Measuring brain network activity to predict and improve outcomes in children with dystonia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The study uses EEG and EMG recordings at rest and during a simple motor reaction task to map cortical and subcortical motor network activity in children with dystonia. Children who have deep brain stimulation will be tested with the device both on and off to measure effects of chronic and active stimulation on network function. Data from dystonia participants will be compared to typically developing controls to track how motor networks evolve with development. Researchers aim to identify neural patterns that predict response to DBS and could guide individualized stimulation settings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* For dystonia subjects:
* Dx of dystonia (with and without DBS)
* willingness and ability to complete study protocols.
* For Typically Developing Controls:
* normal developmental milestones
* absence of any neuropsychiatric disorder
* no significant medical condition.

Exclusion Criteria:

* history of epilepsy
* presence of implanted medical devices (except DBS in dystonia subjects)
* lack of cognitive or physical ability to complete study protocol.

Where it's running

• Cincinnati Children's Hospital Medical Center
  Cincinnati, Ohio, United States Recruiting

Similar studies

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.