Investigating heart health and exercise in people with HIV

Low Cardiorespiratory Fitness and Chronotropic Incompetence inHIV: Risk Factors, Cardiovascular Implications, and Exercise Training as Treatment

NIH-funded research University of California, San Francisco · NIH-11045688

This study is looking at how being less fit and having trouble increasing your heart rate can impact heart health for people living with HIV, and it will explore how exercise might help improve heart function and overall fitness.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-11045688 on NIH RePORTER

What this research studies

This research focuses on understanding how low cardiorespiratory fitness and chronotropic incompetence affect heart health in individuals living with HIV. The study aims to analyze the cardiovascular implications of these conditions and explore how exercise training can serve as a treatment option. Patients will be involved in hands-on research that combines clinical trials and advanced cardiac imaging to assess their fitness levels and heart function. The goal is to develop effective strategies to improve cardiovascular health among this population.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living with HIV who may be experiencing low cardiorespiratory fitness or related cardiovascular issues.

Not a fit: Patients who do not have HIV or those with advanced cardiovascular disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved cardiovascular health and exercise recommendations for patients with HIV.

How similar studies have performed: Previous research has shown promising results in improving cardiovascular health through exercise interventions in similar populations, indicating that this approach has potential.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virusadverse sequelae of coronavirus disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.