FST Decision Support to Help Timely Therapy for Kids with AKI Risk

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will use risk markers like the Renal Angina Index and NGAL to identify high-risk PICU patients and then compare outcomes before and after introducing a decision-support tool to standardize the furosemide stress test. The project uses a hybrid effectiveness-implementation approach to see if clinicians find the tool acceptable and feasible and whether it reduces fluid overload and helps predict dialysis needs. The effort builds on prior work with AKI risk stratification and biomarkers to guide management in critically ill children. The goal is to determine if a standardized FST pathway improves timely decision-making around dialysis and overall outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Admitted to the pediatric intensive care unit (PICU)
* Renal Angina Index (RAI) greater than or equal to 8 (RAI+)
* Urine NGAL greater than or equal to 150 ng/mL (NGAL+)

Exclusion Criteria:

* Receipt of renal replacement therapy prior to PICU admission

Where it's running

• Cincinnati Children's Hospital Medical Center
  Cincinnati, Ohio, United States Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.