Improving treatment strategies for bleeding from esophageal varices in portal hypertension

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on enhancing the treatment of esophageal varices in patients with portal hypertension by developing an individualized treatment model. It assesses the vascular characteristics of esophagogastric varices using imaging techniques like portal venous CT and ultrasound, alongside clinical data. The goal is to stratify patient risks and provide tailored treatment options to reduce the high rebleeding rates associated with current methods. By understanding the anatomical and hemodynamic factors affecting treatment outcomes, the study aims to improve patient care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Confirmed diagnosis of portal hypertension;
2. Underwent imaging and endoscopic examination or treatment within one week after admission;
3. Endoscopy revealed the presence of esophageal and/or gastric varices.

Exclusion Criteria:

1. CT image slice thickness does not meet the requirements or there are artifacts;
2. Endoscopy shows no presence of esophageal and/or gastric varices;
3. Presence of severe life-threatening diseases of the circulatory, hematological, or respiratory systems;
4. Lack of important historical medical information or other relevant data.

Where it's running

• Southern Medical University Nanfang Hospital
  Guangzhou, Guangdong, China Recruiting
• The Third Affiliated Hospital of Sun Yat-sen University
  Guangzhou, Guangdong, China Recruiting
• The First Affiliated Hospital of Nanchang University
  Nanchang, Jiangxi, China Recruiting
• People's Liberation Army Northern Theater General Hospital
  Shenyang, Liaoning, China Recruiting
• Qilu Hospital of Shandong University
  Jinan, Shandong, China Recruiting
• Shandong Provincial Hospital
  Jinan, Shandong, China Recruiting

Study contacts

• Principal investigator: Shiyao Chen, Ph.D. — Shanghai Zhongshan Hospital
• Study coordinator: Yiting Wang, Ph.D.
• Email: wang.yiting@zs-hospital.sh.cn
• Phone: +86-15221919860

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.