High-resolution coronary CT for plaque biomechanics and heart function

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective observational study uses the uCT SiriuX Pro, an ultra-high-temporal-resolution cardiac CT platform, to derive CT-based radial wall strain (CT-RWS), a CT systolic flow perfusion index (CT-SFPR), and dynamic CT ejection fraction (CT-EF) in high-risk patients. CT-RWS will be compared with invasive optical coherence tomography (OCT) plaque features and clinical outcomes to determine diagnostic and prognostic performance. CT-SFPR will be compared with nuclear perfusion imaging to evaluate the hemodynamic relevance of myocardial bridging, and CT-EF will be compared with transthoracic echocardiography to test feasibility and accuracy. The study enrolls adults with suspected or known coronary artery disease or type 2 diabetes who can undergo CTA and angiography and is conducted at Zhongshan Hospital Fudan University in Shanghai.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults ≥18 years with suspected or known CAD or with type 2 diabetes

Exclusion Criteria:

* those can not undergo CTA and angiography

Where it's running

• Zhongshan Hospital Fudan University
  Shanghai, Shanghai Municipality, China Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.