Condition

Exercise Training clinical trials and research

• 22Clinical trials
• 37NIH research projects
• 1New in 30 days
• 12Countries

Newest Exercise Training clinical trials

All recruiting trials (22)

• Outdoor resistance training for older adults

  This trial tests a 6-week outdoor strength program using benches and a smartphone app to see if it’s safe, usable, and appealing for community-dwelling adults aged 65 and older.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven, Vlaams-Brabant · NCT07928687

• Olive leaf extract plus endurance training to boost muscle performance in healthy adults

  This study tests whether taking olive leaf extract while doing endurance training helps healthy adults improve their exercise performance more than training with a placebo.

  Recruiting University of Lausanne · Lausanne · NCT07729072

• Eccentric Hamstring Training vs Sprint-Specific Training for Hamstring Performance in Young Athletes

  This study tests whether three hamstring training approaches (eccentric, sprint-based, and Romanian deadlift with Nordic hamstring) improve hamstring structure and sprint-related performance in healthy young athletes.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07716319

• Enhanced Music and Natural Visuals for Emotional Health

  This trial tests whether using soundBrilliance software with music and natural visuals helps improve emotional health for people 13 and older.

  Recruiting at 3 sites soundBrilliance LLC · Fort Collins, Colorado and 2 other locations · NCT07676110

• Visual feedback in inspiratory muscle training after lobectomy

  This study tests whether adding a mobile app with visual feedback to inspiratory muscle training helps lung cancer patients after lobectomy by improving motivation, adherence, and comfort while breathing.

  Recruiting Hacettepe University · Ankara, Altındağ · NCT07646288

• Estrogen and Exercise to Build Muscle in Postmenopausal Women

  Postmenopausal women will try a 12-week exercise program while receiving estrogen or placebo to see if estrogen helps build muscle.

  Recruiting University of Aarhus · Aarhus, Jutland · NCT07617454

• Right‑side heart response to exercise in people with COPD

  This project will test how the right side of the heart responds to moderate and high‑intensity exercise in adults 40 and older with COPD and whether a targeted moderate‑intensity cycling program can improve that response.

  Recruiting University of Colorado, Denver · Aurora, Colorado · NCT07576894

• Pain and moderate exercise in midlife former athletes, masters athletes, and nonathletes

  This trial tests if moderate-intensity strength versus aerobic exercise changes pain before and after workouts in adults aged 35–65 who are former competitive athletes, current master's athletes, or nonathletes.

  Recruiting Marquette University · Milwaukee, Wisconsin · NCT07502742

• Powered lower-limb exoskeleton training for adults with prolonged mechanical ventilation

  We are testing whether using a powered leg exoskeleton during training can improve leg strength, breathing measures, and recovery time for people who have been on a ventilator for a long period.

  Recruiting Fu Jen Catholic University · New Taipei City · NCT07445035

• Exercise with laser-pointer visual feedback for balance in Parkinson's

  We will try adding laser-pointer visual feedback exercises to standard physiotherapy for people with mild-to-moderate Parkinson's to see if balance and mobility improve.

  Recruiting Hasan Kalyoncu University · Gaziantep, Şahinbey · NCT07322939

• Adaptive AI Coaching to Boost Indoor Cycling Performance

  This study tests whether an adaptive, AI-powered coaching system that uses real-time data can help 18- to 40-year-olds ride harder during a 20-minute indoor cycling test.

  Recruiting University of Miami · Coral Gables, Florida · NCT07318233

• Exercise training and the immune response in lung cancer

  This study tests whether a 12-week moderate or high-intensity exercise program can change the immune markers in people with non-small cell or small cell lung cancer who are receiving standard care.

  Recruiting Medical University of Graz · Graz · NCT07267000

• Keeping up with home exercises for musculoskeletal conditions

  This project will see how well adults with musculoskeletal conditions stick to personalized home exercise programs and which clinical, psychological, or demographic factors relate to sticking with them.

  Recruiting Konya Beyhekim Training and Research Hospital · Konya, Konya · NCT07261553

• Breathing muscle training plus dietary nitrate to improve exercise at simulated moderate altitude

  This project tests whether breathing muscle training and beetroot-derived nitrate help healthy, active adults exercise better under simulated moderate-altitude (low-oxygen) conditions.

  Recruiting Embry-Riddle Aeronautical University · Daytona Beach, Florida · NCT07216755

• Predicting who improves after phase II cardiac rehabilitation for reduced ejection fraction

  This project will test whether blood microRNA patterns together with non-invasive exercise measurements can predict which people with reduced ejection fraction heart failure will improve their peak oxygen uptake after a phase II cardiac rehab program.

  Recruiting Centre Hospitalier de Corbie · Corbie · NCT07164911

• Moderate-intensity aerobic and resistance exercise to reduce pain sensitization in breast cancer survivors

  This program will try a supervised moderate-intensity aerobic plus resistance exercise regimen to see if it reduces pain sensitization and persistent upper-limb pain in breast cancer survivors.

  Recruiting Universidad Rey Juan Carlos · Madrid · NCT07128030

• Orthosis and Exercise for Grade 1–2 Spondylolisthesis

  This study tests whether stabilization exercise, conventional exercise, or wearing an orthosis can improve pain, physical function, and quality of life in adults with mild spondylolisthesis.

  Recruiting Medipol University · Istanbul, Istanbul · NCT06989138

• Understanding how resistance training affects muscle growth and fitness

  This study is testing how resistance training affects muscle growth and fitness in healthy people to see what factors might help them get better results.

  Recruiting University of Jyvaskyla · Jyväskylä, Central Finland · NCT06573086

• Robotic stationary‑bike balance training to improve older adults' cycling skills

  This study will try 20 short sessions on a robotic stationary bike that gives controlled, unexpected balance challenges to see if it helps people aged 65 and older ride more safely.

  Recruiting at 2 sites University of Erlangen-Nürnberg Medical School · Nuremberg, Bavaria and 1 other locations · NCT06453473

• Home-based exercise program for kidney transplant recipients

  This study is testing whether a home-based exercise program can help kidney transplant recipients improve their fitness and overall health compared to different levels of exercise intensity.

  Recruiting at 2 sites KU Leuven · Ghent and 1 other locations · NCT06260579

• Using guided imagery to boost exercise adherence and support healthy aging

  This study tests if using guided imagery can help middle-aged adults stick to their exercise routines and feel more positive about working out.

  Recruiting University of Kansas Medical Center · Kansas City, Kansas · NCT06123182

• Understanding heart function in COPD patients through exercise and imaging

  This study is testing how exercise affects heart function in people with COPD to see if it can help us understand their heart health better.

  Recruiting University of Colorado, Denver · Aurora, Colorado · NCT05896579

NIH-funded research (37)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Resistance Exercise Training for Blood Pressure and Blood Vessel Health in Middle-Aged Women

  A large study will test whether 16 weeks of supervised resistance exercise can lower blood pressure and improve blood vessel health in women aged 40–64 with high blood pressure.

  NIH research Univ of Maryland, College Park · College Park, United States · NIH-11448163

• Time-of-day exercise and social jetlag: protecting the heart and metabolic health

  A study to see if misaligned daily schedules (social jetlag) reduce the benefits of exercise on heart and metabolic health in adults.

  NIH research University of Nevada Las Vegas · Las Vegas, United States · NIH-11386467

• Intranasal insulin plus exercise to protect brain health in adults with type 2 diabetes

  A small study will test whether combining inhaled insulin with aerobic exercise can improve brain blood flow, insulin signaling in the brain, and thinking skills in adults with type 2 diabetes.

  NIH research Rutgers, the State Univ of N.j. · Piscataway, United States · NIH-11358832

• High-intensity exercise to improve language after stroke

  This project looks at whether a tailored high-intensity exercise program can help people with aphasia after stroke improve their speaking, thinking, and well-being.

  NIH research University of California Berkeley · Berkeley, United States · NIH-11332836

• Exercise training for people with heart failure with preserved ejection fraction (HFpEF)

  This project tests whether blocking specific muscle nerve signals with a spinal fentanyl injection changes circulation, muscle fatigue, and exercise ability in people with HFpEF compared with healthy controls.

  NIH research VA Salt Lake City Healthcare System · Salt Lake City, United States · NIH-11329777

• Cognitive-behavioral therapy then exercise to lower type 2 diabetes risk in teenage girls

  Teen girls at risk for type 2 diabetes will try short-term talking therapy first, then structured exercise, to help lift mood, increase activity, and lower diabetes risk.

  NIH research Colorado State University · Fort Collins, United States · NIH-11324577

• Live online exercise program for wheelchair users

  This project uses live, home-based exercise sessions over videoconference to try to improve heart and metabolic health for adults who use wheelchairs.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11262934

• How exercise changes under-the-skin fat to help blood sugar control

  This research looks at how exercise-related changes in the fat beneath the skin can improve blood sugar control for people with adult-onset (type 2) diabetes and related metabolic conditions.

  NIH research Joslin Diabetes Center · Boston, United States · NIH-11257707

• Exercise and biological samples to understand alcohol-related liver disease

  A patient-focused program from Cleveland Clinic aims to study alcohol-related liver disease by collecting blood, urine, saliva, and PBMC samples from patients and from heavy drinkers and healthy controls.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11232483

• Resistance training to protect muscle in older adults with obesity taking GLP-1 receptor agonists

  Older adults with obesity who start GLP-1 receptor agonists may lose muscle; this study tests whether a progressive resistance training program can preserve muscle and keep strength up.

  NIH research University of Florida · Gainesville, United States · NIH-11209896

• Tailored exercise plus NAD+ supplement to rebuild muscle and fitness in adolescent and young adult stem-cell transplant survivors

  This project tests whether a personalized home exercise program combined with an NAD+ precursor supplement helps teenage and young adult stem-cell transplant survivors regain muscle mass and fitness.

  NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-11176198

• How exercise-released molecules affect blood vessel and brain blood flow with aging in men and women

  We will see whether a 12-week aerobic exercise program changes blood vessel health and brain blood flow in younger, middle-aged, and older men and women and whether exercise-released molecules (exerkines) explain differences in response.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11170760

• Improving thinking and memory in breast cancer survivors with community aerobic exercise

  This project uses community-based aerobic exercise to help women 50+ who survived breast cancer improve thinking, memory, and brain health.

  NIH research Mayo Clinic Arizona · Scottsdale, United States · NIH-11136886

• How exercise timing and social jetlag affect heart and metabolic health

  This project looks at whether mismatched weekday/weekend sleep schedules change how the timing of exercise helps protect heart and metabolic health for people at risk of cardiovascular and metabolic problems.

  NIH research University of Nevada Las Vegas · Las Vegas, United States · NIH-11135579

• Understanding how aging and exercise affect fat within muscles

  This project looks at how fat marbled within our muscles changes with age and exercise, and how it might contribute to conditions like type 2 diabetes and muscle weakness.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11115647

• Effects of high-intensity exercise on language recovery after stroke

  This study is looking at how doing high-energy exercise can help people who have had a stroke and struggle with language skills, aiming to improve their speaking and thinking abilities while they recover.

  NIH research University of California Berkeley · Berkeley, United States · NIH-11106862

• Personalized exercise training to enhance physical ability in older adults with cardiac amyloidosis

  This study is looking to see if a special 12-week exercise program can help older adults with heart issues from cardiac transthyretin amyloidosis feel stronger and improve their overall quality of life.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11072081

• Combining therapy and exercise to prevent type 2 diabetes in at-risk teens

  This study is looking at how combining therapy to improve mental health with exercise can help young girls at risk for type 2 diabetes feel better and stay active, especially those from less advantaged backgrounds.

  NIH research Colorado State University · Fort Collins, United States · NIH-11059156

• Investigating heart health and exercise in people with HIV

  This study is looking at how being less fit and having trouble increasing your heart rate can impact heart health for people living with HIV, and it will explore how exercise might help improve heart function and overall fitness.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11045688

• Finding protein markers that show how exercise helps heart failure patients

  This study is looking at how exercise can help people with heart failure by checking for changes in certain proteins in their blood before and after they start an exercise program, so we can find better ways to help them feel better and recover.

  NIH research Stanford University · Stanford, United States · NIH-11042809

• Investigating how telehealth exercise training affects heart and metabolic health in wheelchair users

  This study is testing a fun exercise program that you can do from your wheelchair at home, using music to help improve your heart and overall health, and it's designed for people who are at risk for health issues because they don't move around much.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11037937

• Understanding how resistance exercise improves insulin sensitivity in diabetes

  This study is looking at how strength training can help people with type 2 diabetes build muscle and improve how their bodies use insulin, so if you join, you'll get to work out while we learn more about how these exercises can benefit your health!

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11030575

• How exercise affects blood vessel health as we age

  This study is looking at how regular aerobic exercise can help keep blood vessels healthy as we get older, and it’s for both younger and older adults, including men and women, who will take part in a 12-week exercise program to see how their vascular health changes.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-10978109

• Effects of exercise training on heart failure with preserved ejection fraction

  This study is looking at how exercise can help people with heart failure feel better and be more active by understanding how certain nerves affect blood flow and tiredness during workouts, so we can create better exercise plans just for them.

  NIH research VA Salt Lake City Healthcare System · Salt Lake City, United States · NIH-10938020

• How exercise affects blood clots and oxygen levels in veterans recovering from COVID-19

  This study is looking at how exercise can help veterans who are dealing with lingering health issues after COVID-19 by improving their blood flow, oxygen levels in their tissues, and overall cell health.

  NIH research Baltimore VA Medical Center · Baltimore, United States · NIH-10927076

• Improving muscle mass and fitness in young cancer survivors through exercise and supplements

  This study is designed to help young people who have had stem cell transplants stay strong and healthy by combining personalized exercise programs with special supplements, making it easier for them to keep their muscle and fitness levels up at home.

  NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-10914104

• Using exercise to lower heart disease risk in men receiving hormone therapy for prostate cancer

  This study is looking at how exercise can help men with prostate cancer who are receiving hormone therapy stay healthier and lower their chances of heart problems, by testing easy home workout programs that can improve their fitness and heart health.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-10913604

• How exercise timing affects heart health in people with social jetlag

  This study is looking at how changing sleep schedules, like those caused by work or school, affects how our bodies respond to exercise, and it wants to find out if working out at different times of the day can help improve heart health for people dealing with these sleep changes.

  NIH research University of Nevada Las Vegas · Las Vegas, United States · NIH-10899491

• Exercise training for patients with multiple myeloma before stem cell transplantation

  This study is looking at how an 8-week home exercise program can help people with multiple myeloma feel stronger and healthier while getting ready for a stem cell transplant, with virtual support to guide them along the way.

  NIH research Boston University (Charles River Campus) · Boston, United States · NIH-10898403

• Evaluating how exercise training affects heart health in heart failure patients using advanced imaging techniques.

  This study is looking at how exercise can help improve heart health in people with heart failure by using special imaging to see changes in the heart while they do aerobic workouts, so we can better understand how to tailor exercise programs for each person.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-10848235

• How gut bacteria affect exercise response in breast cancer survivors

  This study is looking at how the bacteria in your gut might affect how you feel during exercise if you're a breast cancer survivor dealing with fatigue, and it involves a 12-week workout program to see if getting active can help you feel better.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-10844505

• Exploring exercise training for wheelchair users with multiple sclerosis

  This study is testing a special home-based exercise program for people with multiple sclerosis who use wheelchairs, to see if it can help improve their health and meet their unique needs.

  NIH research University of Texas Hlth Sci Ctr Houston · Houston, United States · NIH-10810803

• Using NAD+ supplements and exercise to boost fitness in Friedreich's Ataxia

  This study is looking at whether taking NAD+ supplements along with exercise can help people with Friedreich's Ataxia breathe better and have more energy for daily activities.

  NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-10756492

• Using MitoQ to improve exercise effects on blood vessel function in older women

  This study is looking at whether taking a daily supplement called MitoQ while doing moderate exercise can help improve blood vessel health in postmenopausal women, offering a potential alternative to hormone therapy for better heart health.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-10686453

• How exercise affects brain signals that control metabolism and energy balance

  This study is looking at how exercise helps our bodies manage sugar and weight by exploring how signals from the brain and body work together, and it's aimed at finding new ways to help people with metabolic issues.

  NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-10677755

• Improving brain function in breast cancer survivors through exercise

  This study is looking at how joining a community exercise program can help improve thinking and memory skills for women over 50 who have survived breast cancer, especially since they may experience some mental decline after treatment.

  NIH research Mayo Clinic Arizona · Scottsdale, United States · NIH-10625291

• Comparing heat therapy and exercise for lowering high blood pressure

  This study is looking at whether using heat therapy, like saunas, can help lower high blood pressure just as well as regular exercise, and it's for adults who might find it hard to exercise for different reasons.

  NIH research University of Oregon · Eugene, United States · NIH-10199776

Related topics

Quick answers

How many Exercise Training clinical trials are recruiting right now?

22, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 12 countries. The most sites are in United States (8 trials), Turkey (Türkiye) (4 trials), Belgium (2 trials), Germany (1 trial), Israel (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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