Dihydroartemisinin with minoxidil for female androgenetic alopecia
Official title: A Pilot Study to Evaluate the Therapeutic Effect of Dihydroartemisinin on Female Androgenetic Alopecia
Run by Shanghai Zhongshan Hospital · NCT07012486 · Data updated 2026-11-12
This trial will test whether taking oral dihydroartemisinin along with topical minoxidil helps increase terminal hairs on the top of the head in adult women with androgenetic alopecia.
Quick facts
| Phase | Early Phase 1 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years to 40 Years |
| Sex | Women only |
| Enrollment | 30 (estimated) |
| Sponsor | Shanghai Zhongshan Hospital Academic / other |
| Locations | 1 site (Shanghai, Shanghai Municipality) |
| Status | Recruiting |
| Started | June 2025 |
| Main results expected | May 2026 |
| Study ends | December 2026 |
| Registry record updated | June 10, 2025 |
| Trial ID | NCT07012486 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adult women with clinically diagnosed androgenetic alopecia who are not planning pregnancy within six months and meet the study's safety criteria are ideal candidates.
✕Probably not a fit
Patients who are pregnant or breastfeeding, have recent use of systemic or topical hair-loss drugs, or have severe organ disease or malignancy may not benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adult women with clinically diagnosed androgenetic alopecia will receive either daily oral dihydroartemisinin plus topical 5% minoxidil or topical 5% minoxidil alone for six months. Participants will attend the clinic once monthly for checkups and tests. The main outcome is change in terminal hair follicles in the vertex (top) scalp area. The comparison aims to determine whether adding dihydroartemisinin improves hair growth beyond minoxidil alone.
Why it matters
Potential benefit: If successful, adding dihydroartemisinin could increase visible hair density on the scalp compared with minoxidil alone.
How similar studies have gone: Using dihydroartemisinin for hair loss is largely novel with limited prior clinical evidence in humans.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinically diagnosed with androgenetic alopecia (AGA) * No pregnancy plans within the next 6 months Exclusion Criteria: * Patients who received systemic medications for hair loss within the past 2 months * Use of topical medication for hair loss within the past 2 weeks * Pregnancy or lactation * Patients with known severe diseases of vital organs (e.g., heart, liver, kidney) or malignancies.
Where it's running
-
Zhongshan Hospital Fudan University
Shanghai, Shanghai Municipality, China Recruiting
Study contacts
- Principal investigator: Jingjing JIANG, MD, PhD — Fudan University
- Study coordinator: Lujuan GAO, MD, PhD
- Email: gao.lujuan@zs-hospital.sh.cn
- Phone: 86-021-64041990
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Exosome therapy for male pattern baldness
This trial tests whether injecting hUCMSC-derived exosomes into the scalp can promote hair regrowth in men with androgenetic alopecia, compared with a placebo.
-
Multi-omics view of androgenetic alopecia in scalp tissue
This study tests a multi-omics approach to understand hair follicle biology in men with androgenetic alopecia by comparing affected and healthy scalp tissue.
-
VENEZE peptide hair serum versus 2% topical minoxidil for androgenetic alopecia
This trial tests if VENEZE peptide hair serum helps adults with androgenetic alopecia grow thicker, denser hair compared with 2% topical minoxidil.
-
Topical Lactobacillus reuteri for hair loss due to androgenetic alopecia
This trial will test whether applying a topical Lactobacillus reuteri solution can increase hair count and improve hair quality in adults (18–60) with androgenetic alopecia over 12 months.
-
OLX72021 for men with male-pattern hair loss
This research will test whether OLX72021 is safe and may help men aged 18 to 59 with mild to moderate male-pattern hair loss.
-
ABS-201 for improving hair growth in healthy adults and people with androgenetic alopecia
This trial will test whether ABS-201 is safe and helps hair grow in healthy adults and in men and women with androgenetic alopecia.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.