Measuring brain responses to small electrical stimulation in people with medication-resistant epilepsy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-site project at the University of Michigan uses a novel combination of recording electrodes and stimulating probes placed on or in the brain during clinically indicated epilepsy surgery. Investigators will deliver small electrical pulses and record evoked cortical responses from the implanted electrodes. The work aims to characterize how the cortex responds to these signals to improve localization of seizure-related areas. Participants with permanent electronic implants or medical conditions that prevent safe electrode placement will be excluded.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with medication intractable epilepsy who are recommended to undergo brain surgery to remove a "seizure" focus
* Can provide informed consent for the study and willing to participate

Exclusion Criteria:

* Presence of a permanent electronic implant
* Any chronic medical conditions that prevent safe placement of electrodes

Where it's running

• University of Michigan
  Ann Arbor, Michigan, United States Recruiting

Study contacts

• Principal investigator: Matthew Willsey, MD, PhD — University of Michigan
• Study coordinator: Ron Ball
• Email: rmball@umich.edu
• Phone: 734 936-7010

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.