Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Combining physical activity and education for patients with chronic Lyme disease symptoms

Official title: Effectiveness of an Intervention Combining Adapted Physical Activity and Therapeutic Education in Patients With Chronic Symptoms Attributed to Lyme Borreliosis. Multicenter, Controlled, Randomized Pilot Study

Run by Centre Hospitalier Universitaire de Saint Etienne · NCT05641116 · Data updated 2026-11-12

This study tests whether a program that combines exercise and education can help people with chronic Lyme disease symptoms feel better.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment62 (estimated)
SponsorCentre Hospitalier Universitaire de Saint Etienne
Academic / other
Locations2 sites (Clermont-Ferrand and 1 other locations)
StatusRecruiting
StartedSeptember 14, 2023
Main results expectedDecember 2026
Study endsDecember 2027
Registry record updatedOctober 2, 2026
Trial IDNCT05641116 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients with chronic Lyme disease symptoms lasting more than six months who engage in less than 150 minutes of physical activity per week.

Probably not a fit

Patients with significant cardiac, respiratory, or joint comorbidities that prevent safe participation in physical activity may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of a program that integrates adapted physical activity with therapeutic education for patients suffering from chronic symptoms related to Lyme borreliosis. The intervention aims to improve patient management through a multidisciplinary approach, addressing both physical activity levels and educational support. Patients will be assessed for their symptoms and physical activity habits, and those who meet the criteria will participate in a structured program designed to enhance their overall well-being.

Why it matters

Potential benefit: If successful, this intervention could significantly improve the quality of life and functional outcomes for patients with chronic Lyme disease symptoms.

How similar studies have gone: Other studies have shown promise in using physical activity and educational interventions for chronic conditions, suggesting potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient referred to the reference center for tick-borne diseases by his attending physician
* Duration of symptoms \>6 months
* At the end of the initial assessment, the diagnosis of functional somatic disorders is retained after consensus between the physicians
* Patient practicing less than 150 minutes of regular physical activity per week (WHO recommendations)

Exclusion Criteria:

* Patients with cardiac or respiratory pathologies that contraindicate the practice of physical activity physical activity
* Important comorbidities contraindicating the practice of physical activity: associated cardiac pathologies associated cardiac pathologies (severe rhythm disorders such as rapid atrial fibrillation), respiratory pathologies respiratory pathologies (obstructive or severe restrictive respiratory insufficiency), disabling joint pathologies joint pathologies (gonarthrosis or coxarthrosis limiting training on a treadmill or on a high-intensity bicycle). intensity cycling).
* Patients under guardianship or curatorship

Where it's running

  • Chu Saint Etienne
    Saint-Etienne, France
    Recruiting
  • CHU Clermont-Ferrand
    Clermont-Ferrand, France
    Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.