How gut bacteria affect exercise response in breast cancer survivors
Official title: Role of gut microbe composition in psychosocial symptom response to exercise training in breast cancer survivors
Funded at University of Alabama at Birmingham · NIH-10844505 · Data updated 2026-11-12
This study is looking at how the bacteria in your gut might affect how you feel during exercise if you're a breast cancer survivor dealing with fatigue, and it involves a 12-week workout program to see if getting active can help you feel better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project start | June 1, 2019 |
| Project end | November 30, 2025 |
| Funding year | 2025 |
| Award (this year) | $434,531 |
| NIH project number | 5R01CA235598-06 |
| Project ID | NIH-10844505 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are breast cancer survivors who are experiencing fatigue and have low cardiorespiratory fitness.
✕Less likely to help
Patients who are not breast cancer survivors or those who do not experience fatigue may not benefit from this research.
What this research studies
This research investigates how the composition of gut microbiota influences the response to exercise training in breast cancer survivors, particularly those experiencing fatigue. The study will involve a randomized controlled trial where participants will engage in a 12-week aerobic exercise program. Assessments will be conducted at various intervals to evaluate changes in gut microbiota and fatigue levels. The goal is to understand the relationship between exercise, gut health, and symptom relief in this population.
Why it matters
Potential benefit: If successful, this research could help improve the quality of life for breast cancer survivors by reducing fatigue through tailored exercise interventions.
How similar studies have gone: While there has been limited research on this specific approach, previous studies have shown promising results linking exercise to improvements in gut microbiota and overall health.
Where this research is happening
-
University of Alabama at Birmingham
Birmingham, United States Active
Researchers
- Principal investigator: Rogers, Laura Q — University of Alabama at Birmingham
- Study coordinator: Rogers, Laura Q
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.