Reducing PTSD symptoms in first responders and healthcare workers

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of a brief talk therapy treatment called Prolonged Exposure for Primary Care (PE-PC) in reducing PTSD symptoms among first responders and frontline healthcare workers. Participants will receive this treatment through Employee Assistance Programs (EAPs) and will be compared to those receiving standard EAP treatment. The central hypothesis is that PE-PC will lead to greater reductions in PTSD symptoms and improved functioning compared to usual care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Are employees at an orginization served by a participating EAP
* Have a Post-Traumatic Stress Disorder Checklist for Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (PCL-5) score ≥33
* Have had psychotropic medication stability for at least 4 weeks

Inclusion criteria for the qualitative portion of the study:

\- Enrolled into the randomized clinical trial and were a treatment responder or were a treatment non-responder

Exclusion Criteria:

* Severe cognitive impairment that in the judgment of the investigators makes it unlikely that the participant can adhere to the study regimen (as evidenced by confusion, inability to track discussion or answer questions, or other clear and significant indicators of cognitive impairment)
* High risk of suicide (defined as meeting criteria for Action Step 3 on the Participant Suicide Risk Screening form: found in protocol)
* Need for detoxification
* Active psychosis or unmanaged bipolar disorder, as measured by items 12 and 13 of the cross cutting assessment
* Currently engagement in a trauma-focused behavioral treatment (such as Prolonged Exposure or Cognitive Processing Therapy).
* Patients who do not speak English will be excluded for logistical reasons.

Where it's running

• Tanner Health System
  Carrollton, Georgia, United States Recruiting
• University of Michigan
  Ann Arbor, Michigan, United States Recruiting
• Detroit Fire Department
  Detroit, Michigan, United States Recruiting
• Health Management Systems of America
  Detroit, Michigan, United States Recruiting
• Michigan State University
  East Lansing, Michigan, United States Recruiting
• Rutgers Health
  Piscataway, New Jersey, United States Recruiting

Study contacts

• Principal investigator: Rebecca Sripada, PhD — University of Michigan
• Study coordinator: James Garlick
• Email: jgarlick@med.umich.edu
• Phone: 734-232-2663

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.