Examining lymph node dissection methods for small lung nodules
Zhongshan Hospital
This study is testing different surgical methods for removing lymph nodes in patients with small lung nodules to see which approach helps them recover better after surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 1500 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Shanghai Zhongshan Hospital Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Shanghai) |
| Trial ID | NCT04581122 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of various lymph node dissection techniques on the prognosis of ground glass nodules (GGNs) that are smaller than 3 cm and contain more than 50% solid components. It involves multiple centers and aims to determine the most effective surgical approach for improving patient outcomes. Participants will undergo lobectomy and will be monitored for their prognosis following the procedure. The study focuses on patients whose GGNs have not subsided after three months of observation.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 75 with GGNs diagnosed by lung CT that have not decreased in size after three months.
Not a fit: Patients with a history of immunosuppressive or hormonal drug use, or those currently undergoing radiotherapy or chemotherapy, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical strategies that enhance the prognosis for patients with specific types of lung nodules.
How similar studies have performed: While similar studies have explored lymph node dissection techniques, the specific focus on GGNs with these characteristics is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Aged between 18 and 75 years; 2. GGO is diagnosed by lung CT and failure to subside after 3 months (the patient having been re-examined by thin-section CT); 3. The maximum diameter of the GGO is smaller than 3cm; 4. The maximum diameter of the solid component in the GGO is more than 50%; 5. The patient is able to undergo the lobectomy 6. The patient is able to understand and comply with the study and has provided written informed consent. Exclusion Criteria: \- Patients meeting any of the following criteria are not eligible for this trial: 1. Patients with a history of using immunosuppressive or hormonal drugs; 2. Patients receiving radiotherapy or chemotherapy; 3. Patients who fail to comply with our follow-up strategy; 4. Other situations that are not in conformity with the standards and requirements of this trial.
Where this trial is running
Shanghai
- Jiang Wei — Shanghai, China (Recruiting)
Study contacts
- Study coordinator: Jiang Wei, Dr
- Email: jiang.wei1@zs-hospital.sh.cn
- Phone: 86-21-64041990
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.