Observing coronary artery disease through CT angiography

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to analyze the development and characteristics of coronary atherosclerotic plaques in patients referred for coronary computed tomography angiography (CCTA). It will track the natural history of plaque progression or regression over time, identify precursors of plaques that may lead to acute or chronic coronary syndromes, and assess the prognostic implications of various plaque features and treatment strategies. The study will utilize advanced imaging techniques to gather detailed physiological and anatomical data on coronary lesions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with an indication for CCTA.
* Qualified patients who have signed a written informed consent form.

Exclusion Criteria:

* Left ventricular ejection fraction \< 35%
* Acute ST-elevation myocardial infarction within 72 hours or previous coronary artery bypass graft surgery
* Abnormal epicardial coronary flow (TIMI flow \< 3)
* Planned coronary artery bypass graft surgery after diagnostic angiography
* Poor quality of CCTA or other reasons by core lab that are unsuitable for plaque, physiological or fat analysis
* Patients with a stent in the target vessel

Where it's running

• Shanghai Zhongshan Hospital
  Shanghai, China Recruiting

Study contacts

• Study coordinator: Neng Dai, MD
• Email: niceday1987@hotmail.com
• Phone: +8613701997266

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.