Exploring the link between carotid atherosclerosis and coronary artery disease
Carotid Atherosclerosis in Predicting Coronary Artery Disease
Shanghai Zhongshan Hospital · NCT06253962
This study looks at whether the buildup of plaque in the neck arteries is linked to heart artery disease in patients who have chest pain or tightness.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 14 Years to 90 Years |
| Sex | All |
| Sponsor | Shanghai Zhongshan Hospital (other) |
| Locations | 1 site (Shanghai) |
| Trial ID | NCT06253962 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the relationship between carotid atherosclerosis and coronary artery disease (CAD) by examining carotid plaque burden and composition features, particularly focusing on the lipid necrotic core. Patients experiencing chest tightness or pain will undergo carotid artery ultrasonography prior to coronary angiography to assess the correlation between carotid and coronary atherosclerosis. The study aims to identify phenotypic patterns of carotid atherosclerosis and their association with the prevalence and severity of CAD.
Who should consider this trial
Good fit: Ideal candidates for this study are patients experiencing chest tightness or chest pain who are scheduled for carotid ultrasound and coronary angiography.
Not a fit: Patients without symptoms of chest tightness or pain, or those not undergoing carotid ultrasound and coronary angiography, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of how carotid atherosclerosis predicts coronary artery disease, potentially leading to improved diagnostic and treatment strategies.
How similar studies have performed: While the specific approach of this study may be novel, previous studies have indicated a significant association between carotid atherosclerosis and coronary artery disease.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients receive carotid ultrasound and coronary angiography Exclusion Criteria: * None
Where this trial is running
Shanghai
- 180 Fenglin Road — Shanghai, China (RECRUITING)
Study contacts
- Study coordinator: Danbo Lu, PhD
- Email: lu.danbo@zs-hospital.sh.cn
- Phone: +86 021 64041990
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Carotid Atherosclerosis, Coronary Atheroscleroses