Sponsor or institution

Clinical trials and research at Shanghai Zhongshan Hospital

• 111Clinical trials
• 2New in 30 days
• 3Countries

Newest trials

All recruiting trials (111)

• Abnormal menstrual bleeding in women on antithrombotic drugs after heart surgery

  This study looks at whether women on blood thinners after heart surgery have abnormal menstrual bleeding and what factors might put some at higher risk.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07870941

• Sleep and circadian care for ICU patients

  This study tests a multicomponent sleep and circadian rhythm program in adult ICU patients to see if it helps keep daily rhythms and sleep better.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07869901

• Thymalfasin added to standard care for adults with sepsis and immune dysfunction

  This study tests whether thymosin alpha-1 helps restore immune function in adults with sepsis who have weakened immunity.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07866118

• Multicenter group study of sepsis and ARDS in China

  This study tests how sepsis and ARDS differ among adults across several Chinese hospitals and builds a biobank to understand why some patients do better or worse.

  Recruiting at 24 sites Shanghai Zhongshan Hospital · Xiamen, Fujian and 23 other locations · NCT07863908

• Adaptive intraoperative biopsy system for prostate cancer using imaging and metabolic feedback

  Aiming to test a smart biopsy approach that combines preoperative imaging with real-time metabolic signals to guide where to take prostate biopsy cores for better precision in men suspected of prostate cancer.

  Recruiting at 4 sites Shanghai Zhongshan Hospital · Shanghai and 3 other locations · NCT07856017

• Aortic and Vascular Graft Infection Study: A Look at Causes and Outcomes

  This study follows adults with suspected or confirmed infections of the aorta or vascular grafts to see what causes the infections and how they respond to treatment using blood tests, tissue samples, and imaging.

  Recruiting Shanghai Zhongshan Hospital · Shanghai · NCT07847346

• Trends and risk factors for adverse events after primary PCI in AMI patients over 20 years

  This study looks at real-world AMI patients who had a primary PCI to see how often serious events happen during a 2-year follow-up and what factors predict them.

  Recruiting Shanghai Zhongshan Hospital · Shanghai · NCT07833995

• TEE-Guided vs CCTA-Guided Preprocedural Imaging for Left Atrial Appendage Closure

  This trial tests whether using transesophageal echocardiography (TEE) or cardiac CT angiography (CCTA) for preprocedural planning helps people with nonvalvular atrial fibrillation who are getting a left atrial appendage closure determine the best device size and approach.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07815119

• Quadruple Therapy for Type 2 Diabetic Kidney Disease

  This study tests whether adding a fourth medication to standard therapy helps people with type 2 diabetic kidney disease see a bigger drop in urine protein compared with three other treatment combinations.

  Recruiting Phase 4 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07775846

• Blood biomarkers to predict response to atezolizumab plus bevacizumab in hepatocellular carcinoma

  This study tests whether blood-based biomarkers can predict which patients with advanced liver cancer will respond to first-line atezolizumab plus bevacizumab.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07734857

• First-line QL1706 plus Gemcitabine and Cisplatin for PD-L1–positive biliary tract cancer

  This study tests whether adding QL1706 to standard gemcitabine and cisplatin can help shrink tumors in adults with PD-L1–positive biliary tract cancer as a first treatment.

  Recruiting Phase 2 Shanghai Zhongshan Hospital · Shanghai · NCT07733115

• Can family members spot delirium signs in ICU patients?

  Family members who know the patient well try a quick delirium check after visiting in the ICU, to see if their observations add information beyond routine nurse screenings.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07694687

• Aspirin by itself after TAVR for pure aortic regurgitation

  In people with severe aortic regurgitation who have had TAVR and do not need long-term anticoagulation, this study tests whether aspirin alone for a year is safer and as effective as a short course of warfarin followed by aspirin.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07677410

• Isatuximab-VRd for transplant-ineligible newly diagnosed multiple myeloma

  This study tests Isa-VRd in real-world Chinese patients who are newly diagnosed and cannot undergo stem cell transplant to see how well it works and how safe it is.

  Recruiting at 13 sites Shanghai Zhongshan Hospital · Beijing, Beijing Municipality and 12 other locations · NCT07663253

• Tec Dara for newly diagnosed multiple myeloma with light chain amyloidosis

  This study tests whether tec listamab plus daratumumab can help newly diagnosed multiple myeloma with AL amyloidosis and whether the combination is safe.

  Recruiting Phase 2 Shanghai Zhongshan Hospital · Shanghai · NCT07638683

• AI-assisted chest CT report drafting to save radiologist time

  This study tests whether an AI draft report can help experienced chest radiologists write chest CT reports faster without sacrificing quality.

  Recruiting at 2 sites Shanghai Zhongshan Hospital · Shanghai and 1 other locations · NCT07634861

• Glp-1/FGF21 dual agonist for PCOS treatment

  This study tests a GLP-1/FGF21 dual agonist to see if it helps women with PCOS by improving weight, hormones, and menstrual health.

  Recruiting Phase 2 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07616037

• CD160-Enhanced Autologous T Cells for Advanced Biliary Tract Cancer

  This trial tests a patient‑made T cell therapy (BTC-Ag-T) to see if it is safe and can help people with advanced biliary tract cancer who have exhausted standard treatments.

  Recruiting Phase 1 Shanghai Zhongshan Hospital · Shanghai · NCT07614061

• Effect of hyperemic state on angiography-derived microcirculatory resistance

  This study tests whether Angio-IMR values from five software programs, measured at three different states (rest, nitroglycerin sub-hyperemia, and maximal adenosine hyperemia), accurately diagnose coronary microvascular disease in patients with stable angina or suspected CAD.

  Recruiting at 2 sites Shanghai Zhongshan Hospital · Shanghai, Please Select and 1 other locations · NCT07613996

• Chidamide plus chemotherapy and immunotherapy for advanced intrahepatic cholangiocarcinoma

  This trial will test whether adding the oral drug chidamide to gemcitabine/cisplatin and an immune checkpoint inhibitor helps people with unresectable or metastatic intrahepatic cholangiocarcinoma who have not had prior systemic therapy.

  Recruiting Phase 2 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07570849

• Predictive model using CT scans, blood tests, and pathology to forecast pancreatic cancer outcomes

  This project will try to see if combining CT scans, blood tests, and pathology reports can better predict outcomes for adults who had surgery for pancreatic cancer.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07561814

• Single-dose inhaled rh-KGF-2 for ARDS in adults

  This trial tests whether a single inhaled dose of rh-KGF-2 helps adults with ARDS who are on ventilators, using three dose levels to see which is safest and potentially most effective.

  Recruiting Early Phase 1 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07558538

• Chronic Stress and Pancreatic Cancer Outcomes in People with Pancreatic Cancer

  This study tests whether ongoing psychological stress affects how pancreatic cancer behaves and responds to treatment in adults.

  Recruiting Shanghai Zhongshan Hospital · Changsha, Hunan and 2 other locations · NCT07529626

• Allogeneic anti-CD7 CAR-T therapy for type 1 diabetes

  This trial will test an off-the-shelf anti-CD7 CAR-T cell therapy in adults 18–40 with stage 2 or 3 type 1 diabetes to see if it can safely reduce the immune attack on insulin-producing beta cells.

  Recruiting Early Phase 1 Shanghai Zhongshan Hospital · Shanghai · NCT07528105

• Lifestyle program plus low-dose mazdutide to keep weight off

  This study tests whether a year of intensive lifestyle changes, once-weekly low-dose mazdutide (3.0 mg), or both can help adults with obesity maintain weight loss achieved with high-dose mazdutide.

  Recruiting at 13 sites Shanghai Zhongshan Hospital · Chongqing, Chongqing Municipality and 12 other locations · NCT07517042

• Valsalva blood pressure drop and obstruction of the heart's outflow tract

  This project will test whether non-invasive blood pressure waveforms during Valsalva maneuvers can tell if adults with hypertrophic cardiomyopathy have left ventricular outflow tract obstruction.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07483125

• Factors that affect reopening of blocked portal veins in people with cirrhosis and gastroesophageal varices

  This project looks at past records and follow-up to see which factors are linked with reopening (recanalization) of blocked portal veins in people who have cirrhosis and endoscopy-confirmed gastroesophageal varices.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07473375

• Portal hypertension biobank for esophagogastric varices

  This project will try to collect clinical data, CT images, and biological samples from people with portal hypertension and esophagogastric varices to support multi-omics studies and better-tailored care.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07419724

• Portal hypertension with esophagogastric varices: endoscopic treatment vs. non-endoscopic care

  This study tests whether endoscopic treatment helps people with portal hypertension and varices compared to those who don’t get endoscopic therapy.

  Recruiting Shanghai Zhongshan Hospital · Shanghai · NCT07358663

• In vivo CAR-T treatment for refractory Graves' disease

  This trial will test HN2301, an in‑body CAR‑T therapy, to see if it can control thyroid autoimmunity in adults whose Graves' disease has not responded to standard antithyroid drugs.

  Recruiting Early Phase 1 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07333677

• Montelukast to protect the heart after an anterior STEMI

  This trial will test whether giving montelukast around the time of primary PCI can reduce heart damage and later heart failure in adults with anterior STEMI.

  Recruiting at 12 sites Phase 3 Shanghai Zhongshan Hospital · Dalian, Liaoning and 11 other locations · NCT07320625

• Neoadjuvant chemoimmunotherapy followed by endoscopic removal for esophageal squamous cell carcinoma

  This trial tests whether giving chemotherapy plus the PD‑1 drug tislelizumab before surgery can shrink esophageal squamous cell cancers enough to allow removal with an organ‑preserving endoscopic procedure in adults with potentially resectable tumors.

  Recruiting Phase 1 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07317609

• NALIRIFOX plus targeted therapy versus FOLFOX plus targeted therapy for first-line metastatic colorectal cancer

  This study tests whether NALIRIFOX combined with a targeted drug works better and is safe compared with FOLFOX plus targeted therapy as the first treatment for adults with inoperable metastatic colorectal cancer.

  Recruiting Phase 3 Shanghai Zhongshan Hospital · Shanghai · NCT07309289

• iGlarLixi vs standard diabetes care in adults with Type 2 diabetes in China

  This study tests whether iGlarLixi works better and is as safe as standard diabetes care for adults in China who aren’t well controlled on 1–3 oral drugs.

  Recruiting at 24 sites Phase 4 Shanghai Zhongshan Hospital · Hefei, Anhui and 23 other locations · NCT07307235

• Gemcitabine and cisplatin plus PD‑1/PD‑L1 immunotherapy for advanced cholangiocarcinoma

  It will try combining standard gemcitabine-plus-cisplatin chemotherapy with a PD‑1/PD‑L1 immunotherapy for adults with advanced, unresectable or metastatic cholangiocarcinoma.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07291063

• Drug‑coated balloon versus drug‑eluting stent for severely calcified coronary arteries after calcium modification

  This study tests whether drug‑coated balloons work as well as drug‑eluting stents for adults with severe coronary artery calcification after the artery has been treated to modify the calcium.

  Recruiting Shanghai Zhongshan Hospital · Shanghai · NCT07277114

• Surufatinib for adults with advanced neuroendocrine neoplasms in routine care

  This study will see if daily oral surufatinib, given alone or with other treatments, helps adults with advanced neuroendocrine tumors when used in regular clinical practice.

  Recruiting at 4 sites Phase 4 Shanghai Zhongshan Hospital · Shanghai and 3 other locations · NCT07272512

• Envafolimab with albumin-bound paclitaxel and carboplatin before surgery for resectable locally advanced esophageal squamous cell carcinoma

  This study tests whether adding envafolimab to albumin-bound paclitaxel and carboplatin before surgery helps people with resectable locally advanced esophageal squamous cell carcinoma.

  Recruiting Phase 2 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07266493

• Allogeneic dual CD19/BCMA CAR-T therapy for refractory Graves' disease

  This will test an off-the-shelf CAR-T treatment that targets CD19 and BCMA to see if it can produce lasting remission in people whose Graves' disease has not responded to standard medications.

  Recruiting Early Phase 1 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07261345

• Asiaticoside treatment for adults with overweight or obesity

  This study will try oral asiaticoside tablets to see if they help adults with overweight or obesity lose weight and improve related metabolic measures.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07241533

• Do airway mucus plugs cause lung scarring in people with COPD undergoing lung cancer surgery

  This study will see if airway mucus plugs in people with COPD are linked to lung scarring by analyzing lung tissue and mucus collected during lung cancer operations.

  Recruiting Shanghai Zhongshan Hospital · Shanghai · NCT07236541

• Very early PCSK9 inhibition after a heart attack

  This project will try giving a PCSK9 inhibitor soon after a heart attack to people with multivessel coronary disease to see if it stabilizes vulnerable plaques and lowers the chance of another heart event.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07208006

• Balanced gelatin versus crystalloid therapy for perioperative sepsis in emergency abdominal surgery

  This study will test if a balanced gelatin solution helps adults with sepsis undergoing emergency abdominal surgery keep blood volume and recover better than Ringer's acetate.

  Recruiting Phase 4 Shanghai Zhongshan Hospital · Guangzhou, Guangdong and 8 other locations · NCT07172451

• High-resolution coronary CT for plaque biomechanics and heart function

  This trial tests whether a new high-temporal-resolution coronary CT scan can noninvasively measure plaque vulnerability and heart function in adults with known or suspected coronary artery disease or type 2 diabetes.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07169201

• Real-world look at severe respiratory failure (ARDS)

  This project will collect real-world data on adults at high risk for ARDS to see which clinical factors predict worse outcomes.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07165717

• High-flow nasal oxygen versus face mask oxygen for sedated gastroscopy in people with visceral obesity

  This test sees if using high-flow nasal oxygen instead of a standard face mask keeps oxygen levels better during sedated gastroscopy for people with visceral obesity.

  Recruiting Shanghai Zhongshan Hospital · Shanghai · NCT07159022

• Sivelestat treatment to protect organs after surgery for type A aortic dissection

  In this multicenter trial, patients after surgery for type A aortic dissection receive sivelestat or a placebo to see if it helps protect organ function.

  Recruiting Phase 4 Shanghai Zhongshan Hospital · Hefei, Anhui and 6 other locations · NCT07156656

• Using a steerable VitaFlow Liberty Flex catheter to deliver transcatheter aortic valves in patients with difficult aortic anatomy

  This study will test whether the steerable VitaFlow Liberty Flex delivery system helps doctors place transcatheter aortic valves more safely in people with severe aortic stenosis and challenging aortic-left ventricular angles (>60°).

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07145463

• Allogeneic anti‑CD19 CAR‑T therapy for refractory Graves' disease

  This will try a single dose of donor‑derived anti‑CD19 CAR‑T cells to lower TSH‑receptor antibodies and control hyperthyroidism in people whose Graves' disease has not responded to standard treatments.

  Recruiting Early Phase 1 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07129642

• µQFR to check side‑branch narrowing after a single stent in bifurcation coronary arteries

  This study will test whether µQFR from a single angiographic view can correctly detect functionally important side‑branch narrowing after single‑stent treatment in adults with obstructive coronary artery disease involving bifurcations.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07116083

• Using patient-derived tumor organoids to predict pre-surgery treatment response in resectable esophageal squamous cell carcinoma

  This project will test whether lab-grown mini-tumors made from each patient's own cancer can predict how their resectable esophageal squamous cell carcinoma will respond to personalized pre-surgery chemotherapy or chemo‑immunotherapy.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07054086

• Glofitamab, Polatuzumab Vedotin and Zanubrutinib in First-line Elderly DLBCL

  A group of elderly patients with newly diagnosed diffuse large B-cell lymphoma will try a lighter chemotherapy approach using three targeted drugs to see if it works and is safe.

  Recruiting Phase 2 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07012980

• Dihydroartemisinin with minoxidil for female androgenetic alopecia

  This trial will test whether taking oral dihydroartemisinin along with topical minoxidil helps increase terminal hairs on the top of the head in adult women with androgenetic alopecia.

  Recruiting Early Phase 1 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07012486

• Dihydroartemisinin for treating acne vulgaris

  This study will test whether taking dihydroartemisinin every day for three months can reduce acne severity in adults with acne vulgaris.

  Recruiting Early Phase 1 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07007078

• Comparing SMILE and SMILE Xtra procedures for myopia treatment

  This study is testing which of two eye surgeries, SMILE or SMILE Xtra, works better for treating nearsightedness and keeping your vision stable.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06992011

• Comparing the effectiveness of two treatments for myopia

  This study is testing which of two eye surgeries, SMILE or SMILE Xtra, works better for people aged 18 to 50 with high myopia to improve their vision and keep it stable over time.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06973278

• Improving treatment strategies for bleeding from esophageal varices in portal hypertension

  This study is trying to find better ways to treat bleeding from swollen veins in the esophagus for people with portal hypertension by personalizing treatment based on their specific conditions.

  Recruiting at 10 sites Shanghai Zhongshan Hospital · Guangzhou, Guangdong and 9 other locations · NCT06970509

• Examining breath markers in liver disease patients

  This study is trying to see if certain breath markers can help identify and understand the progression of liver disease in patients, especially those with cirrhosis.

  Recruiting at 3 sites Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality and 2 other locations · NCT06968234

• Combining CT Angiography and Perfusion for Heart Disease Assessment

  This study is testing if using a combination of advanced heart imaging techniques can help doctors better understand and treat people with coronary artery disease.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06949150

• Combining heated chemotherapy with intravenous chemotherapy for pancreatic cancer spread in the abdomen

  This study is testing if a new combination of heated chemotherapy and regular chemotherapy can help people with advanced pancreatic cancer live longer and stay safe during treatment.

  Recruiting Phase 2 Shanghai Zhongshan Hospital · Changsha, Hunan and 1 other locations · NCT06946901

• Investigating how sleep disorders affect lung cancer and immune response

  This study is trying to see how sleep problems like insomnia and sleep apnea affect the immune system and treatment outcomes in people who have just been diagnosed with lung cancer.

  Recruiting Shanghai Zhongshan Hospital · Shanghai · NCT06941948

• HRS-4642 with immunotherapy and chemotherapy for pancreatic cancer

  This study tests whether adding HRS-4642 to immunotherapy and chemotherapy helps people with pancreatic cancer whose disease is advanced or borderline resectable.

  Recruiting Phase 2 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06938282

• Residual plaque risk during intensive cholesterol‑lowering in coronary heart disease

  This project will follow people with coronary heart disease on intensive cholesterol‑lowering treatment to see if leftover lipid and inflammatory risks are linked to coronary plaque getting worse.

  Recruiting Shanghai Zhongshan Hospital · Shanghai · NCT06936111

• Effects of a Low Valine Diet on Weight and Metabolism

  This study is testing if meal replacements with less valine can help overweight and obese people lose weight and improve their metabolism compared to regular meal replacements.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06883578

• Radiotherapy for patients with oligoprogressive liver cancer after PD-1 therapy

  This study is testing if adding radiation therapy can help people with liver cancer who have had some success with PD-1 therapy but are starting to see their cancer progress.

  Recruiting Phase 2 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06870942

• Using Dihydroartemisinin to treat Polycystic Ovary Syndrome

  This study is testing if a medication called dihydroartemisinin can help women with Polycystic Ovary Syndrome (PCOS) feel better by improving their menstrual cycles and hormone levels.

  Recruiting at 4 sites Phase 2 Shanghai Zhongshan Hospital · Xiamen, Fujian and 3 other locations · NCT06842524

• Camrelizumab with Rivoceranib and HAIC as conversion therapy for potentially resectable liver cancer

  This study tests whether adding hepatic arterial infusion chemotherapy to camrelizumab and rivoceranib helps shrink liver tumors enough to allow surgical removal in people with potentially resectable hepatocellular carcinoma.

  Recruiting at 2 sites Phase 2/3 Shanghai Zhongshan Hospital · Harbin, Heilongjiang and 1 other locations · NCT06796803

• Multimodal ablation with Tislelizumab, lenvatinib and TACE for unresectable primary liver cancer

  This trial will test whether combining multimodal ablation with Tislelizumab (a PD‑1 antibody), lenvatinib, and TACE helps people with unresectable primary liver cancer.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06794073

• Registry of Plasma Cell Dyscrasia

  This study is collecting and looking at health information from patients with plasma cell dyscrasia to better understand their disease and how it affects them.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06760052

• Using enarodustat to correct anemia in adults with non-dialysis chronic kidney disease

  This test gives enarodustat to adults with non-dialysis chronic kidney disease and anemia to see if aiming for a higher hemoglobin (13 g/dL) versus a lower hemoglobin (11 g/dL) improves quality of life and is safe.

  Recruiting Phase 4 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06725810

• Investigating molecular differences in invasive pituitary tumors

  This study is trying to find out what makes invasive pituitary tumors more aggressive by looking at tumor samples from patients and comparing their molecular differences.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06705036

• Effects of High-Frequency Oscillatory Ventilation in ICU Patients

  This study is testing whether a new breathing treatment called Continuous High-Frequency Oscillatory Ventilation can improve lung function and comfort for awake ICU patients with collapsed lungs.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06702813

• Observing exhaled nitric oxide levels in ICU patients with respiratory failure

  This study looks at the levels of a gas called nitric oxide in the breath of ICU patients with breathing problems to see how it changes over time and how it relates to their treatment.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06680895

• Predicting treatment response in gastric cancer using immune markers

  This study is trying to find out if certain immune markers in the blood can help doctors predict how well advanced gastric cancer patients will respond to chemotherapy and immunotherapy.

  Recruiting Shanghai Zhongshan Hospital · Xuhui District, Shanghai Municipality · NCT06662110

• NIRS-OCT imaging to find vulnerable coronary plaques in people with diabetes

  This project will test whether a new combined NIRS-OCT index (maxLCBI4mm/FCTmin) can identify vulnerable coronary plaques in adults with diabetes who are undergoing coronary OCT.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06649305

• Combining benmelstobart with radiochemotherapy for esophageal cancer treatment

  This study is testing if adding a new drug called benmelstobart to standard radiation and chemotherapy can help people with esophageal cancer have better treatment outcomes before surgery.

  Recruiting at 5 sites Phase 2 Shanghai Zhongshan Hospital · Shantou, Guangdong and 4 other locations · NCT06637163

• Exercise effects on metabolism and blood-cell networks in people with prediabetes

  This 8-week exercise program will try to improve weight, lab measures, and blood-cell and metabolic biomarkers in overweight or obese adults with prediabetes.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06633575

• Treatment of advanced biliary tract tumors with HRS-4642 alone or with adebrelimab

  This study is testing if a new treatment called HRS-4642, alone or with another drug called adebrelimab, can help people with advanced biliary tract cancer who haven't had success with other treatments.

  Recruiting Phase 2 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06620848

• Using a new device to treat severe pulmonary arterial hypertension

  This study is testing a new device to see if it can help people with severe pulmonary arterial hypertension live longer and avoid hospital visits.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06605794

• Evaluating LM-302 with Candonilimab and Capecitabine for Advanced Gastric Cancer

  This study is testing a new combination of treatments for people with advanced stomach cancer to see if it can help them fight the disease better.

  Recruiting Phase 2 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06587425

• Combination treatment for advanced liver cancer using anti-PD-1/PD-L1 and anti-VEGF antibodies

  This study is testing a new combination treatment for adults with advanced liver cancer to see if it helps improve their health and outcomes.

  Recruiting Shanghai Zhongshan Hospital · Shanghai · NCT06537908

• Comparing precision treatment to conventional treatment for Takayasu's arteritis

  This study is testing if a personalized treatment plan for Takayasu's arteritis works better than standard treatment for people with this condition.

  Recruiting Phase 4 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06498089

• Treatment of immune thrombocytopenia with hydroxychloroquine and dexamethasone

  This study is testing if a combination of hydroxychloroquine and dexamethasone can help adults with immune thrombocytopenia feel better compared to just using dexamethasone alone.

  Recruiting at 7 sites Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality and 6 other locations · NCT06479317

• Treatment of immune thrombocytopenia with hydroxychloroquine and prednisone

  This study is testing if a combination of hydroxychloroquine and prednisone can help adults with immune thrombocytopenia feel better and have longer-lasting results than just using prednisone alone.

  Recruiting at 7 sites Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality and 6 other locations · NCT06479304

• Treatment of immune thrombocytopenia with hydroxychloroquine and TPO-RA

  This study is testing if adding hydroxychloroquine to a standard treatment can help adults with immune thrombocytopenia who have certain antibodies feel better and have better platelet levels.

  Recruiting at 7 sites Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality and 6 other locations · NCT06479291

• Combining PD-1 antibody and chemotherapy followed by surgery for limited metastatic gastric cancer

  This study tests if combining immunotherapy and chemotherapy with surgery can help people with limited metastatic gastric cancer live longer and feel better compared to just using the treatments without surgery.

  Recruiting Phase 2 Shanghai Zhongshan Hospital · Shanghai, Shanghai City and 1 other locations · NCT06468280

• Indobufen versus aspirin after coronary stent in older adults with acute coronary syndrome

  This test will see if using indobufen instead of aspirin, both given with ticagrelor, is as effective and safer over one year for people over 65 who received a drug‑eluting coronary stent after an acute coronary syndrome.

  Recruiting Phase 4 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06451198

• Using fecal microbiota transplantation to treat constipation in Parkinson's disease

  This study is testing whether a treatment using gut bacteria from healthy donors can help people with Parkinson's disease who struggle with constipation.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06388863

• Study of biomarkers in liver cancer after surgery

  This study looks at blood samples from liver cancer patients who had surgery to see if certain markers can help predict their long-term health and guide their treatment.

  Recruiting Shanghai Zhongshan Hospital · Shanghai · NCT06382103

• External drainage methods for pancreatic surgery complications

  This study is testing whether using external drainage methods after pancreatic surgery can help prevent complications like leaks and improve recovery for patients with pancreatic tumors.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06322680

• 24-hour IV lidocaine to reduce lung complications after emergency abdominal surgery for infection

  This will try a 24-hour continuous intravenous lidocaine infusion to see if it lowers postoperative lung complications in adults having emergency laparotomy for intra-abdominal infection.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06304779

• Registry for patients with complex coronary lesions undergoing PCI

  This study is testing if using special ultrasound tools during heart procedures can help people with complex coronary blockages feel better and stay healthy for longer.

  Recruiting Shanghai Zhongshan Hospital · Shanghai · NCT06274645

• Exploring the link between carotid atherosclerosis and coronary artery disease

  This study looks at whether the buildup of plaque in the neck arteries is linked to heart artery disease in patients who have chest pain or tightness.

  Recruiting Shanghai Zhongshan Hospital · Shanghai · NCT06253962

• Understanding the causes and outcomes of lymphoma in Chinese patients

  This study looks at the clinical and genetic details of lymphoma patients in China to see how these factors affect the disease and its outcomes.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06203652

• Furmonertinib before surgery for stage II–IIIB EGFR-mutant NSCLC

  This study tests whether giving furmonertinib before surgery can help shrink tumors in adults with resectable EGFR-mutant non-small cell lung cancer.

  Recruiting Phase 2 Shanghai Zhongshan Hospital · Shanghai · NCT05987826

• Screening for M-protein in relatives of multiple myeloma patients in China

  This study is trying to see if screening for a specific protein in the blood can help find early signs of a blood condition in family members of people with multiple myeloma in China.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT05965115

• Evaluating a noninvasive method to measure blood flow in cardiac surgery patients

  This study is testing a new, noninvasive way to measure blood flow during heart surgery to see if it works as well as the traditional method for patients on ventilators.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT05944146

• Neoadjuvant anti-PD-1 plus chemotherapy for esophageal cancer

  This study is testing if combining a new immune therapy with chemotherapy can help people with advanced esophageal cancer do better and live longer.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT05740995

• Fecal microbiota transplant for adults with refractory irritable bowel syndrome

  This project will try monthly fecal microbiota transplants—given as oral capsules or through a tube to the small intestine—to see if symptoms improve in adults (18–70) with IBS who haven't responded to at least three treatments.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT05740319

• Organ preservation approach for early low rectal cancer

  This study is testing a new treatment plan for early low rectal cancer that combines chemotherapy and radiation with less invasive surgery to see if it can help patients keep their organs and improve their quality of life.

  Recruiting Phase 2 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT05563922

• Observational registry on reconstruction methods after stomach surgery

  This study looks at different ways to rebuild the stomach after surgery for cancer to see which method helps patients recover better and feel good.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT05539105

• Evaluating the effectiveness of endovascular treatment for aortoiliac occlusive disease

  This study is testing how well a new endovascular treatment works for people with aortoiliac occlusive disease over the long term.

  Recruiting Shanghai Zhongshan Hospital · Shanghai · NCT05391815

• Observing coronary artery disease through CT angiography

  This study looks at how coronary artery disease develops in patients getting a special heart scan to see if certain plaque features can help predict heart problems in the future.

  Recruiting Shanghai Zhongshan Hospital · Shanghai · NCT05380622

• Implementing diabetes treatment guidelines by primary care physicians in the community

  This study is testing whether following new diabetes treatment guidelines can help older adults with diabetes avoid serious heart and kidney problems compared to regular care.

  Recruiting at 13 sites Shanghai Zhongshan Hospital · Suzhou, Jaingsu and 12 other locations · NCT05349955

• Detecting peritoneal metastasis in gastric cancer using blood tests

  This study is testing whether blood tests can help find peritoneal metastasis in people with gastric cancer more easily than current methods.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT05347524

• Combining immunotherapy with chemoradiotherapy for advanced esophageal cancer

  This study is testing if adding a new immunotherapy drug to standard treatment can help people with advanced esophageal cancer do better before surgery.

  Recruiting Phase 2/3 Shanghai Zhongshan Hospital · Shanghai · NCT04973306

• Evaluating ablation therapy for lung cancer with ground-glass nodules

  This study is testing if a special treatment called ablation therapy can help people with lung cancer that shows up as ground-glass nodules when they can't have regular surgery.

  Recruiting Phase 2 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT04905056

• Comparing laparoscopic and open surgery for advanced stomach cancer

  This study is testing whether laparoscopic surgery is better than open surgery for people with advanced stomach cancer in terms of recovery and long-term health outcomes.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT04710758

• Examining lymph node dissection methods for small lung nodules

  This study is testing different surgical methods for removing lymph nodes in patients with small lung nodules to see which approach helps them recover better after surgery.

  Recruiting Shanghai Zhongshan Hospital · Shanghai · NCT04581122

• Investigating cardiovascular disease risk factors in elderly diabetic patients

  This study looks at how common heart disease risk factors are in older people with diabetes to see how they manage their health over ten years.

  Recruiting Shanghai Zhongshan Hospital · Suzhou, Jiangsu · NCT04544527

• Evaluating treatments for severe Takayasu arteritis

  This study tests whether tocilizumab or adalimumab is more effective for people with severe Takayasu arteritis to help tailor treatments based on their specific needs.

  Recruiting Phase 4 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT04300686

Quick answers

How many clinical trials run by Shanghai Zhongshan Hospital are recruiting right now?

111, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in China (111 trials), Hong Kong (3 trials), Macau (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 17, Phase 4: 9, Early Phase 1: 7, Phase 2/3: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →