Study of biomarkers in liver cancer after surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to analyze blood samples from patients with hepatocellular carcinoma (HCC) who have undergone surgical resection. It focuses on identifying circulating tumor DNA (ctDNA) and plasma protein levels to enhance the prediction of long-term prognosis and inform treatment options. By monitoring ctDNA and conducting plasma proteomic analysis, the study seeks to improve patient outcomes following surgery. The findings could lead to more personalized treatment strategies for HCC patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with a first diagnosis of HCC.
* Patients with HCC who are to undergo surgical treatment, with or without neoadjuvant therapy.
* Ability to obtain tissue sample for ctDNA analysis and detectable baseline ctDNA level.

Exclusion Criteria:

* Patients with secondary liver cancer, or intrahepatic cholangiocarcinoma.
* Any other concurrent malignancy.
* History of organ transplant or hepatic encephalopathy.

Where it's running

• Zhongshan Hospital Fudan University
  Shanghai, China Recruiting

Study contacts

• Study coordinator: Huichuan Sun
• Email: sun.huichuan@zs-hospital.sh.cn
• Phone: +86-21-64041990

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.