Using diabetes medications after bariatric surgery

Medication Following Bariatric Surgery for Type 2 Diabetes Mellitus

NA · Imperial College London · NCT04432025

This study is testing if continuing diabetes medications after bariatric surgery can help people with obesity and type 2 diabetes better manage their condition in the long run.

Quick facts

PhaseNA
Study typeInterventional
Enrollment150 (estimated)
Ages18 Years and up
SexAll
SponsorImperial College London (other)
Locations1 site (Dublin)
Trial IDNCT04432025 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of continuing standard diabetes medications in patients who have undergone bariatric surgery. Traditionally, these medications are halted immediately after surgery, but this study aims to determine if ongoing use can enhance long-term diabetes control. By monitoring patients post-surgery, researchers will assess the safety and effectiveness of this approach in preventing relapse of diabetes symptoms. The study targets individuals with obesity and type 2 diabetes who meet specific eligibility criteria for bariatric surgery.

Who should consider this trial

Good fit: Ideal candidates are individuals eligible for bariatric surgery with a BMI greater than 30 and a diagnosis of type 2 diabetes.

Not a fit: Patients who have had previous bariatric surgery or those with contraindications to the procedure may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved long-term management of type 2 diabetes in patients who undergo bariatric surgery.

How similar studies have performed: While the approach of continuing diabetes medications post-surgery is not widely tested, it addresses a significant gap in current treatment practices, suggesting potential for novel insights.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* eligible for bariatric surgery according to NICE guidelines (GC 189)
* Type 2 diabetes mellitus
* BMI \>30kg/m2

Exclusion Criteria:

* Recent hospitalisation in the past 30 days
* Recurrent hypoglycaemic episodes
* Recurrent hypotensive episodes
* Contraindications to bariatric surgery
* Previous bariatric surgery
* Current pregnancy
* Breastfeeding

Where this trial is running

Dublin

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Obesity, Type 2 Diabetes, obesity, type 2 diabetes

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.