Understanding how resistance training affects muscle growth and fitness
Towards Personalized Exercise: Identifying the Determinants of Individual Variation in Repeated Resistance Training (TraDeRe) and Examining Transferability of Responsiveness Between Resistance Training and Endurance Training
This study is testing how resistance training affects muscle growth and fitness in healthy people to see what factors might help them get better results.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | All |
| Sponsor | University of Jyvaskyla Academic / other |
| Locations | 1 site (Jyväskylä, Central Finland) |
| Trial ID | NCT06573086 on ClinicalTrials.gov |
What this trial studies
This research project aims to explore the reasons behind the varying responses individuals have to resistance training (RT) and how these responses may predict outcomes in endurance training (ET). By examining physiological, cellular, and molecular mechanisms, the study will investigate how different factors influence muscle growth and adaptation to exercise. A total of 362 healthy participants will undergo a 12-week RT program, with their responses monitored to identify predictors of training success and the impact of environmental factors such as nutrition and sleep.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy adults aged 18-50 who have previously participated in a related intervention.
Not a fit: Patients with metabolic, musculoskeletal, cardiovascular disorders, or those on medications affecting exercise performance may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to personalized exercise programs that optimize training outcomes for individuals based on their unique responses to resistance training.
How similar studies have performed: While there have been studies on resistance training responses, this multi-OMIC approach to understanding variability in responses is relatively novel and underexplored.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * age 18-50 * healthy (e.g., no diagnosed type 2 diabetes, cardiovascular disease, musculoskeletal disorders, etc.) * prior participation in intervention I (NCT05874986) Exclusion Criteria: * medication affecting the cardiovascular system or metabolism * metabolic, musculoskeletal, cardiovascular, or other diseases or disorders which may preclude the ability to perform exercise training and testing
Where this trial is running
Jyväskylä, Central Finland
- University of Jyväskylä — Jyväskylä, Central Finland, Finland (Recruiting)
Study contacts
- Principal investigator: Juha P Ahtiainen, Assoc.Prof. — University of Jyväskylä, Faculty of Sport and Health Sciences
- Study coordinator: Juha P Ahtiainen, Assoc.Prof.
- Email: juha.ahtiainen@jyu.fi
- Phone: +358408053740
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.