Combining physical activity and education for patients with chronic Lyme disease symptoms
Official title: Effectiveness of an Intervention Combining Adapted Physical Activity and Therapeutic Education in Patients With Chronic Symptoms Attributed to Lyme Borreliosis. Multicenter, Controlled, Randomized Pilot Study
Run by Centre Hospitalier Universitaire de Saint Etienne · NCT05641116 · Data updated 2026-11-12
This study tests whether a program that combines exercise and education can help people with chronic Lyme disease symptoms feel better.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 62 (estimated) |
| Sponsor | Centre Hospitalier Universitaire de Saint Etienne Academic / other |
| Locations | 2 sites (Clermont-Ferrand and 1 other locations) |
| Status | Recruiting |
| Started | September 14, 2023 |
| Main results expected | December 2026 |
| Study ends | December 2027 |
| Registry record updated | October 2, 2026 |
| Trial ID | NCT05641116 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients with chronic Lyme disease symptoms lasting more than six months who engage in less than 150 minutes of physical activity per week.
✕Probably not a fit
Patients with significant cardiac, respiratory, or joint comorbidities that prevent safe participation in physical activity may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of a program that integrates adapted physical activity with therapeutic education for patients suffering from chronic symptoms related to Lyme borreliosis. The intervention aims to improve patient management through a multidisciplinary approach, addressing both physical activity levels and educational support. Patients will be assessed for their symptoms and physical activity habits, and those who meet the criteria will participate in a structured program designed to enhance their overall well-being.
Why it matters
Potential benefit: If successful, this intervention could significantly improve the quality of life and functional outcomes for patients with chronic Lyme disease symptoms.
How similar studies have gone: Other studies have shown promise in using physical activity and educational interventions for chronic conditions, suggesting potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient referred to the reference center for tick-borne diseases by his attending physician * Duration of symptoms \>6 months * At the end of the initial assessment, the diagnosis of functional somatic disorders is retained after consensus between the physicians * Patient practicing less than 150 minutes of regular physical activity per week (WHO recommendations) Exclusion Criteria: * Patients with cardiac or respiratory pathologies that contraindicate the practice of physical activity physical activity * Important comorbidities contraindicating the practice of physical activity: associated cardiac pathologies associated cardiac pathologies (severe rhythm disorders such as rapid atrial fibrillation), respiratory pathologies respiratory pathologies (obstructive or severe restrictive respiratory insufficiency), disabling joint pathologies joint pathologies (gonarthrosis or coxarthrosis limiting training on a treadmill or on a high-intensity bicycle). intensity cycling). * Patients under guardianship or curatorship
Where it's running
-
Chu Saint Etienne
Saint-Etienne, France Recruiting -
CHU Clermont-Ferrand
Clermont-Ferrand, France Not yet recruiting
Study contacts
- Principal investigator: David HUPIN, MD — CHU de Saint Etienne
- Study coordinator: David HUPIN, MD
- Email: David.Hupin@chu-st-etienne.fr
- Phone: 0477828413
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.