Mapping the prevalence of sickle cell disease in Uganda

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to determine the prevalence of sickle cell trait (SCT) and sickle cell disease (SCD) across all districts in Uganda. By analyzing approximately 90,000 dried blood spot samples collected from HIV-exposed infants over a 12-month period, the study will provide crucial data on the burden of SCT and SCD in the country. The researchers will utilize advanced techniques such as hemoglobin analysis and geospatial mapping to illustrate the prevalence of these conditions and their associations with malaria and HIV. The findings will help inform public health strategies and interventions for sickle cell disease in Uganda.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Up to 1,000,000 samples may be collected during 2015 - 2030 following primary analysis based on surveillance findings.

Exclusion Criteria:

* Repeat samples on the same individuals during the study period will be excluded.

Where it's running

• Makerere University
  Kampala, Uganda Recruiting
• Minister of Health
  Kampala, Uganda Recruiting
• National Coordinator EID Program
  Kampala, Uganda Recruiting
• Sickle Cell Clinic Department of Pediatrics & Child Health Mulago Hospital
  Kampala, Uganda Recruiting

Study contacts

• Principal investigator: Russell Ware, MD, PhD — Children's Hospital Medical Center, Cincinnati
• Study coordinator: Teresa Latham, MA
• Email: teresa.latham@cchmc.org
• Phone: 5138037922

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Newborn Sickle Cell Screening in Mozambique

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• Optimizing Hydroxyurea in Children with Sickle Cell in Africa

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• Hematopoietic stem cell editing to treat sickle cell disease

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• Virtual reality options to help with VOC pain in adults with SCD

  This study tests whether headset-based virtual reality can help reduce pain for adults with sickle cell disease during vaso-occlusive crises treated in an infusion center.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT07674277

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.