Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Comparing cryoablation and standard methods for pain control after thoracic surgery

Official title: Cryoablation Effects on Acute and Chronic Pain After Thoracotomy and Thoracoscopy

Run by University of Michigan · NCT06384664 · Data updated 2026-11-12

This study is testing if a new pain relief method called cryoablation works better than standard techniques for people recovering from thoracic surgery.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment80 (estimated)
SponsorUniversity of Michigan
Academic / other
Locations1 site (Ann Arbor, Michigan)
StatusRecruiting
StartedJune 3, 2024
Main results expectedApril 2027
Study endsApril 2028
Registry record updatedAugust 28, 2025
Trial IDNCT06384664 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are opioid-naïve patients scheduled for elective open thoracic or minimally invasive procedures at Michigan Medicine.

Probably not a fit

Patients with prior thoracic surgery, cognitive impairments, or psychological disorders may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of cryoablation for managing postoperative pain in patients undergoing thoracotomy or thoracoscopy. Researchers will compare this newer method to traditional pain control techniques, such as epidural and intercostal nerve blocks. The goal is to determine whether cryoablation offers superior pain relief for patients recovering from these intrathoracic procedures. The study will involve patients who are opioid naïve and meet specific eligibility criteria.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing thoracic surgery.

How similar studies have gone: While the use of cryoablation for pain management is a newer approach, similar studies have shown promising results in other surgical contexts.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients who could receive cryoablation in an elective open thoracic (posterolateral thoracotomy) or minimally invasive (thoracoscopy, including robotic) procedures at Michigan Medicine
* Patient is opioid naïve

Exclusion Criteria:

* Patients who are pregnant
* Patients with cognitive impairment
* Patients with psychological disorders
* Patients with prior thoracic surgery
* Patients with fibromyalgia
* Patients with redo ipsilateral thoracic surgery
* Patients undergoing bilateral thoracotomy

Where it's running

  • University of Michigan
    Ann Arbor, Michigan, United States
    Recruiting

Study contacts

  • Principal investigator: Rishindra Reddy, MD, MBA — University of Michigan
  • Study coordinator: Shari L Barnett
  • Email: shbailey@umich.edu
  • Phone: 734-936-4561

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.