Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Using diabetes medications after bariatric surgery

Official title: Medication Following Bariatric Surgery for Type 2 Diabetes Mellitus

Run by Imperial College London · NCT04432025 · Data updated 2026-11-12

This study is testing if continuing diabetes medications after bariatric surgery can help people with obesity and type 2 diabetes better manage their condition in the long run.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment150 (estimated)
SponsorImperial College London
Academic / other
Locations1 site (Dublin)
StatusRecruiting
StartedApril 1, 2021
Main results expectedApril 1, 2027
Study endsAugust 1, 2027
Registry record updatedAugust 8, 2022
Trial IDNCT04432025 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals eligible for bariatric surgery with a BMI greater than 30 and a diagnosis of type 2 diabetes.

Probably not a fit

Patients who have had previous bariatric surgery or those with contraindications to the procedure may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of continuing standard diabetes medications in patients who have undergone bariatric surgery. Traditionally, these medications are halted immediately after surgery, but this study aims to determine if ongoing use can enhance long-term diabetes control. By monitoring patients post-surgery, researchers will assess the safety and effectiveness of this approach in preventing relapse of diabetes symptoms. The study targets individuals with obesity and type 2 diabetes who meet specific eligibility criteria for bariatric surgery.

Why it matters

Potential benefit: If successful, this approach could lead to improved long-term management of type 2 diabetes in patients who undergo bariatric surgery.

How similar studies have gone: While the approach of continuing diabetes medications post-surgery is not widely tested, it addresses a significant gap in current treatment practices, suggesting potential for novel insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* eligible for bariatric surgery according to NICE guidelines (GC 189)
* Type 2 diabetes mellitus
* BMI \>30kg/m2

Exclusion Criteria:

* Recent hospitalisation in the past 30 days
* Recurrent hypoglycaemic episodes
* Recurrent hypotensive episodes
* Contraindications to bariatric surgery
* Previous bariatric surgery
* Current pregnancy
* Breastfeeding

Where it's running

  • University College Dublin
    Dublin, Ireland
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.