Condition

Cardiovascular Health clinical trials and research

• 14Clinical trials
• 184NIH research projects
• 5Countries

Newest Cardiovascular Health clinical trials

All recruiting trials (14)

• Digital Health Education to Improve Heart Health Across Different Socioeconomic Groups (e-DUCASS Advance)

  This study tests a 24-month digital health education program to see if it can improve cardiovascular health among people in Córdoba, Spain from varied socioeconomic backgrounds, by delivering weekly online content to families.

  Recruiting Maimónides Biomedical Research Institute of Córdoba · Córdoba · NCT07835386

• Omega-3 supplement to boost DHA and EPA levels in the blood

  This 12-week study tests whether the Omega Active supplement raises blood DHA and EPA levels in healthy adults aged 18–65 who have omega-3 needs.

  Recruiting Revive Active · Las Vegas, Nevada · NCT07753174

• Peanuts and stress: does eating peanuts affect heart health markers in people under high stress

  This study tests whether adding roasted peanuts to the diet can improve immune and cardiovascular risk markers in adults who report high chronic stress.

  Recruiting USDA, Western Human Nutrition Research Center · Davis, California · NCT07735221

• Beetroot Extract and Exercise for Health in Adults Aged 75+

  This study tests whether beetroot extract, alone and with a multicomponent exercise program, can improve blood pressure, functional performance, and cognitive function in adults 75 and older.

  Recruiting Fundacion Miguel Servet · Pamplona, Navarre · NCT07666685

• Dyadic Multidimensional Sleep Health Promotion for Couples

  A couples-focused program tests whether a multidimensional sleep health approach can improve sleep quality and blood pressure in both partners.

  Recruiting Columbia University · New York, New York · NCT07603245

• Self-affirmation and heart responses during grief

  This trial will test whether a brief self-affirmation exercise helps adults grieving a recent loss have calmer heart and blood pressure responses during and after recalling their loss.

  Recruiting University of South Florida · Tampa, Florida · NCT07356635

• A new insulin-sensitizing pill for adults with type 1 diabetes using closed‑loop insulin delivery

  This 12-week test will see if the oral drug CIR-0602K helps adults with type 1 diabetes who use closed-loop insulin systems spend more time in their target glucose range and use less insulin.

  Recruiting Phase 2 University of Virginia · Charlottesville, Virginia · NCT07186660

• Heart health program for home health aides

  This program tests whether a peer-coach–delivered version of the American Heart Association's Life's Essential 8 can help home health aides improve their heart health.

  Recruiting at 2 sites Weill Medical College of Cornell University · New York, New York and 1 other locations · NCT07067398

• Health Impact 360: Boosting physical, social, and mental health to prevent heart disease in communities

  A community program called Health Impact 360 is being tested to see if it improves heart health and well-being for adults in marginalized neighborhoods.

  Recruiting at 4 sites University of Michigan · Detroit, Michigan and 6 other locations · NCT07034352

• Judicious heart monitoring during HER2-targeted therapy for breast cancer

  This study tests a personalized heart-monitoring plan during HER2-positive breast cancer treatment to see if fewer, risk-tailored heart tests can safely replace routine quarterly imaging.

  Recruiting Women's College Hospital · Toronto, Ontario · NCT06930521

• Smartphone app to promote healthy lifestyles in firefighters

  This study tests whether a smartphone app can help firefighters in Taiwan live healthier lives and improve their mental and physical health compared to their usual care.

  Recruiting National Yang Ming Chiao Tung University · Taipei · NCT06862427

• Home visits to improve cardiovascular health for mothers and children

  This study is testing whether a special home visiting program can help improve heart health for mothers and their children in communities at risk for cardiovascular disease.

  Recruiting at 9 sites JHSPH Center for Clinical Trials · Birmingham, Alabama and 8 other locations · NCT06272045

• Home-based exercise program for kidney transplant recipients

  This study is testing whether a home-based exercise program can help kidney transplant recipients improve their fitness and overall health compared to different levels of exercise intensity.

  Recruiting at 2 sites KU Leuven · Ghent and 1 other locations · NCT06260579

• Evaluating how exercise affects body composition and fitness based on training status

  This study is testing how exercise affects body composition and fitness in people with different levels of training to see what differences there are.

  Recruiting Universidad Politecnica de Madrid · Madrid, Comunity of Madrid · NCT06246760

NIH-funded research (newest 40 of 184)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Enhancing Intergenerational Heart Health in Nigeria during Pregnancy and Early Life

  A research project will test a healthy eating and active living program for pregnant women with obesity in Nigeria to help improve heart health for the mother and her children.

  NIH research Washington University · Saint Louis, United States · NIH-11617678

• COVID-19 healthcare disruptions and heart health inequities in NYC adults with multiple conditions

  This project looks at how COVID-19-related gaps in care affected heart health in adults with several chronic conditions in New York City.

  NIH research New York University School of Medicine · New York, United States · NIH-11609174

• ENRICH: A Center to Support Healthy Hearts for Moms and Kids

  A nationwide effort at Johns Hopkins to test a consistent, family-focused program that helps mothers and their children develop healthier heart habits using home visiting, technology, and coordinated care.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11588691

• Early life air pollution and kids’ heart health: how metals in the air affect children from birth to age 12

  This grant studies how pollution from cooking fires and wood smoke in early life may shape a child’s heart health through age 12.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11554603

• Enhancing cardiovascular health for moms and kids at home

  A multi-center program tests whether enhanced home visiting can improve heart health and growth in families from economically challenged communities by collecting more accurate pediatric height/weight data.

  NIH research Washington University · Saint Louis, United States · NIH-11544412

• GLP-1 receptor drugs and heart-brain health in diabetes and Alzheimer’s risk

  A Duke-led study will explore how GLP-1 receptor medicines and exercise affect brain and heart health in models prone to diabetes and Alzheimer’s risk.

  NIH research Duke University · Durham, United States · NIH-11536555

• Cardiovascular health in the offspring of pregnancies affected by gestational glucose and weight

  This study follows young adults whose mothers had gestational diabetes or related conditions to understand how pregnancy health affects their heart and blood vessel health over time.

  NIH research Lurie Children's Hospital of Chicago · Chicago, United States · NIH-11529770

• Reducing artery inflammation in people with HIV using eplerenone and statins

  A multi-center trial will test whether adding the drug eplerenone to standard statin therapy reduces artery inflammation and lowers heart disease risk in people with HIV who already receive ART and statins.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11470337

• Glycemic and metabolic profiling during pregnancy to predict future heart disease risk

  A pregnancy-focused study uses blood tests and metabolic data to predict a mom’s risk of cardiovascular disease years after delivery.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11450457

• Gestational arsenic exposure and moms' heart health

  This grant studies how exposure to arsenic during pregnancy might affect a mother’s heart health, with findings that could help prevent serious pregnancy-related heart problems.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11448126

• Environmental toxins and kids’ heart health over time

  This project looks at how exposure to environmental pollutants may shape heart health from early childhood through young adulthood in families followed over years.

  NIH research Harvard Pilgrim Health Care, INC. · Canton, UNITED STATES · NIH-11447890

• Linking Sleep, Activity, and Genes to Heart Health

  This grant aims to understand how sleep and daily activity interact with our genes to affect heart health in a large, diverse group of people.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11426258

• Environmental toxins and their effects on ovarian and heart health

  Researchers will explore how youth exposure to the environmental toxin TCDD may harm ovarian function and later heart health in females.

  NIH research University of Cincinnati · Cincinnati, United States · NIH-11423959

• Reducing heart disease gaps for people with serious mental illness in community clinics

  A program at Johns Hopkins aims to help people with serious mental illness lower their risk of heart disease by adapting proven approaches for real-world community mental health settings.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11421434

• Rent Subsidies to Prevent Housing Instability and Protect Heart Health

  A funded plan will examine whether a short-term rent subsidy helps prevent housing instability and improves heart-related health outcomes for adults in Illinois.

  NIH research Northwestern University · Chicago, United States · NIH-11420455

• Adolescent Wealth and Heart Health: How family assets affect teens' cardiovascular risk

  This grant explores how family wealth, assets, and debts influence cardiovascular health in adolescents and young adults.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11420226

• Multiethnic look at DNA methylation and heart health over time

  A multiethnic study will follow adults to see how changes in DNA methylation relate to cardiovascular health and risk over several years.

  NIH research Tufts University Boston · Boston, United States · NIH-11417911

• Community Health Worker–Led Church-Based Plan to Improve Heart Health in African Americans

  A CHW-led, church-based program will help African American adults in Louisiana reduce heart disease risk by putting proven prevention steps into everyday life.

  NIH research Tulane University of Louisiana · New Orleans, United States · NIH-11415130

• Maternal heart health starts at home: Targeting social needs to improve pregnancy and postpartum heart health

  Aimed at improving heart health for pregnant and postpartum people by addressing social needs like housing and access to care.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11415084

• Pregnancy, lupus, and heart health in women with lupus

  This study looks at how managing lupus during pregnancy can affect blood pressure and heart health for women with the disease.

  NIH research Emory University · Atlanta, United States · NIH-11415013

• Enhancing Intergenerational Heart Health in Nigeria during Pregnancy and Early Life

  A study to test a family-focused program that promotes healthy eating and active living for pregnant women with obesity and their children in Nigeria to reduce future heart health problems.

  NIH research Washington University · Saint Louis, United States · NIH-11414880

• Virtual World Cardiac Rehab to Boost Heart Health for Cardiac Patients

  A nationwide study will test a 12-week virtual world-based cardiac rehab program against standard center-based rehab to see if it improves heart health and participation for adults with heart disease.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11414849

• Actionable multilevel strategies to boost heart health for people living with HIV

  A research project aims to create practical, community- and system-level ways to prevent heart disease in people with HIV.

  NIH research University of Florida · Gainesville, United States · NIH-11408151

• Beat-to-Beat: AI-powered help for rural heart health

  A new AI-enabled digital tool helps people in rural areas get accurate, local heart-health guidance through friendly video chats.

  NIH research Talk Story Health LLC · Honolulu, United States · NIH-11405675

• Impact of pregnancy microbiomes on mom and baby heart health in a diverse group

  Aimed at understanding how the microbiomes in the mother’s body relate to heart health risks for both mother and child during and after pregnancy, with a focus on diverse populations.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11404035

• Menopause, hot flashes, and heart health in midlife women

  This study looks at how menopause-related hot flashes may connect to heart disease risk in midlife women and whether treating hot flashes can improve heart health.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11403859

• Cardiovascular Health of Low-Income Working-Age Adults in the US

  This grant studies how low-income adults aged 18–64 experience heart and blood vessel health in the United States and how changes in health coverage affect their care.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11402609

• Understanding how teen stress affects a parent’s heart health

  A study following adolescents and their parents to see how daily stress in teens might influence heart-related risk in parents.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11402542

• Wildfires and Heart Health: How Smoke Affects Heart Disease and Ways to Help

  This grant looks at how wildfire smoke may worsen heart disease and tests ways to keep indoor air cleaner for adults with cardiovascular conditions.

  NIH research University of Montana · Missoula, United States · NIH-11401056

• Healthy Hearts: Better Heart Screening for Survivors via Online Support

  A new program tests if an online, nurse-guided heart-screening plan helps childhood cancer survivors stick with important heart tests.

  NIH research St. Jude Children's Research Hospital · Memphis, United States · NIH-11400309

• Early life air pollution and kids' heart health

  A study following children to see how exposure to household and outdoor air pollution from cooking fires and smoke affects heart health as they grow up.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11398571

• Disparities in heart health for young adults with type 1 diabetes

  A study to understand why heart disease risk differs among young people with type 1 diabetes, especially in Black and Hispanic communities.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11396445

• PANACHE: Cardiovascular Health in Asian American, Native Hawaiian, and Pacific Islander communities

  A large study will look at how cardiovascular diseases affect Asian American, Native Hawaiian, and Pacific Islander adults and what factors drive differences in risk and outcomes.

  NIH research Kaiser Foundation Research Institute · Oakland, UNITED STATES · NIH-11393356

• Early household cooking smoke and metals' effects on children's heart health

  This project looks at whether babies' and young children's exposure to cooking smoke and airborne metals affects their heart health up to age 12.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11392931

• Early-life household smoke and metal exposure and children's heart health

  This project looks at whether breathing cooking smoke and metals before and during infancy changes heart health up through age 12 for children born in Ghana.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11392928

• Understanding how hurricanes affect heart health over time

  This grant supports training a physician-scientist to improve programs that identify people at risk of heart problems after hurricanes, with the goal of protecting vulnerable adults.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-11392695

• ENRICH: Coordinating program to improve heart health for mothers and young children

  This program will support home visits plus mobile and telehealth tools to help mothers and children build heart-healthy habits and stay connected to care.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11388470

• 2-generation programs to boost cardiovascular health for moms and kids through home visiting

  A program in Indiana and Illinois uses home visiting services to help mothers and their children improve heart health.

  NIH research Northwestern University · Chicago, United States · NIH-11387791

• Allostatic Load and the DNA Methylome in Pregnancy and Heart Health

  This research looks at how chronic stress during and after pregnancy may shape DNA and heart health for mothers, with potential to improve understanding of cardiovascular risk after pregnancy.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11387740

• ENRICH: Coordinating Center to Promote Cardiovascular Health in Mothers and Children

  A nationwide effort to improve heart health in mothers and their young children by providing a centralized, coordinating hub that supports home visiting programs and uses tech tools to reach families where they already receive care.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11387702

Related topics

Quick answers

How many Cardiovascular Health clinical trials are recruiting right now?

14, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in United States (8 trials), Spain (3 trials), Belgium (1 trial), Taiwan (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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