Condition

Aerobic Exercise clinical trials and research

• 15Clinical trials
• 38NIH research projects
• 1New in 30 days
• 5Countries

Newest Aerobic Exercise clinical trials

All recruiting trials (15)

• Comparison of Different Exercise Protocols for Lipedema

  This study tests whether high‑intensity interval training or moderate‑intensity continuous training improves function, strength, and quality of life in adults with lipedema.

  Recruiting Hitit University · Çorum · NCT07873541

• Progressive Neuromuscular Stabilization vs. Aerobic Exercise for Obesity in Children

  This study tests whether technology-assisted progressive neuromuscular stabilization exercises can improve body composition and balance in children with obesity, compared with standard aerobic exercise.

  Recruiting Istanbul University - Cerrahpasa · Istanbul · NCT07744022

• Aerobic exercise and guided imagery for bowel problems after rectal cancer surgery

  This study tests whether a program of aerobic exercise plus guided imagery helps people with low anterior resection syndrome after rectal cancer surgery.

  Recruiting Biruni University · Istanbul · NCT07732894

• Downhill walking training for type 2 diabetes

  Researchers compare 8 weeks of downhill walking to level-ground walking in adults with type 2 diabetes to see which more improves walking ability and muscle and heart responses.

  Recruiting Acibadem University · Istanbul, Maltepe · NCT07693296

• Pain and moderate exercise in midlife former athletes, masters athletes, and nonathletes

  This trial tests if moderate-intensity strength versus aerobic exercise changes pain before and after workouts in adults aged 35–65 who are former competitive athletes, current master's athletes, or nonathletes.

  Recruiting Marquette University · Milwaukee, Wisconsin · NCT07502742

• Aerobic exercise to reduce heart risk in people with rheumatoid arthritis or chronic kidney disease

  This program will test whether a six-week individualized aerobic exercise plan can lower heart-related risk in people with rheumatoid arthritis or stage III–IV chronic kidney disease.

  Recruiting University of Franche-Comté · Besançon · NCT07469540

• Aerobic exercise during immune checkpoint inhibitor therapy for early-stage triple-negative breast cancer

  This study will test whether a supervised aerobic exercise program helps people with early-stage triple-negative breast cancer who are receiving immune checkpoint inhibitor therapy before surgery.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT07216495

• Combined upper-body resistance and aerobic exercise program for people treated for breast cancer

  This program will test whether a combined upper-body resistance and aerobic exercise routine helps people at least 15 months after breast cancer surgery improve arm function, strength, and symptoms.

  Recruiting Hacettepe University · Ankara, State · NCT07070791

• Upper-arm aerobic exercise for arterial stiffness in women treated for breast cancer.

  This trial will test whether an upper-extremity aerobic exercise program can reduce arterial stiffness in women aged 40–69 who are at least 15 months after breast cancer surgery and are currently physically inactive.

  Recruiting Hacettepe University · Ankara, State · NCT07070778

• Whole-body vibration therapy for adults with type 2 diabetes

  This trial tests whether whole-body vibration therapy, compared with aerobic exercise, can improve muscle oxygenation, vibration sense, balance, and physical capacity in adults with type 2 diabetes.

  Recruiting Ankara Medipol University · Ankara, Çankaya · NCT07002125

• Effects of aerobic exercise with music on medical students' mental health

  This study tests if an 8-week aerobic exercise program with music can help medical students in China feel less stressed and improve their focus and thinking skills.

  Recruiting Universiti Sains Malaysia · Yancheng, Jiangsu · NCT06788106

• Aerobic exercise to improve sensory, muscle, and psychosocial symptoms in women with migraine

  This trial will test whether supervised aerobic exercise plus one pain neuroscience education session helps women aged 18–48 with migraine reduce disability and improve sensory, musculoskeletal, and psychosocial symptoms.

  Recruiting University of Sao Paulo · Ribeirão Preto, São Paulo · NCT06716489

• Impact of MIND Diet and Aerobic Training on Cognition in Black Adults with High Blood Pressure

  This study is testing if following a special diet and doing aerobic exercise can help improve thinking skills and health in Black adults with high blood pressure.

  Recruiting Indiana University · Indianapolis, Indiana · NCT06152614

• Improving concussion recovery with high dose exercise

  This study is testing if a special exercise program can help teenagers recover faster from concussions and feel better sooner.

  Recruiting at 3 sites Phase 1/2 University of Colorado, Denver · Aurora, Colorado and 2 other locations · NCT05434130

• Effects of exercise timing on memory in young adults

  This study tests how exercising at different times of the day affects memory in healthy young adults aged 18-25.

  Recruiting University of North Carolina, Greensboro · Greensboro, North Carolina · NCT04861818

NIH-funded research (38)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Aerobic exercise to boost stroke rehabilitation outcomes with a VR game

  A VA-based study tests whether an aerobic workout before a hand-rehabilitation game can improve recovery after stroke for veterans.

  NIH research Ralph H Johnson VA Medical Center · Charleston, United States · NIH-11493622

• Community-based aerobic exercise for adults with moderate to severe traumatic brain injury

  A year-long aerobic exercise program is being tested to see if it can improve thinking, mood, and quality of life for adults aged 45–80 who have had moderate to severe traumatic brain injury.

  NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11448198

• Adaptive aerobic exercise plans during chemotherapy for colon cancer

  This study tests personalized aerobic exercise during chemotherapy for people with colon cancer to help them stay on their planned treatment schedule and reduce side effects.

  NIH research Adventhealth Orlando · Orlando, United States · NIH-11419227

• How bones respond to the body’s demand during aerobic exercise

  This grant explores how bone changes when we exercise aerobically, like running or cycling, to help people understand how to protect bone health.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11417943

• Understanding how aerobic exercise helps advanced Parkinson’s disease patients

  A study will test whether long-term high-intensity aerobic exercise improves motor and thinking abilities in people with advanced Parkinson’s disease who have deep brain stimulation, and will explore what brain changes accompany any benefits.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11414875

• Combining rTMS and aerobic exercise to help post-stroke depression and walking

  A new approach tests whether adding aerobic exercise to rTMS can reduce depression after stroke and improve walking.

  NIH research Medical University of South Carolina · Charleston, United States · NIH-11402238

• Adaptive aerobic exercise during colon cancer chemotherapy

  This program uses tailored aerobic exercise during chemotherapy to help people with stage II–III colon cancer complete their chemo doses and reduce side effects.

  NIH research Adventhealth Orlando · Orlando, United States · NIH-11350996

• How aerobic exercise affects muscle health in colon cancer survivors

  This study is looking at how a regular exercise program can help improve muscle health and strength in people who have survived colon cancer, with the goal of boosting their overall well-being and lowering the chances of cancer coming back.

  NIH research Adventhealth Orlando · Orlando, United States · NIH-11317318

• Breathing-strength training to lower blood pressure and help blood vessel health in postmenopausal women

  This compares a short daily high-resistance breathing exercise to standard aerobic workouts to help lower blood pressure and improve blood vessel health in postmenopausal women.

  NIH research University of Colorado · Boulder, UNITED STATES · NIH-11310122

• Home-based aerobic exercise plus online brain training to improve thinking after a first schizophrenia episode

  This program combines guided aerobic exercise with web-based cognitive training delivered by telehealth to help thinking and daily functioning for people after a first schizophrenia episode.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11306042

• Why people with diabetes get less benefit from aerobic exercise

  This project explores why people with diabetes often gain less cardiorespiratory fitness from aerobic exercise and looks for ways to help their muscles adapt better.

  NIH research Virginia Polytechnic Inst and St Univ · Blacksburg, United States · NIH-11297253

• Aerobic exercise plus targeted speech exercises to improve reading after stroke

  Short bouts of aerobic exercise done before focused speech-based reading work may help people with post-stroke aphasia read more accurately and regain independence.

  NIH research Kessler Foundation, INC. · East Hanover, UNITED STATES · NIH-11285474

• How genes and aerobic exercise might slow Parkinson's

  This project sees whether high-intensity aerobic exercise in community programs can slow Parkinson's disease and whether people’s genes affect those benefits.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11258046

• How aerobic exercise may help brain health and thinking after late-life depression

  This work looks at whether regular aerobic exercise can improve brain health and thinking in older adults who have recovered from late-life depression.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11235908

• Improving energy and strength in Veterans with chronic kidney disease using flywheel resistance plus aerobic exercise

  This project sees whether adding aerobic workouts to flywheel resistance training can reduce tiredness and boost strength in Veterans with stage 3–4 chronic kidney disease.

  NIH research U.s. Dept/vets Affairs Medical Center · Washington, United States · NIH-11220695

• rTMS plus aerobic exercise for post‑stroke depression and walking recovery

  This project combines repetitive transcranial magnetic stimulation (rTMS) with aerobic exercise to try to reduce depression and improve walking for people after a stroke.

  NIH research Medical University of South Carolina · Charleston, United States · NIH-11180064

• Combined aerobic cycling and brain-training using virtual reality to help prevent Alzheimer's

  This program combines virtual-reality cycling with cognitive games for older adults at risk for Alzheimer's to help keep thinking skills sharp.

  NIH research Moai Technologies, LLC · Maple Grove, United States · NIH-11177954

• Why aerobic exercise helps some older African American adults' brains more than others

  This project looks at whether genetic risk and fitness explain why aerobic exercise improves brain health and lowers Alzheimer's risk for some older African American adults but not others.

  NIH research Rutgers the State Univ of Nj Newark · Newark, United States · NIH-11176803

• Improving thinking and memory in breast cancer survivors with community aerobic exercise

  This project uses community-based aerobic exercise to help women 50+ who survived breast cancer improve thinking, memory, and brain health.

  NIH research Mayo Clinic Arizona · Scottsdale, United States · NIH-11136886

• Understanding why people with metabolic diseases struggle to adapt to aerobic exercise

  This study is looking into why people with metabolic diseases like diabetes might not get the full benefits from aerobic exercise, focusing on how high blood sugar levels can affect muscle responses, and it aims to find ways to help these individuals improve their exercise results for better health.

  NIH research Virginia Polytechnic Inst and St Univ · Blacksburg, United States · NIH-11133512

• Exercise Timing and Weight Loss

  This research explores if exercising in the morning versus the evening makes a difference in how much weight adults with overweight or obesity can lose.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11115583

• Aerobic exercise and muscle health to boost outcomes in colon cancer survivors

  A structured aerobic exercise program is tested to see if it improves muscle health and lowers cancer recurrence risk in people who have completed treatment for colon cancer.

  NIH research Adventhealth Orlando · Orlando, United States · NIH-11085079

• Using telehealth to improve thinking skills through exercise and cognitive training for people with schizophrenia.

  This study is looking at a new way to help people who have had their first episode of schizophrenia by using online exercise and brain training to boost their thinking skills and overall well-being.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11062469

• Using aerobic exercise to improve recovery after a stroke

  This study is looking at how doing aerobic exercise before rehabilitation activities, like playing a virtual reality game, can help stroke survivors recover better by improving their movement, thinking, and mood.

  NIH research Ralph H Johnson VA Medical Center · Charleston, United States · NIH-11056687

• How exercise affects brain health in older adults with a history of depression

  This study is looking at how aerobic exercise can help improve brain health and thinking skills in older adults who have dealt with late-life depression, with the hope of finding ways to boost their cognitive function without medication.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11056423

• Improving reading skills in stroke survivors with aphasia through exercise and targeted treatment

  This study is looking at how doing aerobic exercise along with a special reading program can help stroke survivors with aphasia improve their reading skills, making it easier for them to get back to their daily activities.

  NIH research Kessler Foundation, INC. · East Hanover, UNITED STATES · NIH-11046682

• How aerobic exercise affects fear learning in PTSD

  This study is looking at how different levels of aerobic exercise—light, moderate, or intense—can help people with PTSD feel less anxious and remember things better after therapy, and it also checks how a natural substance in the body might play a role in this process.

  NIH research University of Alabama in Tuscaloosa · Tuscaloosa, United States · NIH-11041172

• How genetics and aerobic exercise can slow down Parkinson's disease

  This study is looking at how doing high-energy aerobic exercise might help slow down Parkinson's disease and whether your genes play a role in this, and it's for people with Parkinson's who will join exercise programs in their communities.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11012304

• Using aerobic exercise to improve brain health in older adults with a history of depression

  This study is looking at how regular aerobic exercise can help improve brain health and thinking skills in older adults who have dealt with depression later in life, and it involves participants joining exercise programs while their brain activity and mental abilities are monitored.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-10986986

• Investigating fatigue in Veterans with chronic kidney disease through exercise

  This study is looking at how tiredness affects Veterans with chronic kidney disease and whether a special exercise program that mixes strength and aerobic workouts can help them feel less fatigued and improve their physical abilities.

  NIH research U.s. Dept/vets Affairs Medical Center · Washington, United States · NIH-10938014

• How exercise affects brain health and Alzheimer's risk in older African Americans

  This study is exploring how aerobic exercise, like cardio-dance, can boost brain health and lower the risk of Alzheimer's disease in older African Americans, while also looking at how genetics might affect how well exercise works for different people.

  NIH research Rutgers the State Univ of Nj Newark · Newark, United States · NIH-10909220

• Using exercise and brain stimulation to help people with depression after a stroke

  This study is looking at whether doing aerobic exercise along with a special treatment called rTMS can help people who are feeling depressed after a stroke feel better and recover more effectively.

  NIH research Medical University of South Carolina · Charleston, United States · NIH-10904283

• How the timing and nutrient status of aerobic exercise affects energy metabolism in adults with overweight and obesity

  This study is looking at how the time of day you exercise—morning or evening—and whether you've eaten before working out affects how your body burns energy, which could help people who are overweight or obese find better ways to lose weight and improve their health.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-10886945

• Understanding how hip muscle problems affect exercise in people with hip osteoarthritis

  This study is looking at how problems with hip muscles affect exercise for people with hip osteoarthritis, so we can help create better workout plans that make it easier for you to stay active and feel better.

  NIH research University of Kentucky · Lexington, United States · NIH-10873837

• Using aerobic exercise to enhance mobility in people with multiple sclerosis

  This study is looking at how aerobic exercise might help people with multiple sclerosis move better and repair their nerves, and it’s for anyone with MS who wants to see if exercise can make a positive difference in their condition.

  NIH research Oregon Health & Science University · Portland, United States · NIH-10864030

• Strength training for breathing muscles to lower blood pressure in postmenopausal women

  This study is looking at how a special breathing exercise can help lower blood pressure and improve blood vessel health in postmenopausal women, comparing it to regular aerobic exercise to see which might be easier to stick with and more beneficial for heart health.

  NIH research University of Colorado · Boulder, UNITED STATES · NIH-10786067

• Using MitoQ to improve exercise effects on blood vessel function in older women

  This study is looking at whether taking a daily supplement called MitoQ while doing moderate exercise can help improve blood vessel health in postmenopausal women, offering a potential alternative to hormone therapy for better heart health.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-10686453

• Improving brain function in breast cancer survivors through exercise

  This study is looking at how joining a community exercise program can help improve thinking and memory skills for women over 50 who have survived breast cancer, especially since they may experience some mental decline after treatment.

  NIH research Mayo Clinic Arizona · Scottsdale, United States · NIH-10625291

Related topics

Quick answers

How many Aerobic Exercise clinical trials are recruiting right now?

15, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in Turkey (Türkiye) (7 trials), United States (5 trials), France (1 trial), China (1 trial), Brazil (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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