Exploring the link between carotid atherosclerosis and coronary artery disease
Official title: Carotid Atherosclerosis in Predicting Coronary Artery Disease
Run by Shanghai Zhongshan Hospital · NCT06253962 · Data updated 2026-11-12
This study looks at whether the buildup of plaque in the neck arteries is linked to heart artery disease in patients who have chest pain or tightness.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 14 Years to 90 Years |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Shanghai Zhongshan Hospital Academic / other |
| Locations | 1 site (Shanghai) |
| Status | Recruiting |
| Started | February 10, 2024 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2028 |
| Registry record updated | February 12, 2024 |
| Trial ID | NCT06253962 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients experiencing chest tightness or chest pain who are scheduled for carotid ultrasound and coronary angiography.
✕Probably not a fit
Patients without symptoms of chest tightness or pain, or those not undergoing carotid ultrasound and coronary angiography, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the relationship between carotid atherosclerosis and coronary artery disease (CAD) by examining carotid plaque burden and composition features, particularly focusing on the lipid necrotic core. Patients experiencing chest tightness or pain will undergo carotid artery ultrasonography prior to coronary angiography to assess the correlation between carotid and coronary atherosclerosis. The study aims to identify phenotypic patterns of carotid atherosclerosis and their association with the prevalence and severity of CAD.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of how carotid atherosclerosis predicts coronary artery disease, potentially leading to improved diagnostic and treatment strategies.
How similar studies have gone: While the specific approach of this study may be novel, previous studies have indicated a significant association between carotid atherosclerosis and coronary artery disease.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients receive carotid ultrasound and coronary angiography Exclusion Criteria: * None
Where it's running
-
180 Fenglin Road
Shanghai, China Recruiting
Study contacts
- Study coordinator: Danbo Lu, PhD
- Email: lu.danbo@zs-hospital.sh.cn
- Phone: +86 021 64041990
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Photon-counting CT vs conventional CT for carotid plaque in people with carotid artery stenosis
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.