Condition

Venous Thromboembolism clinical trials and research

• 50Clinical trials
• 23NIH research projects
• 41Countries

Newest Venous Thromboembolism clinical trials

All recruiting trials (50)

• DoACs vs LMWH for blood flow after knee replacement

  This study tests whether rivaroxaban, apixaban, or LMWH work differently to support blood flow in the legs after total knee replacement in adults.

  Recruiting Military Hospital of Tunis · Tunis, Tunis Governorate · NCT07869615

• Prognostic value of the 2026 AHA/ACC PE classification in ED patients with acute PE

  This study tests whether the 2026 AHA/ACC five-category PE classification helps predict 30-day major adverse pulmonary embolism events in adults with acute PE presenting to the ED.

  Recruiting Marmara University Pendik Training and Research Hospital · Istanbul · NCT07805616

• Screening for blood clots in adults with acute heart failure

  This trial tests whether a guideline-based screening approach can detect pulmonary embolism in adults admitted with acute heart failure.

  Recruiting University Hospital, Angers · Agen and 9 other locations · NCT07499661

• Blood test and software to guide treatment for venous thromboembolism

  This project tests whether a blood-based ctDNA test combined with a software risk score can predict if VTE will come back in adults with cancer-associated DVT or PE who have finished 3–12 months of anticoagulation.

  Recruiting at 7 sites Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 7 other locations · NCT07399977

• Aspiration thrombectomy with the Symphony or Prodigy devices

  This project will try the Symphony and Prodigy aspiration thrombectomy devices to remove arterial, venous, or pulmonary blood clots in adults.

  Recruiting at 13 sites Imperative Care, Inc. · Huntsville, Alabama and 12 other locations · NCT07350499

• Combining European cohort data to find biomarkers that guide treatment for venous thromboembolism

  This project combines clinical, biological and imaging data from European patient cohorts to try to find biomarkers that predict clot recurrence, bleeding, or death in people with venous thromboembolism.

  Recruiting University Hospital, Brest · Brest · NCT07328152

• Rosuvastatin to help prevent blood clots in cancer patients

  This study tests whether taking rosuvastatin daily for a year can lower the chance of dangerous blood clots in people with newly diagnosed or relapsed cancer who aren’t planned to receive blood-thinning medicine.

  Recruiting at 7 sites Phase 4 Brigham and Women's Hospital · Irvine, California and 8 other locations · NCT07303816

• Predicting Blood Clots in Cancer Patients on Chemotherapy

  This study tests whether blood biomarkers measured during chemotherapy can predict which cancer patients will develop a venous thromboembolism (VTE).

  Recruiting at 3 sites University of Dublin, Trinity College · Cork, Ireland and 2 other locations · NCT07196020

• Apixaban versus enoxaparin to prevent blood clots after head and neck cancer surgery

  This compares apixaban pills to daily enoxaparin shots to see if the pill is a safe and easier way to prevent blood clots after head and neck cancer surgery.

  Recruiting Phase 4 State University of New York - Upstate Medical University · Syracuse, New York · NCT07189897

• Comparing SRSD107 and enoxaparin to prevent clots after total knee replacement

  It will test whether three dose levels of an experimental drug, SRSD107, work as well and are as safe as daily enoxaparin for preventing blood clots in adults aged 60–80 having elective primary unilateral total knee replacement.

  Recruiting Phase 2 Sirius Therapeutics Co., Ltd. · Nové Město na Moravě · NCT07140523

• Comparing Pulsed Electromagnetic Field Therapy and Pneumatic Compression for Preventing Blood Clots in ICU Patients

  This study is testing whether Pulsed Electromagnetic Field Therapy works better than pneumatic compression to prevent blood clots in ICU patients who can't take medication for it.

  Recruiting Phase 4 Science Valley Research Institute · Belo Horizonte, BH · NCT06958588

• Predicting thrombosis risk in lung cancer patients on immune therapy

  This study is trying to see if certain factors can help predict the risk of blood clots in lung cancer patients receiving immune therapy.

  Recruiting at 5 sites Beijing Chao Yang Hospital · Zhengzhou, Henan and 4 other locations · NCT06950697

• Kinisoquin to prevent blood clots in people with advanced pancreatic cancer

  This trial will test whether Kinisoquin can prevent blood clots in people starting chemotherapy for metastatic or locally advanced pancreatic cancer.

  Recruiting at 3 sites Phase 3 Quercis Pharma AG · Ventura, California and 2 other locations · NCT06861088

• Timing of anticoagulation for preventing blood clots in patients with brain hemorrhage

  This study is testing whether starting blood-thinning treatment early or later can help prevent blood clots in patients with bleeding in the brain while keeping them safe from more bleeding.

  Recruiting Pirogov Russian National Research Medical University · Moscow · NCT06753786

• Improving decision-making for managing unprovoked venous thromboembolism

  This study is testing a new way to help patients with unprovoked blood clots decide how long to take blood thinners, to see if it leads to better health outcomes.

  Recruiting University Hospital, Brest · Brest, France and 19 other locations · NCT06731244

• Evaluating complications of anticoagulant treatment in cancer patients with blood clots

  This study looks at how often blood clots and bleeding problems happen in cancer patients who are being treated with blood thinners.

  Recruiting at 2 sites IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna and 1 other locations · NCT06714734

• Managing blood clot prevention in cancer patients with catheter-related DVT

  This study is testing whether giving a low dose of a blood thinner to cancer patients with a history of blood clots can help prevent new clots from forming.

  Recruiting at 2 sites Phase 4 Ottawa Hospital Research Institute · Ottawa, Ontario and 1 other locations · NCT06603870

• Personalized blood thinner treatment for hip and knee replacement patients

  This study is testing if personalized blood thinner treatments can better prevent blood clots and bleeding in patients getting hip or knee replacements compared to standard treatments.

  Recruiting at 12 sites Phase 4 Leiden University Medical Center · Apeldoorn, Gelderland and 12 other locations · NCT06581965

• Comparing apixaban to no anticoagulant in surgery patients

  This study is testing if taking the blood thinner apixaban for 28 days after abdominal or pelvic surgery can help prevent blood clots in patients who are at risk.

  Recruiting Phase 4 Clinical Urology and Epidemiology Working Group · Helsinki · NCT06523959

• Postpartum aspirin to prevent blood clots after delivery

  A 3rd-phase trial tests whether taking a small daily dose of aspirin for 6 weeks after giving birth works as well as usual preventive injections of LMWH to reduce blood clots in people with pregnancy-related clotting risk.

  Recruiting Phase 3 University of Calgary · Brussels and 11 other locations · NCT06494878

• Evaluating a new decision support tool for diagnosing blood clots

  This study is testing a new tool to help doctors diagnose blood clots in patients who might have conditions like pulmonary embolism or deep vein thrombosis, using fresh blood samples.

  Recruiting at 4 sites Diagnostica Stago R&D · Niort, Sartres and 3 other locations · NCT06480994

• Colchicine to reduce inflammation after proximal deep vein thrombosis

  This trial will try daily low‑dose colchicine (0.5 mg) versus a matching placebo in adults with a first proximal lower‑leg DVT to see if it lowers the chance of developing post‑thrombotic syndrome.

  Recruiting at 3 sites Phase 3 Ottawa Hospital Research Institute · Ottawa, Ontario and 3 other locations · NCT06440694

• Effects of a Walking Test on Blood Clotting in Patients

  This study tests how a 60-minute walking test affects blood clotting in people with and without a history of blood clots.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes, Occitanie · NCT06418633

• Lowering stomach and intestinal bleeding with omeprazole in older adults with a new blood clot

  This pilot will test whether taking omeprazole reduces stomach or intestinal bleeding in people 65 and older who are starting blood thinners for a new venous blood clot.

  Recruiting at 6 sites Phase 3 Ottawa Hospital Research Institute · Ottawa, Ontario and 6 other locations · NCT06393868

• Smart technology for patient-centered care in pulmonary embolism

  A smartphone-based program using wearable tech and AI will help people with pulmonary embolism manage their health and see if it improves long-term outcomes.

  Recruiting Navy General Hospital, Beijing · Beijing, Beijing Municipality · NCT06382038

• Using advanced imaging to predict the risk of blood clot recurrence in pulmonary embolism patients

  This study is testing if advanced imaging can help find out which patients with a history of pulmonary embolism are at risk for blood clots coming back, so they can get the right treatment.

  Recruiting at 11 sites University Hospital, Brest · Amiens, France and 12 other locations · NCT06372730

• Comparing rivaroxaban and low-molecular weight heparin for preventing blood clots in patients with lower limb trauma

  This study is testing if a new blood thinner called rivaroxaban can prevent blood clots better than a standard treatment in patients with leg injuries who are at high risk for clots.

  Recruiting at 26 sites Phase 3 University Hospital, Angers · Agen and 36 other locations · NCT06195540

• Evaluating the use of compression stockings for patients needing blood-thinning medication after surgery

  This study is testing if wearing compression stockings can help high-risk surgical patients who are on blood-thinning medication avoid dangerous blood clots.

  Recruiting at 3 sites Imperial College London · Bristol and 2 other locations · NCT06166537

• Preventing blood clots in cancer patients receiving treatment

  This study is testing if the blood thinner rivaroxaban can help prevent blood clots in cancer patients with genitourinary cancers who are starting treatment.

  Recruiting Phase 2/3 Ottawa Hospital Research Institute · Ottawa, Ontario · NCT05920343

• Using supplemental oxygen to treat pulmonary embolism

  This study is testing if giving extra oxygen to people with acute pulmonary embolism can help their heart function better and improve their overall health.

  Recruiting Early Phase 1 Massachusetts General Hospital · Boston, Massachusetts · NCT05891886

• Study on the safety and performance of Celect Platinum Vena Cava Filters

  This study is testing how safe and effective the Celect Platinum Vena Cava Filters are for patients over time after they've had them placed in their bodies.

  Recruiting at 7 sites Cook Group Incorporated · Los Angeles, California and 6 other locations · NCT05881798

• Evaluating anticoagulation management during pregnancy and postpartum

  This study is trying to see how well anticoagulation management works for pregnant people using a specific medication to help prevent blood clots during and after pregnancy.

  Recruiting at 14 sites University of Calgary · Durham, North Carolina and 13 other locations · NCT05756244

• Preventing blood clots in patients undergoing varicose vein treatment

  This study tests different blood-thinning medications to see which one best helps prevent blood clots in adults getting treatment for varicose veins.

  Recruiting Phase 4 Imperial College London · London · NCT05735639

• Comparison of ClotTriever System and Anticoagulation for Deep Vein Thrombosis

  This study is testing if the ClotTriever System can help people with painful deep vein blood clots feel better compared to the usual blood-thinning medications.

  Recruiting at 48 sites Inari Medical · Scottsdale, Arizona and 63 other locations · NCT05701917

• Preventing blood clots in outpatients with newly diagnosed grade 4 glioma using apixaban

  This trial will test whether taking apixaban can prevent dangerous blood clots in adults newly diagnosed with grade 4 glioma.

  Recruiting Phase 2 University of Vermont Medical Center · Burlington, Vermont · NCT05683808

• Using geko device to prevent blood clots in stroke patients

  This study is testing if the geko™ device can help prevent blood clots in stroke patients who can’t move around, compared to the standard treatment they usually get.

  Recruiting at 17 sites Firstkind Ltd · Bury St Edmunds, Suffolk and 17 other locations · NCT05476913

• Registry for the use of NOACs in patients with Atrial Fibrillation or Venous Thromboembolism

  This study is looking to see how well new blood thinners called NOACs work for people with Atrial Fibrillation or blood clots, by tracking their treatment and outcomes over time.

  Recruiting Henan Provincial People's Hospital · Zhengzhou, Henan · NCT05378308

• Evaluating DOAC levels in Chinese patients with atrial fibrillation

  This study is testing how stopping blood-thinning medication for a short time affects Chinese patients with atrial fibrillation to see if it's safe for them during medical procedures.

  Recruiting Chinese University of Hong Kong · Hong Kong · NCT05378035

• Preventing blood clots in cancer patients with central venous catheters

  This study is testing if a daily dose of a blood thinner called rivaroxaban can help prevent blood clots in cancer patients who have just had a central venous catheter placed.

  Recruiting at 11 sites Phase 3 Ottawa Hospital Research Institute · Halifax, Nova Scotia and 10 other locations · NCT05029063

• Using rosuvastatin to reduce blood clots in patients with venous thromboembolism

  This study is testing if adding rosuvastatin, a cholesterol-lowering drug, can help prevent blood clots from coming back in patients who have recently had a major blood clot event.

  Recruiting at 19 sites Phase 3 Ottawa Hospital Research Institute · Calgary, Alberta and 30 other locations · NCT04319627

• Comparing daily doses of aspirin to prevent blood clots after joint surgery

  This study tests if taking a low dose of aspirin once a day is just as good as taking it twice a day to prevent blood clots in people having hip or knee surgery.

  Recruiting Phase 2 University of Miami · Miami, Florida · NCT04295486

• Comparing clinical surveillance to anticoagulation for low-risk patients with isolated pulmonary embolism

  This study is testing whether low-risk patients with isolated pulmonary embolism can safely be monitored without blood thinners instead of taking them.

  Recruiting at 29 sites Phase 4 Insel Gruppe AG, University Hospital Bern · Woluwe-Saint-Lambert, Brussels Capital and 39 other locations · NCT04263038

• Using Sulodexide to prevent blood clots in elderly patients

  This study is testing if a medication called Sulodexide can help prevent blood clots in elderly patients who have already had one, while being safer than current treatments.

  Recruiting Phase 3 Arianna Anticoagulazione Foundation · Rozzano · NCT04257487

• CHIPs-VTE program to prevent hospital-acquired blood clots in hospitalized patients

  This project tests whether a hospital-wide package of risk checks, computer alerts, staff education, and audits can increase appropriate clot-prevention for hospitalized patients in China.

  Recruiting China-Japan Friendship Hospital · Beijing, Beijing Municipality · NCT04211181

• Identifying biomarkers for detecting hidden cancer in patients with blood clots

  This study is trying to find new markers in the blood that can help spot hidden cancer in patients who have blood clots.

  Recruiting at 2 sites Danderyd Hospital · Stockholm and 1 other locations · NCT03781531

• Computerized alerts to prevent blood clots in hospitalized patients

  This study is testing if using computer alerts can help doctors give blood clot prevention medication to hospitalized patients who are at risk.

  Recruiting Brigham and Women's Hospital · Boston, Massachusetts · NCT03728166

• Validation of Caprini Score for Patients Undergoing Varicose Vein Surgery

  This study is testing if the Caprini score can help identify adults having varicose vein surgery who are at higher risk for blood clots after their procedure.

  Recruiting Pirogov Russian National Research Medical University · Moscow · NCT03041805

• Registry for patients with venous blood clots

  This study is creating a database of patients with blood clots to help doctors better understand how to treat them and identify those at higher risk for complications.

  Recruiting at 184 sites Foundation for the study of VTE diseases. (FUENTE) · New Haven, Connecticut and 304 other locations · NCT02832245

• Survey on patients using anticoagulant medications

  This study is looking at how well different blood-thinning medications work and their safety for adults who are starting or changing their anticoagulant treatment.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna, BO · NCT02219984

• Registry for patients undergoing IVC filter placement or retrieval

  This study is collecting information from patients getting an IVC filter placed or removed to see how different removal methods work over time.

  Recruiting Stanford University · Stanford, California · NCT01158482

NIH-funded research (23)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Statins to Prevent Cancer-Associated Blood Clots in Cancer Patients

  A large study will test whether taking rosuvastatin every day for a year can lower the chance of dangerous blood clots in people with cancer, without raising the risk of bleeding.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11606487

• Optimal use of blood thinners for venous clots in people with cirrhosis

  This grant hopes to figure out the safest and most effective way to use oral anticoagulants for adults with cirrhosis who develop venous clots.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11427117

• PET/CT imaging to detect chemotherapy-related vascular harm in young cancer patients

  A non-invasive PET/CT scan method using standard care imaging is being tested to identify which pediatric and young adult cancer patients are at higher risk of blood clots from chemotherapy.

  NIH research Research Inst Nationwide Children's Hosp · Columbus, United States · NIH-11396394

• Statins to Prevent Cancer-Associated Blood Clots in Cancer Patients

  A large clinical trial will test whether taking rosuvastatin daily for a year helps prevent dangerous blood clots in people with newly diagnosed or relapsed cancer who aren’t already getting anticoagulants.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11387857

• BCOR's role in blood clot risk and liver genetics

  A Johns Hopkins-led study is exploring how a human gene, BCOR, may control liver-produced clotting factors to influence venous blood clots.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11378452

• Personalized risk-prediction for hospital-acquired blood clots in adults

  A real-time risk model helps doctors identify adults in the hospital who are at higher risk of developing blood clots so they can prevent them safely.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11373022

• Genomic and Proteomic Markers for Recurrent Venous Thromboembolism

  Researchers are studying genetic and protein clues to predict who will have another blood clot after an initial VTE event, so doctors can tailor safer, more effective care.

  NIH research University of Washington · Seattle, United States · NIH-11364727

• Venous clot complications after a first VTE in adults

  This study follows adults after a first venous thromboembolism to understand chronic symptoms and health outcomes over the first year.

  NIH research Kaiser Foundation Research Institute · Oakland, UNITED STATES · NIH-11332768

• STOP-SCD-VTE: How and when blood thinners are used for adults with sickle cell disease and blood clots

  A real-world study of how doctors use long-term blood thinners in adults with sickle cell disease who have had a venous clot, and whether different medicines or patterns affect outcomes.

  NIH research Boston University Medical Campus · Boston, United States · NIH-11297560

• How the BCOR gene may affect risk of dangerous blood clots

  Researchers are looking at how the BCOR gene controls a liver protein called Factor VII that can influence the risk of venous blood clots for people prone to VTE.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11146625

• Better ways to predict and prevent blood clots in the hospital

  This work creates and tests a new way to help doctors quickly identify hospitalized patients at risk for dangerous blood clots, aiming to prevent them before they happen.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11142579

• Using PET/CT scans to spot vein inflammation and clot risk in children and young adults with cancer

  This project uses PET/CT scans with a glucose tracer to look for vein inflammation that may signal higher risk of dangerous blood clots in children, adolescents, and young adults receiving chemotherapy.

  NIH research Research Inst Nationwide Children's Hosp · Columbus, United States · NIH-11132970

• Understanding long-term effects of blood clots

  This study is looking at how people who have had a blood clot, like deep vein thrombosis or pulmonary embolism, might feel in the year after their treatment, especially those using newer blood thinners, to better understand their symptoms and help improve their recovery and care.

  NIH research Kaiser Foundation Research Institute · Oakland, UNITED STATES · NIH-11098542

• Preventing blood clots in cancer patients receiving outpatient care

  This study is looking at ways to help doctors better prevent blood clots in cancer patients who are not in the hospital, so they can stay safer and healthier during their treatment.

  NIH research University of Vermont & St Agric College · Burlington, United States · NIH-11094449

• Understanding risks and outcomes of blood clots in young patients

  This study is looking at blood clots in young people under 21 to find better ways to predict how they will do and improve their treatment, all while helping new researchers learn more about this important health issue.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11036368

• Investigating delays in diagnosing venous thromboembolism in different healthcare settings

  This study is looking into why some people with blood clots, like pulmonary embolism and deep vein thrombosis, don’t get diagnosed quickly, and it aims to find ways to improve care for everyone, whether they live in cities or rural areas.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11020773

• Understanding how BCOR affects blood clotting and venous thromboembolism

  This study is looking at how certain genes, especially one called BCOR, might affect the chances of developing blood clots, which can be a serious health issue, and it hopes to find new ways to help prevent or treat this condition.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-10942118

• Understanding blood clot risks in children with sickle cell disease

  This study is looking at what might cause blood clots in children with sickle cell disease, so we can find better ways to prevent and treat these clots and help keep kids healthier.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-10907804

• Investigating anticoagulant use for preventing blood clots in patients with inflammatory bowel disease

  This study is looking at how well blood-thinning medications can help prevent blood clots in people with inflammatory bowel disease, both when they're in the hospital and at home, while also making sure these treatments are safe for those who might be at higher risk.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-10893637

• Improving decision support systems for preventing blood clots in hospitalized patients

  This study is working on improving tools that help doctors make better decisions about preventing blood clots, so patients can get the best care based on the latest research.

  NIH research University of Minnesota · Minneapolis, United States · NIH-10893358

• Improving prevention of blood clots in hospitalized patients

  This study is looking at ways to help hospitalized patients remember to take their blood clot prevention medications by using real-time support, so they can stay involved in their care and lower their chances of getting preventable blood clots.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-10794235

• A telemedicine solution using smart socks to prevent blood clots in older cancer patients

  This study is testing a fun and interactive sock that helps older cancer patients stay active and prevent blood clots by turning their foot and ankle exercises into a game, making it easier for them to keep moving and stay healthy.

  NIH research Stexole LLC · Houston, UNITED STATES · NIH-10547300

• Investigating the role of platelets in blood clot risks for cancer patients

  This study is looking at how certain blood cells called platelets might affect the risk of blood clots in cancer patients, and it hopes to find a way to identify those who are more likely to develop these clots so that better prevention methods can be created.

  NIH research University of Vermont & St Agric College · Burlington, United States · NIH-10531623

Related topics

Quick answers

How many Venous Thromboembolism clinical trials are recruiting right now?

50, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 41 countries. The most sites are in United States (14 trials), France (12 trials), Canada (9 trials), United Kingdom (7 trials), China (5 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 8, Phase 4: 8, Phase 2: 3, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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