Tailored program to help teens and young adults with cancer take their meds
Official title: A Tailored Medication Adherence-Promotion Intervention for Adolescents and Young Adults With Cancer
Run by Children's Hospital Medical Center, Cincinnati · NCT07223463 · Data updated 2026-11-12
A tailored program is being tested to see if it helps adolescents and young adults with cancer take their oral medications more consistently than the standard approach.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 15 Years to 24 Years |
| Sex | All |
| Enrollment | 160 (estimated) |
| Sponsor | Children's Hospital Medical Center, Cincinnati Academic / other |
| Locations | 4 sites (Kansas City, Kansas and 3 other locations) |
| Status | Recruiting |
| Started | August 31, 2026 |
| Main results expected | January 31, 2030 |
| Study ends | August 31, 2030 |
| Registry record updated | September 24, 2026 |
| Trial ID | NCT07223463 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are 15 to 24.99 years old with cancer who are prescribed an oral anticancer agent and are fluent in English with no major cognitive barriers.
✕Probably not a fit
Patients who are highly adherent at run-in, face language barriers, or have conditions precluding participation may not benefit from the tailored approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized trial compares a Tailored Program to a uniform standard-of-care Feedback Program in AYAs with cancer. Participants use an electronic pill bottle to monitor adherence, complete questionnaires at multiple timepoints, and participate in program sessions. The study aims to see if the tailored approach improves medication adherence, quality of life, and reduces healthcare use. Eligible participants are 15 to 24.99 years old with cancer and on an oral anticancer agent or prophylaxis.
Why it matters
Potential benefit: If successful, the tailored program could improve medication adherence and potentially enhance quality of life for AYAs with cancer.
How similar studies have gone: Previous adherence-promotion efforts in cancer exist, but this tailored comparison against uniform standard care is a novel approach in AYAs.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient is 15.00 to 24.99 years of age * Patient is diagnosed with cancer * Patient is prescribed an oral anticancer/antitumor agent or prophylaxis Exclusion Criteria: * Patient is not fluent in English * Patient evidences significant cognitive deficits * Patient's medical status or treatment precludes participation * Patient enrolled on a medical trial requiring medication storage in a trial-provided container * Patient demonstrates greater than or equal to 95% adherence during run-in period * Patient declines to use or has difficulty using electronic adherence monitoring device during run-in
Where it's running
-
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States Recruiting -
Seattle Children's Hospital
Seattle, Washington, United States Recruiting -
The University of Kansas Medical Center
Kansas City, Kansas, United States Not yet recruiting -
Columbia University Irving Medical Center
New York, New York, United States Not yet recruiting
Study contacts
- Principal investigator: Meghan E. McGrady, PhD — Children's Hospital Medical Center, Cincinnati
- Study coordinator: Meghan E. McGrady, PhD
- Email: Meghan.McGrady@cchmc.org
- Phone: 513-803-8044
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.