Clinical trial Recruiting at 1 site Interventional Ages 18 to 75

Examining lymph node dissection methods for small lung nodules

Official title: Zhongshan Hospital

Run by Shanghai Zhongshan Hospital · NCT04581122 · Data updated 2026-11-12

This study is testing different surgical methods for removing lymph nodes in patients with small lung nodules to see which approach helps them recover better after surgery.

Quick facts

Study typeInterventional
Ages18 Years to 75 Years
SexAll
Enrollment1500 (estimated)
SponsorShanghai Zhongshan Hospital
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Shanghai)
StatusRecruiting
StartedSeptember 1, 2020
Main results expectedDecember 31, 2022
Study endsDecember 31, 2028
Registry record updatedOctober 9, 2020
Trial IDNCT04581122 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 to 75 with GGNs diagnosed by lung CT that have not decreased in size after three months.

Probably not a fit

Patients with a history of immunosuppressive or hormonal drug use, or those currently undergoing radiotherapy or chemotherapy, may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the impact of various lymph node dissection techniques on the prognosis of ground glass nodules (GGNs) that are smaller than 3 cm and contain more than 50% solid components. It involves multiple centers and aims to determine the most effective surgical approach for improving patient outcomes. Participants will undergo lobectomy and will be monitored for their prognosis following the procedure. The study focuses on patients whose GGNs have not subsided after three months of observation.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical strategies that enhance the prognosis for patients with specific types of lung nodules.

How similar studies have gone: While similar studies have explored lymph node dissection techniques, the specific focus on GGNs with these characteristics is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Aged between 18 and 75 years;
2. GGO is diagnosed by lung CT and failure to subside after 3 months (the patient having been re-examined by thin-section CT);
3. The maximum diameter of the GGO is smaller than 3cm;
4. The maximum diameter of the solid component in the GGO is more than 50%;
5. The patient is able to undergo the lobectomy
6. The patient is able to understand and comply with the study and has provided written informed consent.

Exclusion Criteria:

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Patients meeting any of the following criteria are not eligible for this trial:

1. Patients with a history of using immunosuppressive or hormonal drugs;
2. Patients receiving radiotherapy or chemotherapy;
3. Patients who fail to comply with our follow-up strategy;
4. Other situations that are not in conformity with the standards and requirements of this trial.

Where it's running

  • Jiang Wei
    Shanghai, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.