NIH-funded research NIH-funded research

Finding protein markers that show how exercise helps heart failure patients

Official title: Identifying Proteomic Markers of Exercise Training in Heart Failure

Funded at Stanford University · NIH-11042809 · Data updated 2026-11-12

This study is looking at how exercise can help people with heart failure by checking for changes in certain proteins in their blood before and after they start an exercise program, so we can find better ways to help them feel better and recover.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionStanford University
NIH-funded
Lab location1 site (Stanford, United States)
Project startApril 1, 2023
Project endMarch 31, 2028
Funding year2025
Award (this year)$193,260
NIH project number5K23HL164980-03
Project IDNIH-11042809 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults aged 21 and older who have been diagnosed with heart failure.

Less likely to help

Patients with heart failure who are unable to participate in exercise training due to severe comorbidities may not benefit from this research.

What this research studies

This research investigates how exercise training can improve the health of patients with heart failure by identifying specific proteins in the blood that change with exercise. The study will use advanced proteomic profiling techniques to analyze blood samples from heart failure patients before and after they undergo exercise training. By comparing these results with healthy adults, the researchers aim to understand the molecular changes that occur in response to exercise, which could lead to better rehabilitation strategies for heart failure patients.

Why it matters

Potential benefit: If successful, this research could lead to improved exercise rehabilitation programs that enhance the quality of life for heart failure patients.

How similar studies have gone: Previous research has shown promising results in understanding the molecular effects of exercise in other populations, suggesting that this approach may yield valuable insights for heart failure patients as well.

Where this research is happening

  • Stanford University
    Stanford, United States
    Active

Researchers

  • Principal investigator: Katz, Daniel Hunter — Stanford University
  • Study coordinator: Katz, Daniel Hunter

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.