Heart Institute Biorepository for children with heart disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Heart Institute Biorepository is a prospective and retrospective observational collection that acquires, processes, organizes, and stores biological samples from patients seen at the Heart Institute. Samples include whole blood for DNA, plasma, urine, saliva, cardiovascular tissue, and explanted non-human prosthetics or grafts, and may be collected at surgery, catheterization, clinic visits, delivery, or other clinical encounters. The repository performs limited laboratory processing such as DNA isolation, plasma separation, and B-lymphocyte transformation to create immortalized cell lines and preserve genomic material for future use. Stored specimens are governed for investigator-initiated, translational, clinical, and outcomes research to serve institutional and broader research needs.

Why it matters

Who can join: the full rules

Inclusion Criteria

* Any fetus, child or adult at risk of or diagnosed with Pediatric Heart Disease (PHD) or Cardiovascular Disease (CVD)
* Any HI patient, including the following types of encounters: Surgery or Cardiac Catheterization or Advanced Imaging encounters, Inpatient, including Cardiology service, consultation patients and Fetal Delivery, and Outpatient, including all HI-associated clinics and consultation services
* Any female carrying a fetus with a suspected cardiac diagnosis

Exclusion Criteria

* Legal guardian unauthorized to consent
* Families who choose Palliative care during pregnancy

Where it's running

• Children's Hospital Medical Center, Cincinnati
  Cincinnati, Ohio, United States Recruiting

Study contacts

• Principal investigator: Jeffrey Alten — Children's Hospital Medical Center, Cincinnati
• Study coordinator: Jeffrey Alten, MD
• Email: HIBioRepository@cchmc.org
• Phone: 513-636-2871

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.