RENEW: a digital program to help people with axial spondyloarthritis manage energy and symptoms

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study tests a web-based, peer-led program (RENEW) for adults with axial spondyloarthritis. It focuses on usability, user satisfaction, and impact on symptom burden and energy levels. Participants engage in virtual coaching and complete online assessments to track changes over time. The study emphasizes feasibility and acceptability before broader efficacy testing.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Physician-diagnosed axSpA (including non-radiographic axSpA)
* Have moderate to severe fatigue (average of ≥4/7 on the Fatigue Severity Scale)
* Access to a computer, tablet, or smartphone with internet connection
* Ability to speak and read English
* Willingness to participate in virtual Zoom coaching sessions and complete online assessments
* Interested in making some changes and trying new ways to improve health and well-being

Exclusion Criteria:

* Currently enrolled in other clinical trials
* Currently undergoing structured rehabilitation or psychological treatment for major depressive disorder
* Significant cognitive impairment that would prevent informed consent or participation
* Severe psychiatric illness that would contraindicate participation

Where it's running

• University of Michigan
  Ann Arbor, Michigan, United States Recruiting

Study contacts

• Principal investigator: Susan Murphy, ScD, OTR — University of Michigan
• Study coordinator: Elizabeth Haro
• Email: elharo@umich.edu
• Phone: 734-998-7124

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Surface topography and spine damage in radiographic axial spondyloarthritis

  This study tests whether a radiation-free 3D surface topography method can reflect spine damage and sagittal balance in adults with radiographic axial spondyloarthritis.

  Recruiting Ankara Etlik City Hospital · Ankara, Yenimahalle · NCT07855393

• ExerciseRx app for people with axial spondyloarthritis

  A mobile app called ExerciseRx is tested to see if it helps people with axial spondyloarthritis exercise more regularly and feel better than usual care.

  Recruiting at 2 sites University of Washington · Seattle, Washington and 1 other locations · NCT07642622

• Carotid ultrasound to guide prevention of heart disease in inflammatory rheumatic diseases

  In people with inflammatory rheumatic diseases like RA, PsA, AxSpA, or SLE who are at modest cardiovascular risk, a carotid ultrasound test is used to see if they should start stronger lipid-lowering therapy to prevent heart problems.

  Recruiting at 7 sites Phase 4 Instituto de Investigación Marqués de Valdecilla · Alicante, Alicante and 16 other locations · NCT07611747

• Bimekizumab by IV infusion versus subcutaneous injection for adults with psoriatic arthritis or axial spondyloarthritis

  This trial tests whether bimekizumab given by intravenous (IV) infusion behaves the same in the body as the usual subcutaneous injection in adults with psoriatic arthritis or axial spondyloarthritis.

  Recruiting at 65 sites Phase 1 UCB Pharma · Peoria, Arizona and 64 other locations · NCT07290036

• Butantan live tetravalent dengue vaccine for people with autoimmune rheumatic diseases

  This study will test whether a single dose of the Butantan live tetravalent dengue vaccine is safe and produces immune responses in clinically stable people aged 12–59 with autoimmune rheumatic diseases compared with matched healthy volunteers.

  Recruiting at 2 sites Phase 4 University of Sao Paulo General Hospital · São Paulo, São Paulo and 1 other locations · NCT07087912

• Assessing Bimekizumab Levels in Breast Milk of Nursing Mothers

  This study tests how much of the medication bimekizumab is found in the breast milk of mothers who have been using it for at least 12 weeks after giving birth to see if it's safe for their babies.

  Recruiting at 14 sites Phase 1 UCB Pharma · Santa Monica, California and 13 other locations · NCT06888193

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.