Assessing the impact of Chronic Pulmonary Aspergillosis on health and well-being
Official title: Impact of Chronic Pulmonary Aspergillosis (CPA) on Health Status and Well-being
Run by Imperial College London · NCT06885905 · Data updated 2026-11-12
This study is trying to create a new questionnaire to help understand how Chronic Pulmonary Aspergillosis affects the daily lives of patients.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Imperial College London Academic / other |
| Locations | 3 sites (Dundee and 2 other locations) |
| Status | Recruiting |
| Started | November 27, 2024 |
| Main results expected | August 23, 2025 |
| Study ends | April 23, 2026 |
| Registry record updated | March 20, 2025 |
| Trial ID | NCT06885905 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older who have been diagnosed with Chronic Pulmonary Aspergillosis and can provide informed consent.
✕Probably not a fit
Patients who do not speak or understand English may not benefit from this study due to the language requirements for participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to develop and validate a new questionnaire specifically designed to measure health-related quality of life (HRQoL) in patients suffering from Chronic Pulmonary Aspergillosis (CPA). By focusing on the unique challenges faced by these patients, the CPA-HAQ questionnaire will be utilized in clinical research and trials to better understand the disease's impact on daily living. The study will involve patients who meet specific eligibility criteria, including age and diagnosis, to ensure accurate data collection and analysis.
Why it matters
Potential benefit: If successful, this study could provide a valuable tool for assessing the quality of life in CPA patients, leading to improved patient care and treatment strategies.
How similar studies have gone: While this approach is focused on developing a specific questionnaire, similar studies have successfully validated disease-specific HRQoL measures in other conditions, indicating potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. All patients \>/= 18 years old and able to provide informed consent 2. Patients with a diagnosis of chronic pulmonary aspergillosis 3. To speak and understand English 4. Able to provide informed consent
Where it's running
-
Ninewells Hospital & Medical School
Dundee, United Kingdom Recruiting -
Imperial College London
London, United Kingdom Recruiting -
Manchester NHS Foundation Trust
Manchester, United Kingdom Recruiting
Study contacts
- Study coordinator: Dareen Marghlani, MSc
- Email: dsm20@ic.ac.uk
- Phone: dsm20@ic.ac.uk
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Comparing nebulized amphotericin B and saline for chronic pulmonary aspergillosis treatment
This study is testing if a nebulized form of amphotericin B can help people with chronic pulmonary aspergillosis feel better compared to using saline after they've already been treated with oral itraconazole.
-
Comparing oral itraconazole alone versus with glucocorticoids for lung disease overlap
This study tests whether taking oral itraconazole alone or with glucocorticoids helps people with both Chronic Pulmonary Aspergillosis and Allergic Bronchopulmonary Aspergillosis feel better.
-
Comparing two treatments for Chronic Pulmonary Aspergillosis
This study is testing if a combination of two treatments can help people with Chronic Pulmonary Aspergillosis feel better compared to using just one of the treatments alone.
-
PCR testing in blood and lung washings to monitor invasive pulmonary aspergillosis
This will test whether repeated PCR tests for Aspergillus fumigatus in blood and bronchoalveolar lavage fluid can track treatment response in adults with invasive pulmonary aspergillosis.
-
Breath analysis to detect fungal infections in leukemia patients
This study is testing if analyzing breath samples can help doctors detect fungal infections in leukemia patients who are at high risk due to their treatment.
-
Early diagnosis of invasive lung aspergillosis
This study is trying to see if new tests can help doctors diagnose lung infections caused by fungus earlier in critically ill patients.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.