Effects of soy milk on liver health in children with fatty liver disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the impact of daily soy milk consumption compared to 2% fat cow's milk on the severity of Non-alcoholic Fatty Liver Disease (NAFLD) in children. It is a randomized, controlled trial that aims to determine if soy isoflavones can help reduce NAFLD and related obesity issues. The study will monitor liver health through MRI assessments and evaluate potential benefits without expecting adverse effects from soy consumption.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Children with overweight/obesity
* Known NAFLD or elevated ALT (\>30)

Exclusion Criteria:

* Baseline habitual (\>3 days per week) consumption of soy foods
* Allergy to soy or cow's milk protein
* Inability to undergo MRI
* Recent (past 8 weeks) antibiotic exposure
* Treatment for existing endocrine disorders
* MRI PDFF \<10%

Where it's running

• Cincinnati Children's Hospital Medical Center
  Cincinnati, Ohio, United States Recruiting

Study contacts

• Study coordinator: Ann Popelar
• Email: Ann.Popelar@cchmc.org
• Phone: (513) 636-8867

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.