Clinical trial Recruiting at 1 site Observational Ages 5 and up

Proton MRI of Musculoskeletal and Lung Health

Official title: Ultra-Short Echo Time 1H MRI in Individuals With Thoracic Musculoskeletal Disorders

Run by Children's Hospital Medical Center, Cincinnati · NCT07845708 · Data updated 2026-11-12

This study tests MRI techniques to take clearer pictures of the lungs in healthy people and those with lung, muscle, or bone conditions.

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Quick facts

Study typeObservational
Ages5 Years and up
SexAll
Enrollment100 (estimated)
SponsorChildren's Hospital Medical Center, Cincinnati
Academic / other
Locations1 site (Cincinnati, Ohio)
StatusRecruiting
StartedJune 17, 2025
Main results expectedJune 2030
Study endsJune 2030
Registry record updatedOctober 16, 2026
Trial IDNCT07845708 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals 5 years and older, including healthy volunteers and those with lung, muscle, or bone conditions willing to undergo MRI scans.

Probably not a fit

Participants whose conditions do not affect lung imaging or who cannot undergo MRI may see no direct benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will use advanced MRI methods, including UTE and bSSFP, along with standard MRI, to image the lungs. The study collects MRI images and health information from participants aged 5 and older, spanning healthy individuals and those with various lung, musculoskeletal, or bone diseases. The goal is to better understand how lung structure varies across health and disease and to improve future imaging approaches. This is an observational study at Cincinnati Children's Hospital Medical Center led by Laura Walkup.

Why it matters

Potential benefit: If successful, the study could improve our understanding of lung imaging and help guide future MRI techniques for better diagnosis and monitoring.

How similar studies have gone: Past research has shown promise with advanced lung MRI techniques, supporting the feasibility of this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 5 years

Exclusion Criteria:

* History of any comorbidity reviewed at the Screening phone call that, in the opinion of the investigator, might confound the results of the study or pose an additional risk to the subject.
* Standard MRI exclusion criteria as set forth by the CCHMC Radiology Department and IRC.
* Pregnancy

Where it's running

  • Cincinnati Children's Hospital Medical Center
    Cincinnati, Ohio, United States
    Recruiting

Study contacts

  • Principal investigator: Laura Walkup, PhD — Children's Hospital Medical Center, Cincinnati
  • Study coordinator: Ashley Borden, MPH
  • Email: ashley.borden@cchmc.org
  • Phone: 5136360143

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.