Clinical trial Recruiting at 1 site Early Phase 1 Interventional Ages 18 to 40 Women only

Dihydroartemisinin with minoxidil for female androgenetic alopecia

Official title: A Pilot Study to Evaluate the Therapeutic Effect of Dihydroartemisinin on Female Androgenetic Alopecia

Run by Shanghai Zhongshan Hospital · NCT07012486 · Data updated 2026-11-12

This trial will test whether taking oral dihydroartemisinin along with topical minoxidil helps increase terminal hairs on the top of the head in adult women with androgenetic alopecia.

More Androgenetic Alopecia (AGA) trials

Quick facts

PhaseEarly Phase 1
Study typeInterventional
Ages18 Years to 40 Years
SexWomen only
Enrollment30 (estimated)
SponsorShanghai Zhongshan Hospital
Academic / other
Locations1 site (Shanghai, Shanghai Municipality)
StatusRecruiting
StartedJune 2025
Main results expectedMay 2026
Study endsDecember 2026
Registry record updatedJune 10, 2025
Trial IDNCT07012486 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adult women with clinically diagnosed androgenetic alopecia who are not planning pregnancy within six months and meet the study's safety criteria are ideal candidates.

Probably not a fit

Patients who are pregnant or breastfeeding, have recent use of systemic or topical hair-loss drugs, or have severe organ disease or malignancy may not benefit or be eligible.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adult women with clinically diagnosed androgenetic alopecia will receive either daily oral dihydroartemisinin plus topical 5% minoxidil or topical 5% minoxidil alone for six months. Participants will attend the clinic once monthly for checkups and tests. The main outcome is change in terminal hair follicles in the vertex (top) scalp area. The comparison aims to determine whether adding dihydroartemisinin improves hair growth beyond minoxidil alone.

Why it matters

Potential benefit: If successful, adding dihydroartemisinin could increase visible hair density on the scalp compared with minoxidil alone.

How similar studies have gone: Using dihydroartemisinin for hair loss is largely novel with limited prior clinical evidence in humans.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Clinically diagnosed with androgenetic alopecia (AGA)
* No pregnancy plans within the next 6 months

Exclusion Criteria:

* Patients who received systemic medications for hair loss within the past 2 months
* Use of topical medication for hair loss within the past 2 weeks
* Pregnancy or lactation
* Patients with known severe diseases of vital organs (e.g., heart, liver, kidney) or malignancies.

Where it's running

  • Zhongshan Hospital Fudan University
    Shanghai, Shanghai Municipality, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.