Sponsor or institution
Clinical trials and research at Imperial College London
As of November 12, 2026, Find a Trial lists 92 clinical trials run by Imperial College London that are recruiting, at sites in 9 countries (most in United Kingdom (90), Ireland (2), Slovenia (1)). 1 was first registered in the last 30 days. By phase: Phase 3 (3), Phase 2 (3), Phase 1 (2), Early Phase 1 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 92Clinical trials
- 1New in 30 days
- 9Countries
Newest trials
All recruiting trials (92)
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REAL-MS: A Look at Autologous Stem Cell Transplant vs High-Efficacy MS Therapies in Real-World Care
This study tests how AHSCT compares to high-efficacy MS medicines in adults treated in routine clinical care.
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Factors Linked to Worsening or Improving Knee Osteoarthritis Over Time in Early Knee OA or Prior Acute Knee Injury
This observational study follows adults with early knee osteoarthritis or a prior knee injury to see if certain blood or knee-fluid markers, or genetic factors, can predict whether their knee condition will get worse or improve.
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Breath test to help detect gastrointestinal cancers early
A breath test that looks for signals in exhaled air to see if someone with gut cancer symptoms might have oesophageal, stomach, pancreatic, liver, or colorectal cancer and need urgent testing.
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Immune Responses to RSV in Older Adults After Nasal RSV Challenge
This study tests how the immune system responds to RSV in healthy adults aged 65–75 by giving them a controlled nasal infection in a monitored setting.
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EMG-Directed Virtual-Reality Training for Arm Rehab After Stroke or SCI
This study tests whether EMG-controlled virtual reality rehab can help improve arm and hand movement in people after stroke or spinal cord injury.
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Does a single dose of XBD173 change blood sugar in healthy adults?
A single dose of XBD173 is being tested in healthy adults to see if it affects fasting and after-glucose-drink blood sugar levels compared with a placebo.
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Observational look at antimicrobial resistance in people with chronic lung disease
This study tests how antimicrobial resistance appears in people with chronic lung diseases like COPD or bronchiectasis by collecting samples and health data over time.
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UK 22-Week Baby Observation: Learning What Happens for Infants Born at 22 Weeks
This study simply collects and shares de-identified medical notes about babies born at 22 weeks to see how they are cared for and what outcomes occur.
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Understanding how women feel about induction and how it shapes their experience
This study tests how prepared women feel about induction of labor and how that relates to their childbirth experience among those scheduled for induction at two London hospitals.
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Wearable MMG belt with haptics and games to motivate core exercises
This trial will test whether a wearable mechanomyography (MMG) biofeedback belt with a haptic-enabled mobile app and game features helps adults with chronic non-specific low back pain perform core exercises, reduce pain, and lower disability over 8 weeks.
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Comparing three specialist pacemakers to improve heart pumping and reduce rhythm problems
This study will test three types of specialist pacemakers in people with heart failure and reduced ejection fraction to see which best improves symptoms and heart rhythms over six months.
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Omnipod 5 system for insulin delivery in adults with type 2 diabetes on dialysis
This study tests whether an automated insulin delivery system (Omnipod 5) can help people with type 2 diabetes who are on haemodialysis control their blood sugar and feel better.
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Omicron SARS-CoV-2 challenge to study infection in vaccinated adults
This study tests a controlled Omicron variant in healthy adults who’ve had COVID-19 vaccines to see how it behaves and how the immune system responds.
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Lesion-specific angina thresholds measured during invasive coronary testing
This project tests whether different coronary narrowings cause angina at different levels of blood-flow reduction in people with stable angina who have two blockages suitable for PCI.
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Magic Angle Direction Imaging for ACL tears and meniscus injuries
This study tries a new low-field MRI technique called Magic Angle Direction Imaging to see if it shows ACL tears and meniscus injuries more clearly in adults scheduled for ligament repair.
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Breath test to detect pancreatic ductal adenocarcinoma (VAPOR2)
This research will try a non-invasive breath test that looks for volatile organic compounds to see if it can detect pancreatic cancer in adults referred from primary care with possible pancreatic symptoms.
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Household, wellbeing, and quality-of-life impacts of very preterm birth and necrotising enterocolitis
This project will collect information to see if pausing or continuing milk feeds around blood transfusions relates to babies' quality of life and the financial and emotional impact on families of very preterm infants, especially those with NEC.
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Multiomics analysis of how common colds cause COPD flare-ups
The team will intentionally infect people with moderate COPD and healthy volunteers with a common cold virus to see if detailed blood, lung, and genetic tests can find new targets to prevent or lessen COPD flare-ups.
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White matter damage and dementia markers in normal pressure hydrocephalus
This study tries to see if patterns of white matter damage, dementia-related biomarkers, wearable activity monitors, and digital cognitive tests can predict and track which older adults with normal pressure hydrocephalus will improve after CSF shunt surgery.
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AI analysis of ECGs to detect structural heart disease
This project will test whether AI can read traditional and wearable ECGs to find undiagnosed valve disease, pulmonary hypertension, and heart failure in adults.
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Personalised testing to find out if beta-blocker symptoms in heart failure are real or nocebo
This project will test a personalised sequence of low-dose bisoprolol, matched placebo, and no-pill weeks to see if people with HFrEF who stopped beta-blockers are experiencing true drug side effects or expected nocebo symptoms.
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Simplifying conduction system pacemaker implantation
This project will try new imaging and electrical mapping methods to make conduction system pacemakers easier to implant and interpret for adults who need ventricular pacing.
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Detecting hidden heart rhythm disorders using wearable ECG technology
This study is testing whether wearable heart monitors can help find hidden heart rhythm problems, specifically Brugada syndrome, in people who might not know they have it.
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Longitudinal study on cognitive health and Alzheimer's disease
This study is testing how changes in certain brain markers relate to memory and thinking skills in people over 65 to better understand Alzheimer's disease.
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Investigating how cold viruses affect bronchiectasis exacerbations
This study is trying to see if cold viruses make symptoms worse for people with bronchiectasis compared to healthy individuals.
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Assessing the impact of Chronic Pulmonary Aspergillosis on health and well-being
This study is trying to create a new questionnaire to help understand how Chronic Pulmonary Aspergillosis affects the daily lives of patients.
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A breath test to detect liver cancer and monitor liver health
This study is testing a new breath test to see if it can help find liver cancer earlier and keep track of liver health in adults with liver issues or certain stomach symptoms.
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Low‑dose psilocybin plus mental imagery therapy for young people who self-harm
This project tests whether a single low dose of psilocybin combined with a mental imagery technique can reduce self-harm urges in 16–25-year-olds who have recent self-harm and self-harm imagery.
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Using ultrasound to prevent insulin-related fatty lumps in people with diabetes
This project will try using ultrasound scans in diabetes clinics to find hidden insulin-related fatty lumps (lipohypertrophy) in adults on insulin who use CGM and have variable glucose levels.
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Breath test for detecting gastrointestinal cancers
This study is testing whether a simple breath test can help find gastrointestinal cancers early in people who might have them.
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Understanding how low oxygen levels affect oesophagogastric cancer
This study is testing how low oxygen levels in tumors affect the behavior of oesophagogastric cancer in patients to find out if it can help improve treatment options.
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Investigating how blood vessel invasion affects cancer spread in colorectal cancer
This study is trying to see if cancer spreading through blood vessels makes colorectal cancer worse than if it spreads through lymph nodes by looking at tissue samples from patients who had surgery.
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Improving brain blood flow in patients with cerebral small vessel disease
This study is testing if a new drug can improve blood flow in the brains of people with cerebral small vessel disease.
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How viral infections affect people with chronic lung disease
This study will test if respiratory viruses trigger flare-ups and change immune responses in adults with COPD or bronchiectasis.
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Comparing immune responses to influenza vaccination and infection in healthy adults
This study tests how healthy adults respond to the flu vaccine and a flu virus to see which one helps their immune system better.
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DE-iPTV radiotherapy for breast cancer that has spread to the brain in patients not eligible for SRS
This trial tests a dose-escalated internal PTV radiotherapy approach (DE-iPTV) for adults with breast cancer brain metastases who can’t have stereotactic radiotherapy, to see if it can be delivered safely and whether it improves quality of life.
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Remote monitoring for patients after heart valve replacement
This study tests if using remote monitoring can help patients who have had heart valve replacement recover better and go home sooner by catching any problems early.
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Comparing early and late blood glucose monitoring in pregnant women with a history of gestational diabetes
This study tests if pregnant women with a history of gestational diabetes do better when they monitor their blood sugar early in pregnancy instead of waiting until later.
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Automated insulin delivery for adults with advanced kidney disease.
This tries an automated insulin delivery system (Medtronic 780G) with continuous glucose monitoring in adults with type 1 or insulin-treated type 2 diabetes and advanced kidney disease to see if it improves glucose control and quality of life.
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Analyzing shopping habits to improve early cancer diagnosis
This study is trying to see if changes in shopping habits can help spot cancer earlier by looking at purchase data from loyalty cards of people recently diagnosed with cancer and those without it.
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Evaluating antibiotic effectiveness in patients with infections
This study is testing how well beta-lactam antibiotics work for patients with infections by checking if they get the right amount of the medicine in their system to help them recover.
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Ablation of focal activation in atrial fibrillation
This study is testing a new method to find specific electrical signals that may be causing ongoing atrial fibrillation in patients, to see if targeting these signals can improve their treatment.
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Investigating the effects of balloon occlusion on angina in patients with multi-vessel coronary artery disease
This study is testing how different blockages in the heart's arteries affect chest pain in people with multiple artery problems.
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Monitoring dietary intake using wearable biomarkers
This study is testing if wearable devices can help us better understand what and how much people eat by tracking their body's reactions during meals.
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Restoring gut bacteria before stem cell transplant for blood cancer patients
This study is testing if restoring gut bacteria with a special treatment before stem cell transplants can help blood cancer patients have better health and treatment outcomes.
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How GLP-1 analogues prevent steroid-induced diabetes
This study is testing if a new type of diabetes medication can help prevent high blood sugar caused by steroid treatment in people at risk for diabetes.
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Assessing biomarkers after surgery for oesophagogastric cancer
This study is trying to find out if certain biological markers in patients who had surgery for oesophageal and gastric cancer can help predict how well they will respond to treatment and their chances of recovery.
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Understanding the role of ATP and P2X3 receptors in chronic cough
This study is trying to understand what causes chronic cough by looking at lung inflammation and a specific molecule in people with the cough compared to healthy individuals.
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Using MRI scans to improve prostate cancer monitoring
This study is testing if regular MRI scans can help men with low to medium risk prostate cancer on active surveillance better monitor their condition compared to the usual PSA tests and exams.
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Breath test for detecting oesophageal cancer
This study is testing a breath test to see if it can help find oesophageal cancer early in people who have vague symptoms.
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Evaluating the use of compression stockings for patients needing blood-thinning medication after surgery
This study is testing if wearing compression stockings can help high-risk surgical patients who are on blood-thinning medication avoid dangerous blood clots.
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Public survey on breath testing for health and disease detection
This study is trying to see how people feel about using breath tests to check for health issues, including cancer, and what might make them more or less likely to use these tests.
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AI-guided cardiac MRI for automatic heart image positioning
This project will test an artificial intelligence tool that automatically positions heart images during cardiac MRI for adults having clinical scans to try to make scans faster and more consistent.
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Upgrading Pacemakers for Better Heart Function
This study tests if upgrading from a traditional pacemaker to a newer type can help people with heart problems feel better and improve their quality of life.
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Whole-body cooling for babies with mild neonatal encephalopathy
This trial will test whether lowering body temperature soon after birth helps newborns with mild hypoxic‑ischaemic encephalopathy have better development by age two.
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A digital tool for assessing cognitive impairment in stroke survivors
This study is testing a new digital tool that helps stroke survivors check for thinking and memory problems on their own to improve their care after a stroke.
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Breath test for early detection of colorectal cancer
This study is testing a breath test to see if it can help find colorectal cancer earlier in people who have symptoms or already know they have the disease.
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Understanding how heart conditions affect tolerance to rapid heart rates
This study is testing how well people with heart conditions, especially those with coronary artery disease, can handle fast heart rates and whether treating their condition with stents can help them tolerate it better.
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Comparing two pacing methods for treating slow heart rates
This study is testing two different ways to help people with slow heart rates feel better by comparing traditional pacing to a newer method in 2600 patients.
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Observing the causes and progression of cardiomyopathy
This study is trying to understand what causes cardiomyopathy and how it gets worse by collecting DNA, blood samples, and health information from people with the condition or those at risk.
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Preventing blood clots in patients undergoing varicose vein treatment
This study tests different blood-thinning medications to see which one best helps prevent blood clots in adults getting treatment for varicose veins.
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Breath test for early detection of pancreatic cancer
This study is testing a new breath test to see if it can help find pancreatic cancer earlier in patients.
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Evaluating MRI and biopsy methods for prostate cancer detection
This study is testing whether a new type of MRI and a different way to do biopsies can help find prostate cancer more accurately in men who might have it.
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Ablation of nerve endings in the right atrium for treating atrial fibrillation
This study is testing a new procedure that targets nerve endings in the right side of the heart to help people with persistent atrial fibrillation who haven't found relief from standard treatments.
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Non-invasive breath test for early detection of oesophageal and gastric cancer
This study is testing a new breath test to see if it can help find oesophageal and stomach cancers early in people who have symptoms.
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Understanding why some patients don't lose weight after bariatric surgery
This study is trying to find out why some people don’t lose as much weight as expected after bariatric surgery, focusing on the role of gut hormones to help improve their results.
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Erythropoietin treatment for newborns with encephalopathy in low and middle-income countries
This study is testing whether Erythropoietin can help improve the health of newborns with brain issues shortly after birth in low and middle-income countries.
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Combining ASTX727 with Lutathera for Neuroendocrine Tumors
This study is testing whether taking ASTX727 for five days before Lutathera treatment can help people with metastatic neuroendocrine tumors by looking at changes in a specific receptor.
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Research on inherited heart conditions in children
This study is trying to learn more about inherited heart conditions in children and their parents by collecting health information over five years to improve understanding and treatment.
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Reduced frequency of pembrolizumab treatment for advanced lung cancer
This study is testing if giving pembrolizumab treatment for advanced lung cancer less often can still work well while making life easier for patients.
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Evaluating how high doses of prednisolone affect patients with inflammatory conditions
This study is trying to see how different doses of prednisolone affect patients with inflammatory conditions by looking at their blood levels and how their bodies process the medication.
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Registry for patients with cardiomyopathy and myocarditis
This study is trying to gather health information from people with cardiomyopathy or myocarditis to better understand these conditions and their genetics.
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Early diagnosis of upper digestive tract diseases using breath tests
This study is testing a breath test to see if it can help find upper digestive tract cancers earlier in patients who are already getting checked for digestive issues.
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Using diabetes medications after bariatric surgery
This study is testing if continuing diabetes medications after bariatric surgery can help people with obesity and type 2 diabetes better manage their condition in the long run.
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Testing a new HIV treatment using antibodies
This study is testing whether a new treatment using special antibodies can help people recently diagnosed with HIV stay healthy after stopping their regular medication.
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Global collaboration to improve diagnosis and treatment of familial hypercholesterolemia
This study is trying to find better ways to diagnose and treat familial hypercholesterolemia, a genetic condition that causes high cholesterol and increases heart disease risk, by working with experts from around the world.
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Improving MRI accuracy for early-stage rectal cancer treatment
This study tests a new way for doctors to read MRIs to see if it can help more people with early-stage rectal cancer avoid major surgery and keep their bowel function.
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Real-time continuous glucose monitoring for young adults at risk of DKA
This project will try a Dexcom G6 real-time continuous glucose monitor to see if it helps 18-25-year-olds with insulin-treated diabetes who have poor blood sugar control or recent hospital admissions for high blood sugar.
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Understanding Androgen Excess and Metabolic Issues in Women with PCOS
This study is trying to find out how to predict metabolic problems in women with PCOS by looking at their health data and grouping them based on similar traits.
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Investigating who benefits from bariatric surgery for diabetes
This study is trying to find out which people with type 2 diabetes or prediabetes will benefit the most from bariatric surgery, specifically the Roux-en-Y gastric bypass.
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Novel PET imaging for HER2 in breast cancer
This study is testing a new imaging agent to see if it can better target HER2 in patients with metastatic breast cancer and help doctors understand how it works in different types of tumors.
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Improving diagnosis of rectal cancer using imaging techniques
This study is testing whether using advanced MRI techniques can help doctors better identify rectal cancer before surgery to improve treatment outcomes for patients.
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Cohort study on COPD exacerbations in London
This study looks at what causes flare-ups in people with COPD to help understand how the disease affects their health.
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Using MRI to assess tumor response in rectal cancer
This study is testing if using MRI scans to see how well rectal cancer is responding to treatment can help some patients avoid surgery and make better treatment choices.
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Examining blood samples in colorectal cancer patients to understand tumor spread
This study is testing if blood samples can help doctors understand how tumor spread relates to certain imaging features in patients with colorectal cancer who are about to have surgery.
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Improving treatment planning for recurrent colorectal cancer using MRI
This study is testing a new way to use MRI scans to help doctors plan better treatments for patients with recurrent colorectal cancer.
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Screening for liver metastases in high-risk colorectal cancer patients using MRI
This study is testing if a special type of MRI can find liver cancer spread earlier in patients with high-risk colorectal cancer compared to regular CT scans.
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Using MRI to Improve Treatment for Sigmoid Colon Cancer
This study is testing if using MRI scans can help doctors plan better treatments for patients with sigmoid colon cancer compared to regular CT scans.
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Effects of Kisspeptin on Reproductive Hormones
This study is testing if giving kisspeptin can change hormone levels in people with fertility issues or problems with their hypothalamus.
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Investigating gut hormones after gastric bypass surgery
This study is testing how certain gut hormones change after gastric bypass surgery to see if they help with weight loss and managing blood sugar in people with obesity and type 2 diabetes.
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Review of medical records for patients with hereditary bleeding disorders
This study looks at medical records of people with hereditary bleeding disorders to see if certain traits can help predict complications like strokes or pregnancy-related issues.
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Examining genes in families affected by hereditary hemorrhagic telangiectasia
This study is trying to find out which genes are linked to hereditary hemorrhagic telangiectasia by looking at the DNA of family members who have and don’t have the condition.
Quick answers
How many clinical trials run by Imperial College London are recruiting right now?
92, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 9 countries. The most sites are in United Kingdom (90 trials), Ireland (2 trials), Slovenia (1 trial), Italy (1 trial), Bangladesh (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 3, Phase 2: 3, Phase 1: 2, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.