Using MitoQ to improve exercise effects on blood vessel function in older women
Official title: MitoQ supplementation for restoring aerobic exercise training effects on endothelial function in postmenopausal women
Funded at University of Colorado Denver · NIH-10686453 · Data updated 2026-11-12
This study is looking at whether taking a daily supplement called MitoQ while doing moderate exercise can help improve blood vessel health in postmenopausal women, offering a potential alternative to hormone therapy for better heart health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | September 15, 2022 |
| Project end | August 31, 2025 |
| Funding year | 2022 |
| Award (this year) | $430,000 |
| NIH project number | 1R56AG072094-01A1 |
| Project ID | NIH-10686453 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are postmenopausal women experiencing cardiovascular health issues related to aging.
✕Less likely to help
Patients who are not postmenopausal or those who do not have cardiovascular concerns may not benefit from this research.
What this research studies
This research investigates how MitoQ, a mitochondrial-targeted antioxidant, can enhance the benefits of aerobic exercise on blood vessel function in postmenopausal women. The study will involve a 12-week program where participants will engage in moderate-intensity aerobic exercise while taking MitoQ daily. The goal is to determine if this combination can improve endothelial function, which is often impaired in older women due to lower estrogen levels. By focusing on this specific population, the research aims to find effective alternatives to estrogen therapy for cardiovascular health.
Why it matters
Potential benefit: If successful, this research could provide a new treatment option to improve cardiovascular health in postmenopausal women.
How similar studies have gone: Previous research has shown that antioxidants can improve endothelial function, suggesting potential success for this approach.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Moreau, Kerrie — University of Colorado Denver
- Study coordinator: Moreau, Kerrie
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.