A digital tool for assessing cognitive impairment in stroke survivors
Official title: Understanding Factors Affecting Cognitive Function in Cerebrovascular Disease
Run by Imperial College London · NCT05885295 · Data updated 2026-11-12
This study is testing a new digital tool that helps stroke survivors check for thinking and memory problems on their own to improve their care after a stroke.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 700 (estimated) |
| Sponsor | Imperial College London Academic / other |
| Locations | 1 site (London) |
| Status | Recruiting |
| Started | December 1, 2021 |
| Main results expected | May 15, 2028 |
| Study ends | May 15, 2028 |
| Registry record updated | June 1, 2023 |
| Trial ID | NCT05885295 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 who have experienced a confirmed stroke and can engage in cognitive testing.
✕Probably not a fit
Patients with a pre-stroke diagnosis of dementia or severe cognitive impairments may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to develop and validate the Imperial Comprehensive Cognitive Assessment in Cerebrovascular Disease (IC3), a self-administered digital tool designed to detect cognitive impairments in patients who have experienced a stroke. The IC3 will assess both general and specific cognitive deficits, allowing for scalable and cost-effective monitoring independent of trained professionals. The study will also explore the relationship between cognitive outcomes and various biomarkers, including MRI imaging and blood tests, over the first year following a stroke. By providing a comprehensive and standardized approach to cognitive assessment, the IC3 seeks to improve post-stroke care and monitoring.
Why it matters
Potential benefit: If successful, this tool could significantly enhance the ability to identify and monitor cognitive deficits in stroke survivors, leading to better tailored rehabilitation strategies.
How similar studies have gone: While cognitive assessments post-stroke are common, the IC3 represents a novel approach that has not been extensively tested in this specific context.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged \> 18 * Evidence of confirmed stroke (for patients) * Ability to concentrate for 15 minutes at a time to engage with cognitive testing Exclusion Criteria for the main study: * Pre-stroke diagnosis of dementia * Severe visuo-spatial problems, fatigue, or mental health problems * Severe hearing impairment in the presence of reading comprehension impairment Exclusion Criteria for the MRI imaging sub-study: * Pregnancy * Presence of metal implants * Claustrophobia
Where it's running
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Imperial College London
London, United Kingdom Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.