Imaging and follow-up of pigmented tumors on the front of the eye in children
Official title: Imaging and Evolution of Pigmented Tumors of the Anterior Ocular System in Children
Run by Centre Hospitalier Universitaire de Saint Etienne · NCT07120178 · Data updated 2026-11-12
This project will use painless imaging to see if watching pigmented tumors on the front of the eye can guide follow-up and reduce unnecessary surgery for children under 18.
Quick facts
| Study type | Observational |
|---|---|
| Ages | Any age to 18 Years |
| Sex | All |
| Enrollment | 53 (estimated) |
| Sponsor | Centre Hospitalier Universitaire de Saint Etienne Academic / other |
| Locations | 1 site (Saint-Etienne) |
| Status | Recruiting |
| Started | April 1, 2025 |
| Main results expected | December 2025 |
| Study ends | December 2025 |
| Registry record updated | August 13, 2025 |
| Trial ID | NCT07120178 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children under 18 seen at their first dermato-ophthalmological consultation who have a pigmented tumor of the anterior ocular system are the intended participants.
✕Probably not a fit
Patients who were over 18 at their first exam or those whose lesions already require immediate biopsy or treatment based on clinical findings are unlikely to benefit from a monitoring-focused approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an observational programme using non-invasive ocular imaging to track pigmented anterior segment lesions in children. Participants undergo slit-lamp exams, dermatoscopy at ×20 and ×400, and confocal microscopy to document size, color and microscopic features over time. The goal is to use imaging changes to adapt follow-up schedules and avoid invasive excision when imaging shows no suspicious cells. All procedures are painless and intended to provide data to personalize monitoring and answer parents' questions about likely evolution.
Why it matters
Potential benefit: If successful, this approach could reduce unnecessary surgical excisions and allow more personalized, less invasive monitoring for children with conjunctival pigmented tumors.
How similar studies have gone: Non-invasive imaging of ocular pigmented lesions has been applied in adults and isolated pediatric reports exist, but comprehensive, systematic pediatric follow-up data are limited, so this approach is relatively untested in children.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient who had a first dermato-ophthalmological consultation \< 18 years old with pigmented tumors of the anterior ocular system Exclusion Criteria: * patient over 18 years old at first examination
Where it's running
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CHU Saint-Etienne
Saint-Etienne, France Recruiting
Study contacts
- Principal investigator: Jean Luc PERROT, Md, PhD — Centre Hospitalier Universitaire de Saint Etienne
- Study coordinator: Jean Luc PERROT, Md, PhD
- Email: j.luc.perrot@chu-st-etienne.fr
- Phone: (0)477828508
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.