Comparing cryoablation and standard methods for pain control after thoracic surgery
Official title: Cryoablation Effects on Acute and Chronic Pain After Thoracotomy and Thoracoscopy
Run by University of Michigan · NCT06384664 · Data updated 2026-11-12
This study is testing if a new pain relief method called cryoablation works better than standard techniques for people recovering from thoracic surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | University of Michigan Academic / other |
| Locations | 1 site (Ann Arbor, Michigan) |
| Status | Recruiting |
| Started | June 3, 2024 |
| Main results expected | April 2027 |
| Study ends | April 2028 |
| Registry record updated | August 28, 2025 |
| Trial ID | NCT06384664 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are opioid-naïve patients scheduled for elective open thoracic or minimally invasive procedures at Michigan Medicine.
✕Probably not a fit
Patients with prior thoracic surgery, cognitive impairments, or psychological disorders may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the effectiveness of cryoablation for managing postoperative pain in patients undergoing thoracotomy or thoracoscopy. Researchers will compare this newer method to traditional pain control techniques, such as epidural and intercostal nerve blocks. The goal is to determine whether cryoablation offers superior pain relief for patients recovering from these intrathoracic procedures. The study will involve patients who are opioid naïve and meet specific eligibility criteria.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing thoracic surgery.
How similar studies have gone: While the use of cryoablation for pain management is a newer approach, similar studies have shown promising results in other surgical contexts.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who could receive cryoablation in an elective open thoracic (posterolateral thoracotomy) or minimally invasive (thoracoscopy, including robotic) procedures at Michigan Medicine * Patient is opioid naïve Exclusion Criteria: * Patients who are pregnant * Patients with cognitive impairment * Patients with psychological disorders * Patients with prior thoracic surgery * Patients with fibromyalgia * Patients with redo ipsilateral thoracic surgery * Patients undergoing bilateral thoracotomy
Where it's running
-
University of Michigan
Ann Arbor, Michigan, United States Recruiting
Study contacts
- Principal investigator: Rishindra Reddy, MD, MBA — University of Michigan
- Study coordinator: Shari L Barnett
- Email: shbailey@umich.edu
- Phone: 734-936-4561
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.