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Clinical trials and research at Children's Hospital Medical Center, Cincinnati

• 113Clinical trials
• 9Countries

Newest trials

All recruiting trials (113)

• Allogeneic HCT for Refractory sJIA in Children and Young Adults

  This study tests whether donor blood-forming cell transplantation can help children and young adults with difficult-to-treat systemic JIA, including those with lung involvement.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07845942

• Proton MRI of Musculoskeletal and Lung Health

  This study tests MRI techniques to take clearer pictures of the lungs in healthy people and those with lung, muscle, or bone conditions.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07845708

• See how well the lungs distribute dissolved xenon gas during MRI in HSCT patients and others

  This study tests a special MRI method using hyperpolarized xenon gas to visualize how gas and dissolved xenon move through the lungs in people who have HSCT, respiratory issues, or are healthy controls.

  Recruiting Phase 1/2 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07823036

• Semaglutide for teens with autism and obesity

  This 6-month, two-arm study tests whether semaglutide can help reduce BMI in adolescents 12-18 with autism and obesity, alongside lifestyle counseling.

  Recruiting Phase 4 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07770152

• FST Decision Support to Help Timely Therapy for Kids with AKI Risk

  This study tests whether adding a clinical decision support tool to the electronic medical record helps clinicians use the furosemide stress test in critically ill children at high risk for severe AKI.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07718464

• Optimizing Hydroxyurea in Children with Sickle Cell in Africa

  This study tests whether raising hydroxyurea to a maximum tolerated dose is safe and beneficial for Ugandan children with sickle cell anemia already taking a fixed daily dose.

  Recruiting Phase 1/2 Children's Hospital Medical Center, Cincinnati · Kampala · NCT07708714

• Impact of Sleep Timing and Duration on Teens with ADHD

  This study tests how changing how long and when teens with ADHD sleep affects their attention and daily functioning.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07684417

• Understanding Genetic Causes of Congenital Hemolytic Anemias

  Researchers are testing if certain genetic mutations cause non-immune hemolytic anemia in patients with inherited blood disorders.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07649213

• Sleep and Teens’ Immune Response to a Meningococcal Vaccine

  This study checks if 11- to 12-year-olds’ sleep habits affect how well their vaccine for meningococcal disease works.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07636525

• CIML-NK Cells to Treat Neuroblastoma in Relapsed or Refractory Patients

  We’re testing whether donor-derived cytokine-induced memory-like NK cells can be safely given with dinutuximab to kids and young adults whose neuroblastoma has come back or not responded to treatment.

  Recruiting Phase 2 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07635056

• Quercetin for Dyskeratosis Congenita and Telomere Biology Disorders

  This pilot study tests whether quercetin is safe to use in people with DC or telomere biology disorders.

  Recruiting Phase 1 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07628972

• Understanding subtypes of chronic musculoskeletal pain in youth

  This observational study tests whether distinct brain and immune profiles can explain chronic musculoskeletal pain in teens and young adults to guide more precise treatments.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07602595

• Heart Institute Biorepository for children with heart disease

  This project collects and stores blood, tissue, and other samples from people with pediatric heart disease so researchers can use them to learn more and develop new tests and treatments.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07478354

• Heart Institute Biobank and Registry for Adults with Congenital Heart Disease and Related Conditions

  This project will collect blood, tissue samples, and detailed health information from adults (≥16) with congenital heart disease and related heart or vascular conditions to create a resource researchers can use.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07477197

• Quality of Life in Children and Young People with HHT

  This study looks at how HHT affects daily life for kids and young adults ages 2 to 25 and asks caregivers and patients to fill out quality-of-life surveys.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07474428

• Quercetin for males with XIAP deficiency

  This trial will test whether taking quercetin by mouth safely lowers inflammation in males with XIAP deficiency.

  Recruiting Phase 1 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07433621

• Exercise to lower blood fats and improve blood-vessel health in young people with obesity

  This study will test whether adding a structured exercise program to the Healthworks! weight-loss program helps lower blood fat levels and improve blood-vessel function in 10–20-year-olds with obesity.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07409064

• Early zoledronate to prevent bone problems after pediatric stem cell transplant

  This pilot tests whether giving zoledronate early can prevent bone loss and fractures in children and teens undergoing or recovering from hematopoietic stem cell transplant who are at high risk.

  Recruiting Phase 1 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07375290

• Checking measles vaccine response in children with sickle cell disease

  This study tests whether infants and young children with sickle cell disease develop enough protection in the weeks after their measles vaccine.

  Recruiting at 3 sites Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio and 2 other locations · NCT07356050

• Measuring brain network activity to predict and improve outcomes in children with dystonia

  This project will test whether noninvasive brain and muscle recordings, and comparing DBS on versus off, can predict and help improve motor outcomes for children with dystonia.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07325175

• Survivors Journey+: an online family program for teen and young adult brain tumor survivors

  This project will test whether the Survivors Journey+ online program with weekly coaching helps teen and young adult pediatric brain tumor survivors (ages 15–25) and their caregivers manage everyday challenges better than an information-only website.

  Recruiting at 2 sites Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio and 1 other locations · NCT07321353

• Treating ADHD in preschoolers: methylphenidate vs guanfacine

  This study tests whether methylphenidate or guanfacine works better for kids ages 3–5 with ADHD.

  Recruiting at 5 sites Phase 4 Children's Hospital Medical Center, Cincinnati · Palo Alto, California and 4 other locations · NCT07300956

• Preventing graft rejection after allogeneic stem cell transplant

  This trial will try the drug emapalumab to see if it can prevent graft rejection in people judged high risk after allogeneic hematopoietic stem cell transplant.

  Recruiting Early Phase 1 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07244419

• Tailored program to help teens and young adults with cancer take their meds

  A tailored program is being tested to see if it helps adolescents and young adults with cancer take their oral medications more consistently than the standard approach.

  Recruiting at 2 sites Children's Hospital Medical Center, Cincinnati · Kansas City, Kansas and 3 other locations · NCT07223463

• Deep TMS for adolescents hospitalized with depression

  This trial will try deep transcranial magnetic stimulation (dTMS) as an add-on to usual care for 14–18-year-olds hospitalized with major depressive disorder to see if it reduces depressive symptoms, suicidal thoughts, and readmissions.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07217444

• Amino acid infusion after heart surgery to protect kids’ kidneys

  This study tests whether giving an amino acid infusion during and after pediatric heart surgery can lower the chance of acute kidney injury and reduce time on a ventilator, compared with a placebo.

  Recruiting Phase 2 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07212595

• SMART-IBD app for teens with inflammatory bowel disease

  This will test whether the SMART-IBD smartphone app helps adolescents ages 13–17 with IBD take their medicines and manage symptoms better than completing daily diaries alone.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07195123

• Fetal tracheal occlusion (FETO) for severe congenital diaphragmatic hernia

  This trial will test whether fetal endoluminal tracheal occlusion (FETO) helps fetuses with severe congenital diaphragmatic hernia and intrathoracic liver herniation survive to hospital discharge.

  Recruiting Phase 3 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07187206

• Personalized hydroxyurea dosing using blood-level guidance for children with sickle cell anemia (ENHANCE)

  This trial will test whether starting hydroxyurea based on how each child absorbs the drug (a PK-guided dose) helps babies and children with sickle cell anemia get higher fetal hemoglobin and better organ protection over time.

  Recruiting Phase 4 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07177300

• Stop penicillin in children with mild rheumatic heart disease to see if it’s still safe

  This study tests whether stopping secondary antibiotic prophylaxis is no worse than continuing it for 2 years in kids and teens with mild rheumatic heart disease who have already been treated.

  Recruiting Phase 3 Children's Hospital Medical Center, Cincinnati · Kampala, UG · NCT07146048

• Tracking growth, puberty, fertility, and pregnancy in people with sickle cell anemia

  This study will see if taking hydroxyurea changes growth, puberty, fertility, or pregnancy outcomes in people with sickle cell anemia.

  Recruiting at 3 sites Children's Hospital Medical Center, Cincinnati · Santo Domingo and 2 other locations · NCT07116772

• 18F-FAPI-74 PET imaging for lung fibrosis in tuberculosis

  This project tries to see if 18F-FAPI-74 PET scans can detect lung fibrosis in adults with active or recently treated tuberculosis.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07077213

• Helping Head Start preschoolers at risk connect with mental health services.

  This project will try family navigation plus a web dashboard to see if they help caregivers of Head Start preschoolers (ages 3–5) at risk for mental health disorders get mental health support sooner.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07054554

• Romiplostim to prevent chemotherapy-related low platelets in Ewing sarcoma

  This trial will test whether giving romiplostim during interval-compressed chemotherapy can reduce episodes of low platelets in people with newly diagnosed Ewing sarcoma.

  Recruiting at 2 sites Early Phase 1 Children's Hospital Medical Center, Cincinnati · Phoenix, Arizona and 1 other locations · NCT07048249

• Liraglutide for people with maturity-onset diabetes of the young (MODY)

  This trial will try liraglutide in people with genetically confirmed MODY to see if it improves blood sugar, body weight, and gastrointestinal symptoms.

  Recruiting Phase 2 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07029009

• Surgery to improve outcomes in Twin-Twin Transfusion Syndrome

  This study is testing if closing the hole in the amniotic membrane during surgery for Twin-Twin Transfusion Syndrome can lead to healthier pregnancies and better delivery outcomes.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT06991400

• Virtual reality and simulator training to reduce distracted driving in teens with ADHD

  This program will test two training approaches—one using virtual reality and one using a driving simulator—to help licensed teens with ADHD keep their eyes on the road and reduce crash risk.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT06960980

• Evaluation of the Autism Doula Program for Black families with autism

  This study is testing a support program for Black families with children recently diagnosed with autism to see if it helps them feel more satisfied and less stressed compared to regular care.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT06896942

• Inotuzumab Ozogamicin + Venetoclax + Dexamethasone (IoVeX) for relapsed B-cell ALL

  This trial will test whether the drug combination Inotuzumab Ozogamicin, Venetoclax, and Dexamethasone (IoVeX) is safe and well tolerated in children and adults with relapsed B-cell acute lymphoblastic leukemia.

  Recruiting Phase 1 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT06863259

• Intervention for parents of very preterm children to improve behavior

  This study is testing two different parenting programs to see if they can help parents of very preterm children improve their parenting skills and reduce behavior problems in their kids.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT06767293

• Comparing white dental crowns to metal crowns for children's teeth

  This study tests if a new flexible white dental crown works just as well as the traditional metal crown for young children needing dental work.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT06713330

• Improving social and academic skills in middle-schoolers with autism

  This study tests two different group programs to see if they can help middle-school kids with autism improve their social and school skills.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT06705907

• Comparing pain management methods after pectus surgery

  This study is testing whether using an ES catheter or cryoablation helps people recovering from pectus surgery manage their pain better and reach their physical therapy goals.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT06682208

• Comparing oxygen delivery methods for children with obstructive sleep apnea

  This study is testing whether two different ways of delivering oxygen can help children with Down syndrome who have moderate to severe obstructive sleep apnea breathe better during sleep.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT06609694

• Improving executive functioning in teens with epilepsy through a web-based intervention

  This study is testing a new online program to see if it can help teenagers with epilepsy improve their thinking skills and overall quality of life.

  Recruiting at 3 sites Children's Hospital Medical Center, Cincinnati · Orange, California and 2 other locations · NCT06608966

• Understanding sound perception in infants with Fragile X Syndrome

  This study tests how infants and toddlers with Fragile X Syndrome hear and understand sounds compared to other children to help identify early signs of language delays.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT06560242

• Telehealth intervention for autistic adolescents focusing on daily living skills

  This study is testing if a telehealth program can help autistic teens improve their daily living skills better than a social skills program as they prepare for adulthood.

  Recruiting at 2 sites Children's Hospital Medical Center, Cincinnati · Carrboro, North Carolina and 1 other locations · NCT06552286

• Comparing abbreviated MRI for Crohn's disease

  This study is testing a quicker MRI method using glucagon and water to see if it can effectively show inflammation in the small bowel for both kids and adults with Crohn's Disease.

  Recruiting at 2 sites Children's Hospital Medical Center, Cincinnati · Rochester, Minnesota and 1 other locations · NCT06533228

• Single high-dose vitamin A given with allogeneic stem cell transplant

  This study tests whether giving one large oral dose of vitamin A to adults having an allogeneic stem cell transplant can lower the chance of moderate-to-severe chronic graft-versus-host disease.

  Recruiting at 3 sites Phase 2 Children's Hospital Medical Center, Cincinnati · Tampa, Florida and 2 other locations · NCT06450925

• Monitoring lung changes in cystic fibrosis patients

  This study is testing new ways to see how stopping and starting airway clearance therapy affects lung health in people with cystic fibrosis.

  Recruiting Early Phase 1 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT06339593

• Therapy using brain stimulation for children with ADHD

  This study is testing whether a special brain stimulation treatment can help children with ADHD improve their ability to control their impulses.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT06325813

• Mapping the prevalence of sickle cell disease in Uganda

  This study is trying to find out how common sickle cell trait and sickle cell disease are in Uganda by testing blood samples from infants to help improve health strategies for these conditions.

  Recruiting at 4 sites Children's Hospital Medical Center, Cincinnati · Kampala and 3 other locations · NCT06301893

• Improving self-management in adolescents with sickle cell disease

  This study is testing a new online program to help teenagers and young adults with sickle cell disease better manage their health and see if it works better than regular care.

  Recruiting Children's Hospital Medical Center, Cincinnati · Wilmington, Delaware and 3 other locations · NCT06290401

• Using sound to improve cognitive function and sensory sensitivity in youth with developmental disorders

  This study is testing if listening to special sounds can help improve thinking skills and reduce sensitivity to noise in children with Fragile X Syndrome and Autism Spectrum Disorder.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT06227780

• HeartGPS: Prenatal psychological support for parents and babies after a single ventricle heart diagnosis

  This study tests whether an eight-session prenatal psychological program (HeartGPS) for parents of fetuses with single ventricle congenital heart disease can reduce parent distress and support fetal and infant brain and developmental outcomes.

  Recruiting Children's Hospital Medical Center, Cincinnati · Los Angeles, California and 3 other locations · NCT06175104

• Registry for pregnant women with Tuberous Sclerosis Complex and Lymphangioleiomyomatosis

  This study is collecting information from pregnant women with Tuberous Sclerosis Complex and Lymphangioleiomyomatosis to see how their health and their babies' health are affected during pregnancy.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT06160310

• Feasibility of a digital asthma management platform for children

  This study is testing a new app designed to help kids with asthma, aged 11-17, manage their condition better by tracking their symptoms and connecting with their doctors.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT06159127

• Treatment with mirdametinib for histiocytic disorders

  This study is testing a new treatment called mirdametinib to see if it helps people with Langerhans cell histiocytosis and other histiocytic disorders feel better with fewer side effects than current options.

  Recruiting Phase 2 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT06153173

• Effects of soy milk on liver health in children with fatty liver disease

  This study is testing if drinking soy milk every day can help improve liver health in children with fatty liver disease compared to regular cow's milk.

  Recruiting Phase 2 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT06133101

• Study of crushed venetoclax tablets dissolved in liquid for pediatric patients

  This study tests if crushing venetoclax tablets and mixing them with liquid helps children with blood cancers absorb the medication better and stay safe while taking it.

  Recruiting at 5 sites Children's Hospital Medical Center, Cincinnati · Aurora, Colorado and 5 other locations · NCT06131801

• Remote intervention for emotional regulation in children with Tuberous Sclerosis Complex

  This study is testing a remote program to help children with Tuberous Sclerosis Complex learn to manage their emotions better through group therapy and support for their caregivers.

  Recruiting Children's Hospital Medical Center, Cincinnati · Carrboro, North Carolina and 1 other locations · NCT06105736

• Obesity prevention program for high-risk infants

  This study is testing a parenting program to help prevent obesity in infants from low-income or minority communities during regular doctor visits.

  Recruiting Phase 2 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT06028113

• Improving HIV Screening and Prevention for Adolescents in Emergency Departments

  This study is trying out a new way to offer HIV testing and prevention services to teens aged 15-21 in emergency rooms to help keep them safe from HIV.

  Recruiting Children's Hospital Medical Center, Cincinnati · Columbus, Ohio and 3 other locations · NCT06003192

• Understanding sound perception in preschoolers with Fragile X Syndrome

  This study is trying to see how preschoolers with Fragile X Syndrome hear and understand sounds and language compared to other kids, to help identify early signs of speech and language challenges.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT05957549

• Comparing telehealth cognitive behavioral therapy for youth with migraines

  This study is testing whether online therapy for kids and teens with migraines works better when combined with medication or on its own.

  Recruiting at 15 sites Children's Hospital Medical Center, Cincinnati · Birmingham, Alabama and 14 other locations · NCT05889624

• Understanding how the brain processes chronic pain in children

  This study is trying to understand how children's brains handle chronic pain from conditions like migraines and fibromyalgia to see what helps them recover.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT05814497

• Using dogs to help children with autism manage emotions

  This study tests whether including dogs in a treatment program can help children with autism manage their emotions better.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT05803343

• Program to prevent rheumatic heart disease in Northern Uganda

  This study is testing a new program in Northern Uganda to see if it can effectively prevent Rheumatic Heart Disease in children and young adults through community screenings and local health services.

  Recruiting Children's Hospital Medical Center, Cincinnati · Kampala, Uganda · NCT05783375

• New cell transplantation therapy for hereditary lung disease

  This study is testing a new cell therapy for people with hereditary lung disease to see if it can improve lung function and help clear out harmful substances in the lungs.

  Recruiting Phase 1/2 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT05761899

• Understanding pain processing in adolescents with chronic pain conditions

  This study looks at how teenagers with ongoing pain conditions feel and process pain differently than those with specific pain or healthy teens to better understand what might cause their pain.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT05752396

• Improving outcomes in pediatric autoimmune liver disease

  This study is trying to improve care for kids with autoimmune liver diseases by collecting and sharing information about their treatments and health to help doctors provide better support.

  Recruiting at 8 sites Children's Hospital Medical Center, Cincinnati · Palo Alto, California and 7 other locations · NCT05750498

• Personalized infliximab dosing for Crohn's disease treatment

  This study is testing whether a computer program that customizes infliximab doses based on blood tests can help people with Crohn's disease feel better compared to the usual dosing methods.

  Recruiting at 11 sites Phase 2/3 Children's Hospital Medical Center, Cincinnati · Los Angeles, California and 10 other locations · NCT05660746

• Road-to-Recovery: web support for families after a child's traumatic brain injury

  This project will try a web-based Road-to-Recovery program to help caregivers of children (3 months–18 years) recovering from complicated mild to severe traumatic brain injury, compared with usual medical care plus online resources.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT05622461

• Cytokine-Induced Memory-Like Natural Killer Cells for Acute Myeloid Leukemia

  This study is testing a new way to use special immune cells to help patients with hard-to-treat acute myeloid leukemia feel better when standard chemotherapy isn't an option for them.

  Recruiting Phase 1/2 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT05580601

• Observing the development of infants with cerebral palsy

  This study looks at how infants with or at risk for cerebral palsy grow and develop in their first two years to help doctors and therapists better support them.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT05576948

• Registry for patients with relapsed and refractory hepatoblastoma

  This study is trying to gather information from patients with relapsed or hard-to-treat hepatoblastoma to better understand the disease and improve treatment options.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT05556642

• Treatment of Lupus Nephritis in Children and Young Adults

  This study is testing two different ways of giving a medication to see which one works better for children and young adults with lupus nephritis.

  Recruiting at 19 sites Phase 2 Children's Hospital Medical Center, Cincinnati · San Francisco, California and 18 other locations · NCT05538208

• Adjusting Alemtuzumab Dosing for Bone Marrow Transplantation

  This study is testing if adjusting the dose of alemtuzumab can help kids and young adults getting a bone marrow transplant have fewer complications and recover better.

  Recruiting Phase 2 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT05501756

• Examining the effects of Zemaira in patients with Eosinophilic Esophagitis

  This study is testing if the medication Zemaira can help adults with eosinophilic esophagitis feel better after receiving weekly infusions for four weeks.

  Recruiting at 2 sites Phase 2 Children's Hospital Medical Center, Cincinnati · Bethesda, Maryland and 1 other locations · NCT05485155

• Evaluating blood pressure measurements in children and adolescents

  This study is testing if measuring blood pressure at home can help doctors better understand different blood pressure conditions in kids and teens who have high blood pressure.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT05297708

• Registry for patients with Hemophagocytic Lymphohistiocytosis

  This study is collecting information from patients with Hemophagocytic Lymphohistiocytosis to better understand the condition and improve future treatments.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT05277272

• Using dogs in therapy for children recovering from brain injuries

  This study is testing if having dogs in therapy helps children recovering from brain injuries feel more engaged and benefit more during their rehabilitation.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT05250180

• Examining gastric motility in patients with eosinophilic gastritis

  This study is trying to see if people with eosinophilic gastritis have problems with how their stomach moves and digests food.

  Recruiting at 3 sites Children's Hospital Medical Center, Cincinnati · Chicago, Illinois and 2 other locations · NCT05229432

• Hyperpolarized 129Xe MRI for lung imaging in infants

  This study tests a new type of MRI using a special gas to safely check the lungs of newborns in the NICU for common breathing problems.

  Recruiting Phase 4 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT04995562

• Improving surgical outcomes for children with obstructive sleep apnea using advanced imaging techniques

  This study is testing a new tool that uses advanced imaging to help doctors predict how well surgery will work for children with sleep apnea who haven't improved with other treatments.

  Recruiting Phase 4 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT04991389

• Using abatacept to treat lung disease in patients with common variable immunodeficiency

  This study is testing if a medication called abatacept can help people with common variable immunodeficiency and lung disease feel better.

  Recruiting at 6 sites Phase 2 Children's Hospital Medical Center, Cincinnati · San Francisco, California and 5 other locations · NCT04925375

• Motor intervention for infants at risk for cerebral palsy

  This study is testing a new program called 'Let's Move' to see if it can help infants at risk for cerebral palsy improve their motor skills through a mix of clinic visits and home therapy using video calls.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT04886895

• Investigating lung disease markers in cystic fibrosis and bronchiectasis patients

  This study is trying to see if special imaging techniques can help doctors understand how lung disease is getting worse in kids with cystic fibrosis and bronchiectasis, even if their breathing tests look normal.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT04793867

• Testing drug effectiveness for cystic fibrosis using personalized medicine

  This study is testing if personalized medicine can help find the best CF treatments for people with rare cystic fibrosis gene mutations by using their own nasal cells.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT04580368

• Testing brain function measures in children with ADHD

  This study is testing how a single dose of a common ADHD medication affects brain function in children with ADHD to help improve their treatment.

  Recruiting at 2 sites Phase 4 Children's Hospital Medical Center, Cincinnati · Baltimore, Maryland and 1 other locations · NCT04421248

• Collection of bio-specimens from patients with RASopathies

  This study is collecting samples from people with RASopathies to help researchers learn more about these rare genetic disorders and how they affect the body.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT04395495

• Using donor-derived T-cells to fight viral infections after stem cell transplant

  This study is testing whether using special immune cells from donors can help prevent or treat viral infections in people who have had a stem cell transplant.

  Recruiting Phase 2 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT04230356

• Using nitric oxide during heart surgery in newborns to prevent kidney injury

  This study is testing if using nitric oxide during heart surgery can help newborns avoid kidney injury after their operation.

  Recruiting Phase 3 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT04216927

• Long-term observation of lung injury in children after stem cell transplants

  This study looks at children who have had stem cell transplants to see how often they develop lung problems and how these issues affect their health over time.

  Recruiting at 9 sites Children's Hospital Medical Center, Cincinnati · San Francisco, California and 8 other locations · NCT04098445

• Understanding hydroxyurea effects during pregnancy and breastfeeding in women with sickle cell disease

  This study looks at how taking hydroxyurea during pregnancy and breastfeeding affects women with sickle cell disease and their babies to better understand the risks and outcomes.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT04093986

• Comparing outpatient crisis intervention to inpatient care for suicidal teens

  This study tests whether an outpatient crisis intervention program can help suicidal teens just as well as staying in the hospital.

  Recruiting at 3 sites Children's Hospital Medical Center, Cincinnati · Glen Oaks, New York and 3 other locations · NCT04089254

• Combining venetoclax with Vyxeos for young patients with relapsed or refractory acute leukemia

  This study is testing a new treatment combining venetoclax and Vyxeos to see if it helps young patients with relapsed or hard-to-treat acute leukemia feel better.

  Recruiting Phase 1 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT03826992

• Using MRI to study lung development in infants with Bronchopulmonary Dysplasia

  This study is testing how MRI scans can help us understand lung development in premature infants with Bronchopulmonary Dysplasia by comparing them to infants without the condition.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT03657693

• Using MRI to predict outcomes in children with autoimmune liver disease

  This study is testing if MRI scans can help predict how well children with autoimmune liver diseases will do over time.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT03178630

• Using MRI to assess liver damage in children with autoimmune liver disease

  This study is testing if MRI scans can safely show liver damage in children with autoimmune liver diseases like PSC and AIH, helping doctors understand their condition better without needing invasive tests.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT03175471

• Registry for patients with Diffuse Intrinsic Pontine Glioma and Diffuse Midline Glioma

  This study is creating a registry to collect information and tissue samples from patients with Diffuse Intrinsic Pontine Glioma and Diffuse Midline Glioma to help improve how these tumors are diagnosed and treated.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT03101813

• Identifying biomarkers for vascular anomalies

  This study is trying to find simple blood tests that can help doctors better diagnose and treat patients with rare blood vessel problems like Generalized Lymphatic Anomaly and Gorham-Stout Disease.

  Recruiting Children's Hospital Medical Center, Cincinnati · Boston, Massachusetts and 1 other locations · NCT03001180

• Fetal tracheal occlusion for severe congenital diaphragmatic hernia

  This study is testing if a procedure called fetal tracheal occlusion can help improve lung development in unborn babies with severe congenital diaphragmatic hernia.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT02986087

• Registry for patients with Congenital Dyserythropoietic Anemia

  This study is collecting information from people with Congenital Dyserythropoietic Anemia to help researchers learn more about the condition and improve care for those affected.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT02964494

• Improving care for infants with complex heart conditions

  This study is trying to improve the care and outcomes for infants with Hypoplastic Left Heart Syndrome by collecting important health information and involving parents in their treatment.

  Recruiting at 59 sites Children's Hospital Medical Center, Cincinnati · Birmingham, Alabama and 62 other locations · NCT02852031

• Infusion of donor-derived T-cells for viral infections in immunocompromised patients

  This study is testing whether T-cells from donors can help children with weakened immune systems fight off viral infections like EBV, CMV, and ADV after they have had stem cell transplants.

  Recruiting at 3 sites Phase 2 Children's Hospital Medical Center, Cincinnati · Akron, Ohio and 3 other locations · NCT02532452

• Evaluating outcomes in eosinophilic gastrointestinal disorders

  This study is trying to find the best ways to measure how well people with eosinophilic gastrointestinal disorders are doing by looking at their symptoms and tissue samples over time.

  Recruiting at 16 sites Children's Hospital Medical Center, Cincinnati · Phoenix, Arizona and 18 other locations · NCT02523118

• National registry for pulmonary alveolar proteinosis

  This study is creating a national registry for people with pulmonary alveolar proteinosis to help improve diagnosis, treatment, and understanding of this rare lung disease.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT02461615

• Using hyperpolarized xenon MRI to assess lung function in adults

  This study is testing if a special type of MRI using xenon gas can help us see how well the lungs are working in healthy adults.

  Recruiting Phase 1/2 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT02316379

• Using hyperpolarized xenon gas for lung imaging in children and adults

  This study is testing if breathing in a special gas during MRI scans can help doctors see how well the lungs are working in both healthy people and those with breathing problems.

  Recruiting Phase 1/2 Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT02272049

• Transplant for Patients with Fanconi Anemia Using Adjusted Chemotherapy

  This study is testing a new way to use lower doses of chemotherapy before a stem cell transplant to see if it can safely help people with Fanconi anemia and serious blood disorders.

  Recruiting at 2 sites Phase 2 Children's Hospital Medical Center, Cincinnati · New York, New York and 2 other locations · NCT02143830

• Using donor-derived T-cells to treat viral infections after stem cell transplants

  This study is testing whether T-cells from stem cell donors can help patients who have infections after their transplants fight off those viruses.

  Recruiting at 2 sites Phase 1/2 Children's Hospital Medical Center, Cincinnati · Akron, Ohio and 2 other locations · NCT02048332

• Understanding eosinophilic disorders and their mechanisms

  This study is trying to understand how certain immune cells behave in people with eosinophilic disorders, like food allergies and gastrointestinal issues, to see how these conditions affect their health.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT00267501

Quick answers

How many clinical trials run by Children's Hospital Medical Center, Cincinnati are recruiting right now?

113, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United States (108 trials), Uganda (4 trials), Tanzania (2 trials), Ghana (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 14, Phase 1/2: 7, Phase 4: 6, Phase 1: 5. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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