Investigating how sleep disorders affect lung cancer and immune response

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective observational cohort study aims to explore the relationship between sleep disorders, such as insomnia and obstructive sleep apnea, and the tumor immune microenvironment in patients with lung cancer. It will involve newly diagnosed primary lung cancer patients who will be stratified based on their sleep disorder status, confirmed through polysomnography and validated questionnaires. The study will follow participants for three years to assess how these disorders impact immunotherapy responses and long-term clinical outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with newly diagnosed stage III-IV non-small-cell lung cancer (NSCLC) not receiving systemic therapy (chemotherapy, immunotherapy, or radiotherapy)

Exclusion Criteria:

* Patients with severe mental illness, other malignant tumors, or receiving sleep medication

Where it's running

• Zhong Shan hospital
  Shanghai, China Recruiting

Study contacts

• Study coordinator: Pan Jiang, Phd
• Email: jiang.pan@zs-hospital.sh.cn
• Phone: 18201731016

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.