Sleep extension to reduce performance loss from sleep deprivation

Effect of Sleep Extension in Prevention to Sleep Deprivation on Running Endurance Performance

Not applicable Interventional Centre Hospitalier Universitaire de Saint Etienne · NCT06928168

This trial tests whether adding extra sleep in the days before long runs helps healthy adult runners resist the fatigue and performance decline caused by partial or total sleep deprivation.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment69 (estimated)
Ages18 Years to 50 Years
SexAll
SponsorCentre Hospitalier Universitaire de Saint Etienne Academic / other
Locations1 site (Saint-Etienne)
Trial IDNCT06928168 on ClinicalTrials.gov

What this trial studies

Healthy adults who run regularly will follow a period of either their usual sleep or prescribed sleep extension in the days before a prolonged running exercise. Participants will then be exposed to partial or total sleep deprivation and complete endurance running tests while researchers record performance, rate of perceived exertion (RPE), and fatigue measures. The protocol explicitly examines reproducibility of effects and individual differences in resistance to sleep loss. Outcomes will compare whether prior sleep extension lessens the negative impact of sleep deprivation on sustained running performance.

Who should consider this trial

Good fit: Healthy men and women aged 18–50 who run at least one session longer than one hour per week, normally sleep 6–8 hours per night, have no chronic medical conditions, and are not shift workers or currently in competition.

Not a fit: People with chronic illnesses, night-shift workers, those with sleep disorders or excessive daytime sleepiness, or those whose usual sleep falls outside 6–8 hours may not be represented and therefore may not benefit from the results.

Why it matters

Potential benefit: If successful, this could provide a simple, low-risk strategy—getting extra sleep before events—to reduce fatigue and help preserve endurance performance during sleep-deprived competitions.

How similar studies have performed: Small prior studies suggest sleep extension before endurance events can reduce perceived exertion and partly protect performance under sleep loss, but published evidence is limited and reproducibility remains uncertain.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Volunteer who signed the written consent form.
* Man or woman.
* Aged 18-50.
* Physically active and running at least one session of more than one hour per week.
* Haven't participated in any competition in the month before the first visit.
* Not participating in any competition during the study.
* Usual sleep time between 6h-8h per night.

Exclusion Criteria:

* \- Any chronic pathology.
* Working night shift.
* Having sleep disorders: score \> 5 at Pittsburg Sleep Quality Index.
* Excessive sleepiness: score \>10 at Epworth Sleepiness scale.

Where this trial is running

Saint-Etienne

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HealthySleep deprivationSleep extensionEndurance runningFatigue
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.