Moderate-intensity aerobic and resistance exercise to reduce pain sensitization in breast cancer survivors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a supervised, combined moderate-intensity aerobic and resistance training program aimed at reducing pain sensitization in women who completed treatment for stage I–III breast cancer at least six months earlier and who report persistent upper-quadrant pain. The primary goals are to test feasibility, safety, and acceptability of the exercise intervention. Secondary measures include changes in pain intensity, somatosensory sensitivity, and temporal summation using quantitative sensory testing, while tertiary outcomes track quality of life and functional capacity. The intervention is delivered at Universidad Rey Juan Carlos with clinical collaboration from Hospital General Universitario Gregorio Marañón in Madrid.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult women diagnosed with stage I-III breast cancer
* Completion of active treatment (surgery, chemotherapy, and/or radiotherapy) at least 6 months prior to enrollment
* Presence of persistent pain or altered sensation in the upper quadrant of the affected limb related to oncologic treatment

Exclusion Criteria:

* Bilateral breast cancer
* Locoregional recurrence
* Other malignancies
* Pre-existing pain not related to cancer treatment
* Neurological or cognitive disorders
* Non-Spanish speakers
* Contraindications to moderate-intensity physical activity

Where it's running

• Universidad Rey Juan Carlos
  Madrid, Spain Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.