Understanding sound perception in preschoolers with Fragile X Syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates how children with Fragile X Syndrome (FXS) perceive sound and language compared to typically developing peers. Using a combination of behavioral assessments, neuroimaging techniques like EEG and fNIRS, and hearing tests, the research aims to identify early markers of speech and language impairments in preschool-aged children with FXS. By comparing responses to sounds in children with FXS to those of typically developing children and those with a history of premature birth, the study seeks to uncover the neural mechanisms underlying auditory hypersensitivity and its impact on language development.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnoses of Fragile X Syndrome, Typical Development, or History of Premature Birth
* able to sit independently
* English is spoken at home

Exclusion Criteria:

* For all participants: no seizures in the past 6 months
* For typical development group and Fragile X group: not born prior to 32 weeks gestation

Where it's running

• Cincinnati Children'S Hospital
  Cincinnati, Ohio, United States Recruiting

Study contacts

• Study coordinator: Elizabeth Smith, PhD
• Email: elizabeth.smith3@cchmc.org
• Phone: 5135171383

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Using sound to improve cognitive function and sensory sensitivity in youth with developmental disorders

  This study is testing if listening to special sounds can help improve thinking skills and reduce sensitivity to noise in children with Fragile X Syndrome and Autism Spectrum Disorder.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.