NIH-funded research R01 grant

Cognitive-behavioral therapy then exercise to lower type 2 diabetes risk in teenage girls

Official title: Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 Diabetes

Funded at Colorado State University · NIH-11324577 · Data updated 2026-11-12

Teen girls at risk for type 2 diabetes will try short-term talking therapy first, then structured exercise, to help lift mood, increase activity, and lower diabetes risk.

More Diabetes research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionColorado State University
NIH-funded
Lab location1 site (Fort Collins, United States)
Project startApril 1, 2022
Project endMarch 31, 2027
Funding year2026
Award (this year)$763,829
NIH project number5R01DK132557-05
Project IDNIH-11324577 on NIH RePORTER

Who could benefit from this research

Could help

Girls roughly ages 12–19 who are overweight or obese, at high risk for type 2 diabetes, and who have depressive symptoms are the ideal participants.

Less likely to help

Boys, adults, teens already diagnosed with type 2 diabetes, or teens without mood symptoms or who cannot take part in therapy or supervised exercise are unlikely to benefit from joining this project.

What this research studies

This project offers teen girls at high risk for type 2 diabetes a sequence of treatments: first short-term cognitive-behavioral therapy (CBT) to reduce depression, followed by a supervised exercise training program to improve fitness. Researchers will measure insulin resistance, physical activity, cardiorespiratory fitness, mood symptoms, and how well participants stick with the exercise plan before and after the interventions. The team focuses especially on females from historically disadvantaged racial and ethnic groups and will compare outcomes to see if treating mood first improves engagement with exercise and metabolic health. Sessions are likely delivered in person and include counseling and guided workouts with monitoring.

Why it matters

Potential benefit: If successful, this approach could lower insulin resistance and future diabetes risk while improving mood and exercise adherence in at-risk teen girls.

How similar studies have gone: Exercise alone has shown short-term metabolic benefits in adolescents but limited long-term effects, and using CBT first to boost exercise adherence is a newer approach with some supportive adult data but limited pediatric evidence.

Where this research is happening

  • Colorado State University
    Fort Collins, United States
    Active

Researchers

  • Principal investigator: Shomaker, Lauren Berger — Colorado State University
  • Study coordinator: Shomaker, Lauren Berger

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.