Dihydroartemisinin for treating acne vulgaris

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults clinically diagnosed with acne vulgaris will take oral dihydroartemisinin daily for three months and return to the clinic once monthly for checkups and tests. The primary outcome is whether acne severity improves by at least one grade after treatment. Key exclusions include recent use of systemic or topical acne medications, pregnancy or breastfeeding, and serious heart, liver, kidney disease or malignancy. This is an early phase 1 interventional trial conducted at a single center to gather preliminary safety and efficacy signals.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Clinically diagnosed with acne vulgaris;
* For female patients, no pregnancy plans within the next 6 months.

Exclusion Criteria:

* Patients who have used sex hormones or other systemic medications for acne treatment within the past 3 months;
* Patients who have used topical medications for acne within the past 2 weeks;
* Pregnant or breastfeeding women;
* Patients with known severe diseases of vital organs (e.g., heart, liver, kidney) or malignancies.

Where it's running

• Zhongshan Hospital Fudan University
  Shanghai, Shanghai Municipality, China Recruiting

Study contacts

• Principal investigator: Jingjing JIANG, MD, PhD — Fudan University
• Study coordinator: Lujuan GAO, MD, PhD
• Email: gao.lujuan@zs-hospital.sh.cn
• Phone: 86-021-64041990

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.