Examining the effects of frailty and ICU-acquired weakness on fatigue after ICU discharge

Impact of Frailty and ICU-AW on Post-ICU Fatigue Self-reported

Observational Centre Hospitalier Universitaire de Saint Etienne · NCT05984069

This study is trying to see how being weak from a long stay in the ICU affects tiredness after leaving the hospital for people who have been in the ICU for a while.

Quick facts

Study typeObservational
Enrollment150 (estimated)
Ages18 Years and up
SexAll
SponsorCentre Hospitalier Universitaire de Saint Etienne Academic / other
Locations2 sites (Saint-Etienne and 1 other locations)
Trial IDNCT05984069 on ClinicalTrials.gov

What this trial studies

This observational study aims to explore the relationship between frailty, ICU-acquired weakness (ICU-AW), and self-reported fatigue in patients who have experienced prolonged stays in the Intensive Care Unit (ICU). By collecting prospective data from patients who have been in the ICU for at least 7 days or on mechanical ventilation for 5 days, the study seeks to identify risk factors associated with post-ICU fatigue. The findings could help in understanding how frailty impacts recovery and fatigue levels after ICU discharge, potentially leading to improved patient care strategies.

Who should consider this trial

Good fit: Ideal candidates for this study are patients who have had a prolonged stay in the ICU or have required mechanical ventilation.

Not a fit: Patients scheduled for surgery with ICU admission, pregnant individuals, or those under guardianship may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights that lead to better management of fatigue in post-ICU patients, enhancing their recovery and quality of life.

How similar studies have performed: While the specific relationship between frailty and post-ICU fatigue is not extensively studied, related research on post-ICU syndrome has shown promising results in understanding patient recovery.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with a length of stay in intensive care \> or equal to 7 days, or mechanical ventilation \> or equal to 5 days

Exclusion Criteria:

* Scheduled surgery with admission in ICU
* Pregnancy
* Guardianship

Where this trial is running

Saint-Etienne and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Post Intensive Care SyndromeIntensive Care UnitfrailtyfatigueICU acquired-weaknessFACIT-Fphysical activity
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.