Imaging and follow-up of pigmented tumors on the front of the eye in children
Imaging and Evolution of Pigmented Tumors of the Anterior Ocular System in Children
This project will use painless imaging to see if watching pigmented tumors on the front of the eye can guide follow-up and reduce unnecessary surgery for children under 18.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 53 (estimated) |
| Ages | N/A to 18 Years |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire de Saint Etienne Academic / other |
| Locations | 1 site (Saint-Etienne) |
| Trial ID | NCT07120178 on ClinicalTrials.gov |
What this trial studies
This is an observational programme using non-invasive ocular imaging to track pigmented anterior segment lesions in children. Participants undergo slit-lamp exams, dermatoscopy at ×20 and ×400, and confocal microscopy to document size, color and microscopic features over time. The goal is to use imaging changes to adapt follow-up schedules and avoid invasive excision when imaging shows no suspicious cells. All procedures are painless and intended to provide data to personalize monitoring and answer parents' questions about likely evolution.
Who should consider this trial
Good fit: Children under 18 seen at their first dermato-ophthalmological consultation who have a pigmented tumor of the anterior ocular system are the intended participants.
Not a fit: Patients who were over 18 at their first exam or those whose lesions already require immediate biopsy or treatment based on clinical findings are unlikely to benefit from a monitoring-focused approach.
Why it matters
Potential benefit: If successful, this approach could reduce unnecessary surgical excisions and allow more personalized, less invasive monitoring for children with conjunctival pigmented tumors.
How similar studies have performed: Non-invasive imaging of ocular pigmented lesions has been applied in adults and isolated pediatric reports exist, but comprehensive, systematic pediatric follow-up data are limited, so this approach is relatively untested in children.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient who had a first dermato-ophthalmological consultation \< 18 years old with pigmented tumors of the anterior ocular system Exclusion Criteria: * patient over 18 years old at first examination
Where this trial is running
Saint-Etienne
- CHU Saint-Etienne — Saint-Etienne, France (Recruiting)
Study contacts
- Principal investigator: Jean Luc PERROT, Md, PhD — Centre Hospitalier Universitaire de Saint Etienne
- Study coordinator: Jean Luc PERROT, Md, PhD
- Email: j.luc.perrot@chu-st-etienne.fr
- Phone: (0)477828508
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.