at least 7 days or on mechanical ventilation for 5 days, the study seeks to identify risk factors associated with post-ICU fatigue. The findings could help in understanding how frailty impacts recovery and fatigue levels after ICU discharge, potentially leading to improved patient care strategies.

Why it matters

Potential benefit: If successful, this study could provide insights that lead to better management of fatigue in post-ICU patients, enhancing their recovery and quality of life.

How similar studies have gone: While the specific relationship between frailty and post-ICU fatigue is not extensively studied, related research on post-ICU syndrome has shown promising results in understanding patient recovery.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with a length of stay in intensive care \> or equal to 7 days, or mechanical ventilation \> or equal to 5 days

Exclusion Criteria:

* Scheduled surgery with admission in ICU
* Pregnancy
* Guardianship

Where it's running

  • Chu Saint-Etienne
    Saint-Etienne, France
    Recruiting
  • Hôpital Privé de la Loire
    Saint-Etienne, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.