Investigating molecular differences in invasive pituitary tumors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study collects paired tumor samples from the intrasellar and cavernous sinus regions of 20 patients with invasive pituitary tumors. The samples are preserved for multi-omics analysis, including proteomics and transcriptomics, to identify molecular differences that may drive tumor aggressiveness. Imaging data from MRI and CT scans will assess tumor morphology and invasion, while in vitro experiments will validate key findings. The goal is to uncover biomarkers and pathways associated with tumor invasiveness and regional specificity.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Invasive pituitary tumors involving the cavernous sinus
2. Retrospective inclusion of patients who have signed informed consent forms for the donation of biological samples and health-related information
3. Age range: 18-80 years
4. Subjects are willing to participate in this study

Exclusion Criteria:

1. Non-invasive pituitary tumors
2. Pregnant or breastfeeding
3. Other conditions deemed unsuitable for participation in this clinical trial as assessed by the physician

Where it's running

• Zhongshan Hospital Fudan University
  Shanghai, Shanghai Municipality, China Recruiting

Study contacts

• Study coordinator: Tao Xie
• Email: xie.tao@zs-hospital.sh.cn
• Phone: +8613524281211

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.