How gut bacteria affect exercise response in breast cancer survivors

Role of gut microbe composition in psychosocial symptom response to exercise training in breast cancer survivors

NIH-funded research University of Alabama at Birmingham · NIH-10844505

This study is looking at how the bacteria in your gut might affect how you feel during exercise if you're a breast cancer survivor dealing with fatigue, and it involves a 12-week workout program to see if getting active can help you feel better.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Alabama at Birmingham NIH-funded
Lab location1 site (Birmingham, United States)
Project IDNIH-10844505 on NIH RePORTER

What this research studies

This research investigates how the composition of gut microbiota influences the response to exercise training in breast cancer survivors, particularly those experiencing fatigue. The study will involve a randomized controlled trial where participants will engage in a 12-week aerobic exercise program. Assessments will be conducted at various intervals to evaluate changes in gut microbiota and fatigue levels. The goal is to understand the relationship between exercise, gut health, and symptom relief in this population.

Who could benefit from this research

Good fit: Ideal candidates for this research are breast cancer survivors who are experiencing fatigue and have low cardiorespiratory fitness.

Not a fit: Patients who are not breast cancer survivors or those who do not experience fatigue may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could help improve the quality of life for breast cancer survivors by reducing fatigue through tailored exercise interventions.

How similar studies have performed: While there has been limited research on this specific approach, previous studies have shown promising results linking exercise to improvements in gut microbiota and overall health.

Where this research is happening

Birmingham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions anti-cancer therapy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.