Improving care for infants with complex heart conditions

National Pediatric Cardiology Quality Improvement Collaborative (NPC-QIC) - A Collaborative Initiative to Improve Care of Children With Complex Congenital Heart Disease

Observational Children's Hospital Medical Center, Cincinnati · NCT02852031

This study is trying to improve the care and outcomes for infants with Hypoplastic Left Heart Syndrome by collecting important health information and involving parents in their treatment.

Quick facts

Study typeObservational
Enrollment1000 (estimated)
AgesN/A to 15 Months
SexAll
SponsorChildren's Hospital Medical Center, Cincinnati Academic / other
Locations63 sites (Birmingham, Alabama and 62 other locations)
Trial IDNCT02852031 on ClinicalTrials.gov

What this trial studies

This initiative aims to enhance the care and outcomes for infants diagnosed with Hypoplastic Left Heart Syndrome (HLHS) by expanding a national registry to collect clinical and developmental data. It focuses on implementing consensus standards into daily practices across pediatric cardiology centers and actively involves parents in the care process. The study will gather information on infants from diagnosis until they reach 12 months of age, facilitating better understanding and management of HLHS.

Who should consider this trial

Good fit: Ideal candidates for this initiative are fetuses or newborns diagnosed with HLHS or other univentricular conditions who are intended to undergo the Norwood procedure.

Not a fit: Patients who do not have HLHS or are not undergoing the Norwood procedure may not benefit from this initiative.

Why it matters

Potential benefit: If successful, this initiative could lead to improved health outcomes and quality of life for infants with HLHS.

How similar studies have performed: Other studies focusing on collaborative care and registry-based approaches have shown promise in improving outcomes for similar patient populations.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Fetuses or newborns diagnosed with HLHS or other univentricular condition
* Intended to undergo Norwood procedure

Exclusion Criteria:

* None

Where this trial is running

Birmingham, Alabama and 62 other locations

+13 more sites — see ClinicalTrials.gov for the full list.

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hypoplastic Left Heart Syndrome
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.