A digital tool for assessing cognitive impairment in stroke survivors

Understanding Factors Affecting Cognitive Function in Cerebrovascular Disease

Observational Imperial College London · NCT05885295

This study is testing a new digital tool that helps stroke survivors check for thinking and memory problems on their own to improve their care after a stroke.

Quick facts

Study typeObservational
Enrollment700 (estimated)
Ages18 Years and up
SexAll
SponsorImperial College London Academic / other
Locations1 site (London)
Trial IDNCT05885295 on ClinicalTrials.gov

What this trial studies

This study aims to develop and validate the Imperial Comprehensive Cognitive Assessment in Cerebrovascular Disease (IC3), a self-administered digital tool designed to detect cognitive impairments in patients who have experienced a stroke. The IC3 will assess both general and specific cognitive deficits, allowing for scalable and cost-effective monitoring independent of trained professionals. The study will also explore the relationship between cognitive outcomes and various biomarkers, including MRI imaging and blood tests, over the first year following a stroke. By providing a comprehensive and standardized approach to cognitive assessment, the IC3 seeks to improve post-stroke care and monitoring.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 who have experienced a confirmed stroke and can engage in cognitive testing.

Not a fit: Patients with a pre-stroke diagnosis of dementia or severe cognitive impairments may not benefit from this study.

Why it matters

Potential benefit: If successful, this tool could significantly enhance the ability to identify and monitor cognitive deficits in stroke survivors, leading to better tailored rehabilitation strategies.

How similar studies have performed: While cognitive assessments post-stroke are common, the IC3 represents a novel approach that has not been extensively tested in this specific context.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aged \> 18
* Evidence of confirmed stroke (for patients)
* Ability to concentrate for 15 minutes at a time to engage with cognitive testing

Exclusion Criteria for the main study:

* Pre-stroke diagnosis of dementia
* Severe visuo-spatial problems, fatigue, or mental health problems
* Severe hearing impairment in the presence of reading comprehension impairment

Exclusion Criteria for the MRI imaging sub-study:

* Pregnancy
* Presence of metal implants
* Claustrophobia

Where this trial is running

London

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions StrokeStroke or TIADementia, VascularCerebrovascular DisordersSmall Vessel Cerebrovascular DiseaseCognitive ImpairmentdementiaMRI
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.