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Clinical trials and research at University of Michigan

• 165Clinical trials
• 9Countries

Newest trials

All recruiting trials (newest 150 of 165)

• Tributyrin for PSP: a virtual, early-phase study

  This study tests whether tributyrin is safe and tolerable in people with Progressive Supranuclear Palsy who are 45 or older, using virtual visits.

  Recruiting Phase 1/2 University of Michigan · Ann Arbor, Michigan · NCT07863180

• Powered vs Manual Toothbrushes for Kids: Does it affect Cavity Risk?

  This study tests whether using a powered toothbrush twice daily for a year lowers cavity risk in kids aged 8–12 compared with a standard manual brush, using fluoride toothpaste as the control.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07859553

• PIONEER-Prognosis: Using biomarkers and wearables to forecast recovery after mild traumatic brain injury

  This study tests whether blood biomarkers, health data from records, and wearables can help predict how people recover after a mild traumatic brain injury treated in the emergency department.

  Recruiting at 3 sites University of Michigan · Torrance, California and 4 other locations · NCT07858266

• Sex hormones, menopause, and exercise in aging women

  This study tests how hormonal status and resistance training affect age-related muscle and nerve function in postmenopausal women.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07848438

• RENEW: a digital program to help people with axial spondyloarthritis manage energy and symptoms

  A web-based, peer-led program called RENEW is tested to see if people with axial spondyloarthritis can easily use it, like it, and benefit from it in managing fatigue and symptoms.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07836374

• Biomarkers plus guidelines to reduce unnecessary brain CTs after head injury

  This trial tests whether adding GFAP and UCH-L1 biomarker results to standard guidelines can safely reduce head CT scans in adults with suspected traumatic brain injury who come to the emergency department.

  Recruiting at 6 sites University of Michigan · Sylmar, California and 5 other locations · NCT07829107

• Home-based hand rehab for people after stroke

  This pilot study tests a telerehabilitation hand program you do at home to see if it improves hand function for adults with chronic stroke compared with a standard home exercise plan.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07792655

• Morning bright light therapy for postpartum depression

  This study tests a wearable morning bright light device to see if it’s feasible and acceptable for people within six months after giving birth who have depressive symptoms.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07766161

• See if stopping antiseizure meds after being seizure‑free helps patients with epilepsy

  This study tests whether stopping antiseizure medications after a period of seizure freedom is safe and feasible for people with epilepsy.

  Recruiting Phase 4 University of Michigan · Ann Arbor, Michigan · NCT07750496

• Mobile health tools to boost activity in heart failure patients

  A mobile health program with push notifications, a digital coach, and a goal-setting app is being tested to see if it can help adults with heart failure be more physically active and stay active.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07750262

• Algorithm-informed care to find the best pain treatment for chronic low back pain

  This study tests whether an algorithm that uses a patient’s symptoms, history, and lifestyle can help pick the best treatment from physical therapy, duloxetine, acupressure, or PRISM-CBT for people with chronic low back pain.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07731750

• Getting diabetes support to see if it helps control blood sugar

  This study tests different social and financial support tools to help adults with diabetes manage their condition and improve their health.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07676188

• Modular powered knee braces to help move better and reduce knee pain

  A device with partial motor support is being tested in adults with knee OA to see if it can ease pain and reduce effort during daily activities.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07673328

• Noninvasive Thalamocortical Stimulation for Stuttering

  This study tests whether mild, focused ultrasound to a brain area involved in speech can safely improve fluency in adults who stutter.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07668882

• Bottle flow-rate test for babies and feeding patterns

  This study tests whether different bottle nipple flow rates affect how much milk a 4–6 month old infant drinks, how they feed, and their sleep, by watching 220 mother–infant pairs.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07665983

• AI helps detect proximal caries and guides treatment decisions

  AIM: See if using artificial intelligence to help detect proximal caries changes how dental students and junior clinicians decide on treatment.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07648212

• LRRK2-linked Parkinson’s: Brain Chemistry and Function in PD Patients

  This study tests how the LRRK2 gene mutation affects brain chemistry and function in people with Parkinson’s disease.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07642908

• Diet and counseling to see how meals affect gut health after CDI

  We’re testing whether different meal plans and health counseling can influence the gut microbiome and reduce chances of CDI coming back in adults who are being treated for CDI.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07613645

• Motivating Activity Through Text Messages to Increase Movement

  This trial tests whether different motivational text messages can help adults aged 40+ move more, by tracking steps and activity over 6 months.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07593677

• FETO with a Goldballoon device for fetuses with diaphragmatic hernia

  This study tests whether performing Fetoscopic Endoluminal Tracheal Occlusion on pregnancies with fetal diaphragmatic hernia improves baby survival and reduces long-term problems.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07577414

• Amitriptyline for IBS-like Symptoms in Quiescent Crohn's Disease

  This study tests whether low-dose amitriptyline can ease IBS-like abdominal pain and related symptoms in adults with Crohn's disease that is in remission.

  Recruiting Phase 2 University of Michigan · Ann Arbor, Michigan · NCT07556718

• Dynamic standing desk for people with Parkinson's

  This pilot will try a dynamic standing desk in people with Parkinson's to see if it improves walking compared with static standing or sitting.

  Recruiting Phase 1 University of Michigan · Ann Arbor, Michigan · NCT07543861

• Uninterrupted warfarin with a single vitamin K dose for surgery

  This study tries giving one dose of vitamin K before surgery to people on long-term warfarin to see if they can safely keep taking warfarin through the procedure.

  Recruiting Phase 4 University of Michigan · Ann Arbor, Michigan · NCT07515664

• Combining the Youth-Nominated Support Team with CBT for Black adolescents at acute suicide risk

  This project will test whether adding a computer-assisted Youth-Nominated Support Team to Cognitive Behavioral Therapy for Suicide Prevention helps Black adolescents (ages 12-17) who come to an urban emergency setting with suicidal thoughts or self-injury.

  Recruiting at 2 sites University of Michigan · Detroit, Michigan and 1 other locations · NCT07506460

• Aquamin for preventing pouch inflammation in UC patients with a J-pouch

  A Phase 2 study tests whether Aquamin®, a natural mineral supplement, can reduce inflammation and protect the gut lining in people with ulcerative colitis who have a J-pouch after ileal pouch-anal anastomosis.

  Recruiting Phase 2 University of Michigan · Ann Arbor, Michigan · NCT07501078

• Defining Objective Markers of Dietary Compliance in IBS

  This study tests whether a biomarker in stool or urine can reflect how much certain carbohydrates you eat, helping manage IBS.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07494968

• How metoprolol works in HFrEF patients with low versus high beta‑blocker genetic scores

  This trial will test if people with HFrEF who have a high beta‑blocker polygenic score respond differently to metoprolol than those with a low score.

  Recruiting Phase 4 University of Michigan · Ann Arbor, Michigan · NCT07490067

• Using lung cancer screening CT scans to find COPD (MAP2)

  This project will use lung cancer screening CT scans and spirometry in current and former smokers aged 50–80 with at least 20 pack-years to see if CT findings can identify people who have COPD.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07482475

• Michigan Weight Navigation Program (MiWeigh) to help adults with obesity lose weight

  This project tests whether adults with obesity and at least one related health condition lose more weight using the MiWeigh program than by receiving information about weight-loss strategies.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07465341

• Self-management program to improve health in inflammatory bowel disease

  A digital self-management program is being tested to see if it helps people with inflammatory bowel disease feel better and manage their symptoms alongside standard care.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07456566

• Cannabis use and IV sedation during wisdom tooth removal

  This project will see if people who use cannabis need different IV sedative doses or have different vital signs and breathing during wisdom tooth removal compared with people who don't use cannabis.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07423195

• Virtual-reality nature immersion for adults in outpatient alcohol treatment.

  This pilot will try immersive virtual-reality nature sessions to see if they help adults with alcohol use disorder and moderate-or-worse depression symptoms who are enrolled in an intensive outpatient program.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07413458

• Muscle relaxant versus vibrating pelvic massage wand plus pelvic floor therapy for high-tone pelvic floor dysfunction

  This trial will test whether taking a daily muscle relaxant (cyclobenzaprine) or using a vibrating pelvic floor massage wand, together with pelvic floor physical therapy, helps people with high-tone pelvic floor dysfunction reduce pain and improve function.

  Recruiting Phase 2/3 University of Michigan · Ann Arbor, Michigan · NCT07404397

• Diet approaches for gastrointestinal symptoms in systemic sclerosis

  This project will test whether three different diets reduce bloating and other gastrointestinal symptoms in people with systemic sclerosis.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07402226

• Virtual nature walks for depression in progressive multiple sclerosis

  This project tests whether immersive at-home virtual-reality nature walks using the Apple Vision Pro, added to usual care, can reduce depressive symptoms in people with progressive MS.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07392879

• Immediate versus delayed surgical reconstruction for bone defects around dental implants

  This trial will test whether doing bone grafting and membrane placement right away or waiting and doing it after initial healing works better for adults with peri-implantitis-related intra-bony defects around dental implants.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07325747

• PICTURE Pediatric: AI early-warning to spot kids likely to worsen

  This pilot tests an AI-based early warning system that gives real-time risk scores and alerts to care teams for pediatric patients on general wards and ED boarders to see if the workflow and interface achieve high compliance.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07304050

• Ureteral access sheath: omitting versus placing a stent after ureteroscopy

  We will test if leaving out a ureteral stent after ureteroscopy with an access sheath works as well as placing a stent for pre-stented adults with kidney or ureteral stones.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07297953

• AI Chatbot support for family caregivers of adults with TBI, dementia, or Huntington disease

  A mobile AI chatbot is tested to see if it’s easy to use and helpful for informal caregivers of adults with TBI, dementia, or Huntington disease.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07280650

• Using fingerprint-linked digital records and reminders to help children finish their malaria and routine vaccines

  This project will test whether a biometric-linked digital vaccination system plus voice-message reminders can help children in Ghana complete their malaria and routine vaccines.

  Recruiting University of Michigan · Oti Region · NCT07261280

• Upadacitinib plus steroids vs steroids alone for acute severe ulcerative colitis

  This will test whether adding upadacitinib (Rinvoq) to corticosteroids helps adults with acute severe ulcerative colitis, whether treated as inpatients or outpatients, recover faster than steroids alone.

  Recruiting Phase 4 University of Michigan · Ann Arbor, Michigan · NCT07258771

• Bringing safe, chlorinated water to communities in Kano, Nigeria

  This project will test whether community demonstrations and local chlorine redemption points increase household water chlorination among pregnant women and mothers of children under five in Kano State.

  Recruiting University of Michigan · Kano · NCT07246824

• STRATAFIX sutures for closing cranial and spine surgical wounds

  This project will test STRATAFIX sutures for closing cranial and spine surgical wounds in adults to learn about long-term safety and healing.

  Recruiting Phase 4 University of Michigan · Lansing, Michigan · NCT07225101

• Restoring consciousness with ultrasonic deep brain stimulation during anesthesia

  We will try low-intensity focused ultrasound during MRI in healthy adults sedated with propofol or dexmedetomidine to see if it speeds return of consciousness.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07221539

• Passive robots and electrical stimulation to help arm recovery after stroke

  This study tests whether combining a low-cost passive robotic device (SepaRRo) with noninvasive neuromuscular electrical stimulation (NeuRRoFES) can help stroke survivors improve upper‑limb movement during long-term, home‑friendly training.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07218276

• One IV dose of calcium gluconate given before cesarean to reduce bleeding in people at high risk for uterine atony

  This will try a single IV dose of calcium gluconate given around cesarean delivery to see if it reduces blood loss for pregnant people at high risk of uterine atony.

  Recruiting Phase 2 University of Michigan · Ann Arbor, Michigan · NCT07217899

• Personalized high-definition transcranial direct current stimulation for posterior cortical atrophy

  This trial will test whether personalized HD-tDCS can improve visual and thinking abilities in people with posterior cortical atrophy.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07191327

• Long-term use of a nasopharyngeal airway for obstructive sleep apnea

  This follow-up lets people who finished the parent trial keep using a nasopharyngeal airway to see how it works over the long term for obstructive sleep apnea.

  Recruiting at 2 sites University of Michigan · Ann Arbor, Michigan and 1 other locations · NCT07191314

• Motor brain circuits for speech production in adults who stutter

  We will use MRI while adults who stutter speak to test how motor brain areas and their connections work during continuous speech.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07180628

• Wearable neuromodulation to help bowel symptoms after spinal cord injury

  This study tests a wearable device that uses transcutaneous neuromodulation to see if it can lessen neurogenic bowel dysfunction in people with spinal cord injury, compared to a sham treatment.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07171489

• Tributyrin for memory, thinking, and walking problems in Parkinson's disease

  This trial will test whether taking tributyrin three times a day for about 80–100 days helps memory, thinking, walking, and balance in adults with Parkinson's disease or Parkinson disease dementia, and will monitor safety.

  Recruiting Phase 1/2 University of Michigan · Ann Arbor, Michigan · NCT07154511

• Estradiol-linked inflammation and nerve sensitization in endometriosis pelvic pain treated with relugolix

  This study will try relugolix combination therapy to see if it reduces pelvic pain, inflammation, and pain sensitivity in premenopausal women with moderate-to-severe endometriosis-related pelvic pain.

  Recruiting Phase 3 University of Michigan · Ann Arbor, Michigan · NCT07100782

• Brain and behavior patterns of sign-tracking versus goal-tracking in young adults

  We test whether differences in brain activity and behavior tied to 'sign-tracking' versus 'goal-tracking' help explain attention, impulse control, and reward responses in healthy 18–22-year-olds.

  Recruiting University of Michigan · Ann Arbor, Michigan and 1 other locations · NCT07094061

• Tirzepatide to improve blood sugar and triglycerides in partial lipodystrophy

  This trial will see if tirzepatide can help adults with familial partial lipodystrophy lower blood sugar and triglycerides by reducing how much they eat.

  Recruiting Phase 2 University of Michigan · Ann Arbor, Michigan · NCT07091734

• Improve implant site by adding a soft-tissue graft substitute over a bone graft

  We will test whether placing a soft-tissue graft substitute (acellular dermal matrix) over a bone graft at single implant sites helps improve the bone and gum health, appearance, and stability for adults with horizontal ridge deficiency.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07082244

• Health Impact 360: Boosting physical, social, and mental health to prevent heart disease in communities

  A community program called Health Impact 360 is being tested to see if it improves heart health and well-being for adults in marginalized neighborhoods.

  Recruiting at 4 sites University of Michigan · Detroit, Michigan and 6 other locations · NCT07034352

• How twice-weekly weight training affects blood vessel health in perimenopause

  This trial will test whether lifting weights twice a week for 16 weeks helps improve blood vessel health, mood, sleep, and menopause symptoms in women experiencing perimenopause.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07022340

• Sodium nitrate to prevent contrast-associated acute kidney injury

  This pilot will test whether taking sodium nitrate around the time of a coronary angiogram or contrast-enhanced CT can prevent contrast-associated acute kidney injury in people at high risk.

  Recruiting Phase 2 University of Michigan · Ann Arbor, Michigan · NCT07016074

• Measuring brain responses to small electrical stimulation in people with medication-resistant epilepsy

  We will test whether special electrodes and tiny electrical pulses can record brain responses in people with medication-resistant epilepsy who are having surgery to remove a seizure focus.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07014592

• Vorinostat to help prevent GVHD in young people with non-malignant conditions undergoing stem cell transplant

  This phase 2 study tests whether adding vorinostat to standard GVHD prevention can reduce GVHD after stem cell transplant in patients aged 1–26 with non-malignant disorders.

  Recruiting Phase 2 University of Michigan · Ann Arbor, Michigan · NCT06995521

• Using sacral nerve responses to guide sacral neuromodulation for overactive bladder

  This research will test whether choosing sacral nerve stimulation settings based on sacral evoked responses versus visual-motor responses helps adults with overactive bladder symptoms.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06983470

• Michigan telemedicine screening for glaucoma and other sight‑threatening eye problems

  This program tests whether a technology-enhanced telemedicine screening finds glaucoma, diabetic eye disease, and visually significant cataracts more often than a standard optometric exam for patients at a community health center.

  Recruiting University of Michigan · Flint, Michigan · NCT06934577

• Reducing unnecessary preoperative testing for low-risk surgeries

  This study is testing a new approach to see if we can cut down on unnecessary medical tests before low-risk surgeries to make things easier and better for patients.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06934564

• At-home dorsal genital nerve stimulation for female sexual dysfunction

  This pilot will test whether regular at-home dorsal genital nerve stimulation or use of a smart vibrator can help premenopausal and postmenopausal women with female sexual dysfunction improve arousal symptoms.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06932302

• ADAPT: HeartSteps program to increase activity after cardiac rehabilitation

  This 3-month test sees if the HeartSteps smartphone program plus a Fitbit can help people who are completing or recently finished phase II cardiac rehabilitation increase and keep up their physical activity.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06915220

• Online program to support families of LGBTQ youth

  This study is testing an online program to help families of LGBTQ youth understand and support their children better, especially those from diverse backgrounds.

  Recruiting Phase 2 University of Michigan · Ann Arbor, Michigan · NCT06839859

• Program to improve family routines and reduce childhood obesity in low-income families

  This study is testing two different programs to help low-income families create healthier routines around mealtime, sleep, and screen time to see if it can reduce childhood obesity.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06795490

• Using dapagliflozin to reduce cardiovascular risk after hypertensive pregnancies

  This study is testing if the medication dapagliflozin can help reduce heart risks for women who had high blood pressure during pregnancy after they give birth.

  Recruiting Phase 4 University of Michigan · Ann Arbor, Michigan · NCT06785116

• Women-only cardiac rehabilitation program

  This study tests whether a women-only cardiac rehabilitation program helps women aged 40-80 with heart issues do better than a standard program that includes both men and women.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06784895

• Delta-frequency alternating-current brain stimulation paired with choral reading for stuttering

  This project will try mild, noninvasive alternating-current brain stimulation (tACS) paired with choral reading to see if it reduces stuttering in English-speaking children and adults who currently stutter.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06740968

• Using therapy dogs to help reduce anxiety in children during dental procedures

  This study is testing if having therapy dogs present can help reduce anxiety in children aged 4 to 12 during dental procedures that involve local anesthesia.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06725134

• Internet-based therapy for older adults with mobility issues and depression

  This study tests if an online therapy program can help older adults with mobility issues feel less depressed and more socially connected.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06721559

• Store Safely: Firearm safety program for rural families

  This project will test a firearm safety program to help families with children who live in Michigan's Upper Peninsula store guns more safely.

  Recruiting University of Michigan · Ann Arbor, Michigan and 1 other locations · NCT06719713

• Using Varenicline to Reduce Falls in Parkinson's Disease

  This study is testing if the medication Varenicline can help people with Parkinson's disease and mild cognitive issues reduce their risk of falling and improve their ability to walk while doing other tasks.

  Recruiting Phase 2 University of Michigan · Ann Arbor, Michigan · NCT06679374

• NPA-OSA device tolerability, usability, and acclimation in adults with obstructive sleep apnea

  This pilot will test whether a small nasopharyngeal airway (NPA-OSA) device can reduce apneas and be tolerated by adults with moderate to severe obstructive sleep apnea who are not using CPAP.

  Recruiting at 2 sites University of Michigan · Ann Arbor, Michigan and 1 other locations · NCT06677151

• Comparing pain relief options for children after surgery

  This study tests which pain relief method works better for kids recovering from surgery: a mix of common pain relievers or a low dose of opioids with those pain relievers.

  Recruiting at 4 sites Phase 4 University of Michigan · Phoenix, Arizona and 8 other locations · NCT06671002

• Text-message support for parents after their teen's ER visit for suicide risk

  This program tests whether sending adaptive text messages to parents can help adolescents (ages 13–17) who come to the emergency room with recent suicidal thoughts or attempts.

  Recruiting at 2 sites University of Michigan · Ann Arbor, Michigan and 1 other locations · NCT06660199

• Combining vision rehabilitation with emotional therapy for patients with inherited retinal diseases

  This study is testing if combining vision rehabilitation with emotional therapy can help people with inherited retinal diseases feel better emotionally and improve their vision skills.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06651736

• Reducing unnecessary thyroid hormone use in older adults

  This study is testing a new program to help doctors give less unnecessary thyroid hormone to older adults by providing them with better information and support.

  Recruiting at 3 sites University of Michigan · San Francisco, California and 2 other locations · NCT06629272

• Training community members to be HealthyLifetime health coaches

  This trial will test whether community members trained as health coaches can do as well as nurse health coaches at delivering the HealthyLifetime virtual program to adults without complex chronic conditions.

  Recruiting University of Michigan · Ann Arbor, Michigan and 1 other locations · NCT06616246

• Improving coping to reduce suicide risk after ED discharge

  This study tests whether an electronic safety plan and supportive text messages can help adults who have recently had suicidal thoughts or behaviors after leaving the emergency department.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06614946

• Evaluation of a curriculum to prevent child sexual exploitation

  This study is testing a new program designed to teach high school students and school staff how to prevent child sexual exploitation and encourage them to help others in their community.

  Recruiting University of Michigan · Des Moines, Iowa · NCT06587529

• Internet-based cognitive behavioral therapy for depression in older adults

  This study is testing an online therapy program to see if it can help older adults who are stuck at home and feeling depressed feel better compared to regular care.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06584422

• Combining exercise coaching with insomnia treatment to reduce knee pain in older adults

  This study tests if adding sleep treatment to exercise coaching can help older adults with knee pain feel better than just exercise coaching alone.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06580561

• Testing light therapy and sleep changes for fibromyalgia symptoms

  This study is testing if using a special light in the morning and changing sleep habits can help people with fibromyalgia feel better.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06567886

• Neurofeedback-enhanced cognitive reappraisal training for young adults with anxiety

  This trial uses real-time fMRI neurofeedback to see if training the brain can help young adults with anxiety improve their emotion regulation and reappraisal skills.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06563310

• Using brain stimulation to improve hand movement control

  This study is testing whether a personalized brain stimulation technique can help healthy people improve their hand movement control better than a standard method.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06561165

• Split-belt treadmill training to improve knee biomechanics after ACL reconstruction

  This small pilot will test whether six weeks of split-belt treadmill training can change how your reconstructed knee is loaded when you walk.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06529692

• Using wearable devices to evaluate fall risk in older adults

  This study is testing a new smartphone app that uses wearable devices to help older adults check their risk of falling so they can take steps to stay safe.

  Recruiting University of Michigan · Flint, Michigan · NCT06508892

• Investigating brain stimulation effects on memory in older adults

  This study is testing if a type of brain stimulation can improve memory and brain function in older adults, especially those with mild cognitive impairment.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06453980

• Treatment for adrenal insufficiency in patients with Cushing syndrome using osilodrostat

  This study is testing if the medication osilodrostat, combined with a specific dose of another steroid, can help people with Cushing syndrome avoid adrenal insufficiency while keeping their hormone levels balanced.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06430528

• Bioresorbable airway splint for treating airway collapse in children

  This study is testing a new 3D-printed airway splint to see if it can help children with airway collapse breathe better without needing a tracheostomy tube.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06406452

• Comparing cryoablation and standard methods for pain control after thoracic surgery

  This study is testing if a new pain relief method called cryoablation works better than standard techniques for people recovering from thoracic surgery.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06384664

• Examining brain function and memory in relation to opioid use and childhood experiences

  This study is trying to see how tough childhood experiences affect brain function and memory in adults with opioid use disorder compared to healthy adults.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06355778

• Increasing dietary fiber in patients with heart failure and diabetes

  This study tests if adding potato starch to the diets of people with heart failure and diabetes can improve their gut health and overall well-being.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06337812

• Exploring links between food allergies and atopic dermatitis

  This study is trying to see if there are connections between food allergies and atopic dermatitis by looking at blood and skin samples from people with and without these conditions.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06300697

• Effects of SGLT2 inhibitors on kidney function in Type 2 diabetes

  This study is testing if the diabetes medication Canagliflozin can help protect kidney function in adults with Type 2 diabetes and early signs of kidney disease.

  Recruiting Phase 4 University of Michigan · Ann Arbor, Michigan · NCT06291155

• Coaching for Veterans to Use Cannabis for Chronic Pain Management

  This study is testing whether virtual coaching can help veterans with chronic pain use cannabis more effectively to manage their symptoms.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06283862

• Using a Regenerative Peripheral Nerve Interface to Improve Control of Lower Limb Prostheses

  This study is testing whether a new nerve interface can help people with above-knee amputations have better control and feeling in their robotic legs.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06275282

• Using cannabidiol to reduce opioid use after knee replacement surgery

  This study tests if taking cannabidiol (CBD) daily can help people use less opioid pain medication after knee replacement surgery.

  Recruiting Phase 2 University of Michigan · Ann Arbor, Michigan and 1 other locations · NCT06234631

• Using melatonin to improve mood and sleep in bipolar disorder

  This study is testing if a low dose of melatonin, along with a sleep program, can help improve mood and sleep for people with bipolar disorder.

  Recruiting Phase 2 University of Michigan · Ann Arbor, Michigan · NCT06226025

• Effects of CBD on chronic pain in veterans

  This study tests whether CBD can help veterans with chronic pain feel better compared to a placebo.

  Recruiting Phase 2 University of Michigan · Ann Arbor, Michigan · NCT06213233

• Online therapy for managing pain in fibromyalgia and lupus patients

  This study is testing an online therapy called Brief Pain Exposure Therapy to see if it can help adults with fibromyalgia and lupus manage their pain and improve their overall well-being.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06208514

• Using virtual reality to treat pain in hospitalized patients with inflammatory bowel disease

  This study tests if using virtual reality can help hospitalized patients with inflammatory bowel disease manage their pain better and feel more comfortable during their treatment.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06188793

• Adaptive control of powered prosthetic legs for amputees

  This study is testing a new way to make powered prosthetic legs work better for amputees by adapting to different walking speeds and activities.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06138977

• Community-based treatment for glaucoma

  This study tests if community support and education can encourage Black or African American people who have been screened for glaucoma to seek eye care and prevent blindness.

  Recruiting University of Michigan · Ann Arbor, Michigan and 1 other locations · NCT06124521

• Identifying biomarkers for healing diabetic foot ulcers

  This study is trying to find specific markers in the body that can help predict which diabetic foot ulcers are likely to heal, so doctors can better manage treatment for patients with these wounds.

  Recruiting at 8 sites University of Michigan · Tucson, Arizona and 8 other locations · NCT06104969

• Clinician satisfaction with the VERABAND wearable activity monitor

  This study will test whether giving wearable VERABAND activity monitors to people with chronic low back pain helps clinicians find the device usable and likely to use in patient care.

  Recruiting at 2 sites University of Michigan · La Jolla, California and 2 other locations · NCT06080464

• Investigating the effects of reducing ultra-processed food intake on food addiction

  This study tests if reducing ultra-processed foods can help people with food addiction feel better and stick to a healthier diet.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06044285

• Understanding how metabolism and inflammation affect diabetes in teens

  This study is trying to see how body weight, lifestyle, and diet affect inflammation and metabolism in teens to better understand diabetes risk.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06007404

• Anthocyanin-rich grape powder to prevent post-operative atrial fibrillation

  We will test whether taking freeze-dried, anthocyanin-rich table grape powder before and after elective mitral valve surgery can reduce the chance of developing atrial fibrillation in adults aged 50–79 who are in normal sinus rhythm.

  Recruiting Phase 1/2 University of Michigan · Ann Arbor, Michigan · NCT05991700

• Using silver diamine fluoride to improve anesthesia in children with hypomineralized molars

  This study is testing if applying silver diamine fluoride before dental work can help make local anesthesia work better and reduce pain for children with sensitive molars.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT05964387

• Using a special breathing tube to improve intubation accuracy

  This study is testing a new type of breathing tube to see if it helps doctors place the tube more accurately during heart procedures.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT05941013

• Comparing two approaches to prevent delirium in hospitalized older adults

  This study tests whether involving family members in care can help prevent delirium in older adults during hospital stays better than the standard Hospital Elder Life Program alone.

  Recruiting at 7 sites University of Michigan · Orange, California and 6 other locations · NCT05929703

• Program to prevent youth gun violence in Washington D.C.

  This study is testing a summer job program in Washington D.C. to see if it helps young people change their behavior and attitudes about gun violence.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT05887973

• Personalized treatment for acute severe ulcerative colitis

  This study is testing different personalized treatment options for people in the hospital with severe ulcerative colitis to see which ones work best and are safe.

  Recruiting Phase 4 University of Michigan · Ann Arbor, Michigan · NCT05867329

• Comparing stent placement versus omission after kidney stone treatment

  This study is testing whether putting in a stent after kidney stone treatment helps patients feel better and need fewer extra doctor visits compared to not using a stent at all.

  Recruiting at 16 sites University of Michigan · Tucson, Arizona and 15 other locations · NCT05866081

• Examining a low sulfur diet for treating persistent symptoms in Crohn's disease

  This study tests if a low sulfur diet can help people with Crohn's disease who still have symptoms feel better after 8 weeks.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT05849012

• Digital intervention for managing chronic lower back pain

  This study is testing if a personalized online program can help people with chronic lower back pain manage their pain better.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT05843890

• Improving sleep in adults with cannabis use issues

  This study is testing whether a special online therapy for sleep problems can help adults who use cannabis for sleep feel better and sleep more soundly compared to regular sleep education.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT05814822

• Effects of weight loss with and without exercise on metabolic health

  This study is testing whether losing weight with exercise helps improve metabolic health more than just losing weight through dieting alone for people with obesity.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT05806801

• Non-invasive brain stimulation for chronic migraine relief

  This study is testing whether a type of brain stimulation can help people with chronic migraines feel better compared to a fake treatment.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT05769348

• Reducing PTSD symptoms in first responders and healthcare workers

  This study tests if a new talk therapy for PTSD can help first responders and healthcare workers feel better than the usual support they get.

  Recruiting at 10 sites University of Michigan · San Diego, California and 13 other locations · NCT05751473

• Comparing pain relief methods after surgery

  This study is testing whether a combination of over-the-counter pain relievers works better and has fewer side effects than low-dose opioids for people recovering from common surgeries.

  Recruiting at 8 sites Phase 4 University of Michigan · Ann Arbor, Michigan and 7 other locations · NCT05722002

• Impact of meetings between ICU patients and their doctors on burnout

  This study tests if having meetings between ICU patients and their doctors can help reduce burnout and improve job satisfaction for the doctors.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT05713669

• Community partnerships to address the opioid crisis

  This study is testing a new online program that helps people recovering from opioid use disorder fix small legal issues that might be holding them back.

  Recruiting at 2 sites University of Michigan · Ann Arbor, Michigan and 1 other locations · NCT05665179

• Observational study on kidney transplant recurrence in FSGS and MCD

  This study is looking at patients with kidney diseases called FSGS and MCD who have had or will have a kidney transplant to see how often these diseases come back afterward.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT05650619

• Using a special airway device to treat sleep apnea in children with weak muscles

  This study is testing a special airway device to see if it can help children with weak muscles who have sleep apnea breathe better at night without needing surgery.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT05527652

• Home treatment for abdominal pain in IBS with constipation

  This study is testing if a new electrical treatment and a common medication can help people with irritable bowel syndrome and constipation feel less abdominal pain.

  Recruiting Phase 2/3 University of Michigan · Ann Arbor, Michigan · NCT05519683

• Exploring experiences of patients and parents dealing with swelling from Nephrotic Syndrome

  This study talks to patients and parents about their experiences with swelling from Nephrotic Syndrome to help create better ways to measure how new treatments work.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT05505500

• Identifying biomarkers for stress vulnerability and resilience in students

  This study is testing how a mobile app that teaches stress management skills can help new college students understand their stress levels and build resilience against stress.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT05498207

• Improving PTSD treatment outcomes using adaptive therapy approaches

  This study tests if using a flexible approach to therapy for PTSD, starting with simpler treatments and adjusting based on how patients respond, can lead to better results.

  Recruiting at 12 sites University of Michigan · Baldwin, Michigan and 12 other locations · NCT05457985

• Mobile health intervention for asthma management in young African American adults

  This study is testing a mobile health program to help young African American adults with asthma manage their condition better and improve their quality of life.

  Recruiting University of Michigan · Tallahassee, Florida and 2 other locations · NCT05445583

• Effect of cooling duration on recovery in children after cardiac arrest

  This study is testing if cooling children who are in a coma after a cardiac arrest for longer periods can help them recover better.

  Recruiting at 62 sites University of Michigan · Birmingham, Alabama and 64 other locations · NCT05376267

• Comparing two anesthetics for sleep endoscopy in children with sleep apnea

  This study is testing which of two anesthetics works better during sleep endoscopy for kids with sleep apnea to see how it affects their airway and future treatment outcomes.

  Recruiting Phase 2 University of Michigan · Ann Arbor, Michigan · NCT05303987

• Comparing rhythm perception in children who stutter and those who don't

  This study tests how children who stutter perceive and produce rhythm compared to those who don’t, using fun tasks and brain scans to learn more about stuttering.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT05286151

• Effects of Cannabidiol and Tetrahydrocannabinol on Sleep and Pain in Multiple Sclerosis

  This study is testing whether CBD and THC can help people with multiple sclerosis sleep better and reduce their pain.

  Recruiting Phase 2 University of Michigan · Ann Arbor, Michigan · NCT05269628

• Exploring how dupilumab works differently in various ethnic groups with atopic dermatitis

  This study is testing how well dupilumab works for people with atopic dermatitis from different ethnic backgrounds, like Caucasian, Asian, and African American, to see if their responses vary.

  Recruiting Phase 4 University of Michigan · Ann Arbor, Michigan · NCT05268107

• Modular powered orthoses to enhance movement in patients

  This study is testing new powered leg braces to see if they can help people with weak joints move better and improve their everyday activities.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT05240014

• Aquamin® for reducing bad breath in adults

  This study tests whether Aquamin®, a multi-mineral product from red marine algae, can reduce halitosis after 90 days in adults who report bad breath.

  Recruiting Phase 2 University of Michigan · Ann Arbor, Michigan · NCT05058638

• Grocery delivery to support healthy weight gain in low-income pregnant young women

  This study is testing if grocery delivery of healthy foods can help low-income pregnant young women in Michigan gain weight safely and improve their diets.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT05000645

• Effects of cannabinoids on knee osteoarthritis pain

  This study is testing if daily treatment with THC, CBD, or both can help people with knee osteoarthritis feel less pain and improve their symptoms.

  Recruiting Phase 2 University of Michigan · Ann Arbor, Michigan · NCT04992624

• Monitoring biomarkers in traumatic brain injury treatment

  This study is trying to see if tracking certain biological markers can help doctors find the best treatments for people with severe traumatic brain injuries.

  Recruiting at 6 sites University of Michigan · San Diego, California and 10 other locations · NCT04855396

• Genetic study of rotator cuff tears

  This study is testing whether certain genes can increase the risk of rotator cuff tears in people by comparing those with tears to those without.

  Recruiting at 3 sites University of Michigan · Iowa City, Iowa and 9 other locations · NCT04831164

• Effects of exercise on fat tissue in obese individuals

  This study tests how exercise affects fat tissue in people with obesity to see if it can help improve their metabolism and manage weight better.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT04812314

• NEPTUNE Match: Personalized matching of patients to kidney treatment options

  This project will try a system that matches people in the NEPTUNE cohort who have nephrotic syndromes or related kidney diseases with suitable clinical trials and shares those matches with patients and their doctors.

  Recruiting at 15 sites University of Michigan · Atlanta, Georgia and 15 other locations · NCT04571658

• Using Deferoxamine to treat Aneurysmal Subarachnoid Hemorrhage

  This study is testing if a drug called deferoxamine can help people with aneurysmal subarachnoid hemorrhage recover better by reducing complications from iron release.

  Recruiting Phase 2 University of Michigan · Ann Arbor, Michigan · NCT04566991

• Imaging cholesterol trafficking in the adrenal gland using a new radiotracer

  This study is testing a new imaging tool to see if it can help get clearer pictures of the adrenal gland in both healthy people and those with adrenal problems.

  Recruiting Early Phase 1 University of Michigan · Ann Arbor, Michigan and 1 other locations · NCT04546126

• Imaging cholesterol trafficking in healthy individuals using a new PET tracer

  This study is testing a new imaging method to see how cholesterol moves in the body by using a special tracer in healthy people.

  Recruiting Early Phase 1 University of Michigan · Ann Arbor, Michigan · NCT04532489

• Understanding Fatigability in People with Diabetes

  This study is testing how different exercise methods can help people with pre-diabetes and type 2 diabetes feel less tired during workouts and improve their overall muscle health.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT04442451

Showing recruiting studies first, then the newest. Describe your situation to find the ones that fit you.

Quick answers

How many clinical trials run by University of Michigan are recruiting right now?

165, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United States (163 trials), Canada (4 trials), Australia (1 trial), New Zealand (1 trial), United Kingdom (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 16, Phase 4: 11, Phase 1/2: 3, Early Phase 1: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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