Exercise training for patients with multiple myeloma before stem cell transplantation
Official title: Prehabilitation Exercise Training in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation
Funded at Boston University (Charles River Campus) · NIH-10898403 · Data updated 2026-11-12
This study is looking at how an 8-week home exercise program can help people with multiple myeloma feel stronger and healthier while getting ready for a stem cell transplant, with virtual support to guide them along the way.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University (Charles River Campus) NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $38,648 |
| NIH project number | 1F31CA290730-01 |
| Project ID | NIH-10898403 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with multiple myeloma who are scheduled to undergo autologous stem cell transplantation.
✕Less likely to help
Patients who are not diagnosed with multiple myeloma or those who are not eligible for autologous stem cell transplantation may not benefit from this research.
What this research studies
This research investigates the impact of an 8-week home-based exercise program on patients with multiple myeloma who are preparing for autologous stem cell transplantation. The program is designed to improve muscle strength and overall health outcomes through virtually supervised sessions. By focusing on enhancing physical fitness and reducing the symptom burden associated with cancer treatment, the study aims to provide a supportive intervention that can lead to better clinical outcomes for patients. Participants will be monitored for changes in physical capacity, patient-reported outcomes, and cardiometabolic health.
Why it matters
Potential benefit: If successful, this research could lead to improved physical fitness and health outcomes for patients undergoing treatment for multiple myeloma.
How similar studies have gone: Previous research has shown that exercise interventions can improve outcomes for cancer patients, suggesting that this approach may be beneficial for multiple myeloma patients as well.
Where this research is happening
-
Boston University (Charles River Campus)
Boston, United States Active
Researchers
- Principal investigator: Normann, Amber — Boston University (Charles River Campus)
- Study coordinator: Normann, Amber
Related research
Other NIH-funded projects on the same topics.
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Integrative study of multiple myeloma genetics and disease biology
A team at Dana-Farber and partners is pursuing a long-term project to understand the genetic and molecular drivers of multiple myeloma and how treatments interact with disease biology.
-
Comparative Modeling to Prevent, Detect Early, and Treat Multiple Myeloma
A research team will build and compare computer models to understand how multiple myeloma develops, can be detected earlier, and treated more effectively.
-
How LDL Affects Multiple Myeloma: New Pathways to Keep Remission
A new grant is studying how cholesterol from LDL particles fuels multiple myeloma and how this interaction influences the tumor environment and immune response, with goals to help patients stay in remission.
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Therapy-induced senescence and immune activation in multiple myeloma
A study in people with multiple myeloma will explore how treatment-related senescence in cancer cells may stimulate the immune system and affect cancer return after standard frontline therapy.
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BCMA CAR-T enteritis: understanding immune toxicities in multiple myeloma
A broad study to uncover why some CAR-T cell treatments targeting BCMA cause severe intestinal inflammation in people with multiple myeloma.
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Understanding Drug-Resistant Multiple Myeloma to Stop Relapse
Researchers are studying why some myeloma cells resist treatment and how to create new therapies to prevent relapse.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.